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Zoom Meet-up for Those With MBC: Place to keep chatting
This is a space held for our Zoom Meetup members to gather in between meetings for updates and support. Join our Virtual Meet-ups! For those with a diagnosis of metastatic breast cancer (MBC; also called stage IV) Register: Mondays at 2:00 PM EST, Tuesdays at 1:00 PM EST, and Wednesdays at 4:00 PM EST Young (45 and under)…
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Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer
Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer Dec 22, 2025 Delaying cancer growth may keep people out of the chemo chair. Read more…
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Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease
Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease Jan 6, 2026 When treating breast cancer that’s spread to the cerebrospinal fluid, proton therapy controlled the cancer better than traditional X-ray radiation. Read more…
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Multiple skeletal Mets Strongly ER positive BC originally now showing as TNBC
originally diagnosed IDC grade 2 , stage 3A HR+ with Allred score 8/8 and HER2- at the age of 46, 10 years back . Surgery, chemo and radiation therapy done as part of treatment followed by 5 years of tamoxifen followed by 5 years of letrozole and Zolenic acid. Now got bone pain few months back. When done pet scan and MRI…
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Now Enrolling: Cognitive Outcomes & Partner Engagement in Metastatic Breast Cancer Study
Enrollment for Cognitive Outcomes & Partner Engagement in Metastatic Breast Cancer Study at the University of Texas at Austin has started. Through this remote study, we hope to understand how individuals living with metastatic breast cancer, along with their partners, deal with cognitive symptoms during their everyday…
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De Novo Stage IV
I'm wondering if there is a topic just for de novo Stage IV. I'd like to know how people found out. Did you have symptoms that led you to the doctor for an answer? Was it found out of the blue when you had another issue and how was it found? Are there others like me who have never shown it in your breast but only where it…
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Podcast: The Guy With Stage 4 Breast Cancer
The Guy With Stage 4 Breast Cancer December 2, 2025 Male breast cancer makes up about 1% of all breast cancer cases. The numbers are small, but it does happen. Jake Messier is living with metastatic breast cancer after first being diagnosed with stage II disease in 2023. Jake has very active Tik Tok and Instagram accounts…
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Clinical Trial Opportunity: Metastatic TNBC with EGFR expression and have lost HLA-A*02 expression
A2 Biotherapeutics is looking to recruit people with metastatic TNBC to a study on a CAR T therapy. The mTNBC must have EGFR expression and have lost HLA-A*02 expression. If you meet this criteria and would like to participate in this trial, you can email the study contact at: ClinicalTrials@a2bio .com Or, directly email…
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Fenbendazole, Ivermectin, Mebendazole, Methylene blue for Breast Cancer
I’m curious if anyone here has tried any of these. I’ve read some success stories but would love to hear firsthand experiences. It seems like the medical community has been hesitant to share much information about how these options might benefit people with cancer, whether it’s breast, colon, or other types.…
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MBC Patient-Centered Dosing Initiative | Take a Survey
The Right Dose for Every Patient The Patient-Centered Dosing Initiative (PCDI) is gathering insights from people living with metastatic breast cancer to advocate for dosing strategies that balance effectiveness and quality of life. If you are living with MBC in the U.S., take the PCDI survey by…
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Studies that prove early detection of stage IV recurrence extending survival time?
Can you please point me to any studies that show that early detection of metastatic stage IV breast cancer results in longer survival ? If this matters, I'm talking about ER+. HER2-. I know that it's a common opinion that early detection of such recurrence does not result in longer life, but are there any studies that…
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2017 BC Diagnosis…how are you doing?
Hello Friends:💐 It’s been awhile since I’ve checked in. I’m curious how my 2017 friends are doing. Have you had a recurrence? Is all going well? I’d love to know how everyone from 2017 is doing. I’m doing well. This site has been a huge support to me and I just want to thank you all again for your support. I look forward…
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Any studies that prove early detection of stage IV recurrence extending survival time?
Dear All, Can you please point me to any studies that show that early detection of metastatic stage IV breast cancer results in longer survival ? If this matters, I'm talking about ER+. HER2-. I know that the standard of care dictates that early detection of such recurrence does not result in longer life, but are there any…
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Help progressed to Brain Mets and fighting for the right treatment
Hi All, Been lurking on the stage 4 forum for some time. Now I need help. I live in the UK and attend UCLH where treatment seems to adopt a more cautious approach. Originally on Breast 09 trial but randomised and receive standard of care😢 6 rounds Doxetaxel and H & P. Over 2 years later and progression to Brain Mets. Upper…
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Important Stage IV Topics and Links for Stage IV Newbies
Here are some helpful resources if you've just been diagnosed with stage IV breast cancer, also known as metastatic or MBC. Join our free Virtual Support Groups for MBC! All with Metastatic Breast Cancer (MBC; also called stage IV) Register: Mondays at 2:00 PM EST, Tuesdays at 8:30 PM EST and Wednesdays at 4:00 PM EST…
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Likely to be diagnosed with bone mets and need some advice in the interim
Nearly 14 years after my initial diagnosis, I'm back at the rodeo. My tumor markers are up, and some pain in my leg that I thought was due to gait issues or sciatica is likely bone pain. I saw my MO today, and she said that the description of the pain is consistent with bone mets. Tomorrow, I will get called about when my…
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I was just now dx with skin mets
Hi, I've not had good news since forever—since suspected recurrence in August 2023 anyway, looks like I won't be getting any either. I had some red raised places — not bumps, not nodules, that would get red, then go away, etc. that appeared Nov. 23, the same month I was dx with St. IV. PET scan didn't show this. CTs-four…
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Just diagnosed with ILC mets
Hi, all I had ILC back in 2008. Had radical mastectomy on the right breast and prophylactic on the left. Chemo AC→T, radiation and 7 years of Arimidex. 16 years later I am back in the game. Still in discovery phase. Had FDG Pet Scan that shows liver uptake, had endoscopy that shows little spot in the stomach consistent…
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Dealing with Lymphedema w/o surgery?
Hi community. I'm posting since I haven't found a similar case yet. I opted out on surgery and chemo (too late), and it's been a good run for 7 years. The LE came on slowly to rt arm, dr diagnosed. Now its in both feet, then the left breast just swelled in size. No real noticeable discoloration. Has anyone else had LE…
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Wife is starting Xeloda soon
Hi all, My wife was diagnosed with mBC in 2023. She has been through 4-ish lines of treatment, the latest Enhertu. She has felt great with no side effects but it has stopped working after a year. This is next and I’m terrified of the side effects and what living with them will be like for us and our relationship. Can…