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  • MBJ
    MBJ Member Posts: 3,671
    edited June 2011

    Cyborg:  Before my BC diagnosis, I was told I had adrenal exhaustion--what is sometimes also called chronic fatigue.  I had completely wiped myself out gining 150% 24/7.  I am still trying to rebuild my immune system and adrenal damages from my former job. 

  • mollyann
    mollyann Member Posts: 148
    edited June 2011

    Luan,

    There are a couple of bioidentical threads under the alt, complementary and holistic area. You're right, there hasn't been much discussion of it in the last two months. But a number of the ER+/PR+ gals here do bioidentical hormones.

  • Luna5
    Luna5 Member Posts: 532
    edited June 2011

    Does anyone know of a reason NOT to use facial creams that are mostly DMAE ???

    I have one with DMAE Bitartrate, Veg Glycerin, Polysorbate 20, Sodium Chloride, Simethicone, Hydroxyethylcellulose, Potassium Sorbate, Sodium Benzoate, Citric Acid

    And another.... with DMAE, Stearic Acid, Thioctic (Alpha Lipoic) Acid, Allantoin, Panthenol, Caprylic /Capric Triglyceride, Organic Simmondsia Chinensis (Jojoba) Seed Oil, Cetyl Alcohol, Polysorbate, Glyceryl Stearate & Peg 100 Stearate, Tocopherol Acetate ( Vit E), ascorbyl Palmate (Ester-C),, Dimethicone, Retinyl Palmate (Vit A), Phenoxyethanol, Ethylhexyglycerin, Potassium Sorbate, Lavender Fragrance

    Thank you for advice on the safety of these products. 

  • mollyann
    mollyann Member Posts: 148
    edited June 2011

    Luna,

    You can enter your product into this database. http://www.ewg.org/skindeep/

    There used to be a database where you could enter each ingredient somewhere on the site.

    Good luck. I'm looking for a good DMAE cream myself. I bought the DMAE liquid and have been adding it to my regular skin cream.

  • luv_gardening
    luv_gardening Member Posts: 362
    edited June 2011

    Here's some info on progesterone.

    http://www.sciencedaily.com/releases/2010/05/100505133256.htm

    Cancer Researchers Link Ovarian Hormone to Breast Stem Cells Growth
    ScienceDaily (May 7, 2010)

     

  • Merilee
    Merilee Member Posts: 734
    edited June 2011

    Thanks for posting that Joy, information is always good to read.

  • lucy88
    lucy88 Member Posts: 100
    edited June 2011

    Thanks Joy. You might to want to add these to your research.

    Campagnoli C, Abba C, Ambroggio S, Peris C.
    Pregnancy, progesterone and progestins in relation to breast cancer risk.
    J Steroid Biochem Mol Biol 2005; 97(5):441-50.  
    The authors review recent findings that show that the production of progesterone
    during pregnancy and the use of bioidentical progesterone in hormone therapy do
    not increase breast cancer risk, and can even protect against the development of
    breast cancer.

    Kaaks R, et al.
    Serum sex steroids in premenopausal women and breast cancer risk within
    the European Prospective Investigation into Cancer and Nutrition (EPIC).  
    J Natl Cancer Inst 2005; 97:755-65.  
    In this large multicenter study, higher serum progesterone levels were associated
    with a significant reduction in breast cancer risk.

    Fournier A, Berrino F, Riboli E, Avenel V, Clavel-Chapelon F.  
    Breast cancer risk in relation to different types of hormone replacement
    therapy in the E3N-EPIC cohort.  Int J Cancer 2005; 114(3):448-54.  
    Combined HRT with estrogen (either oral or transdermal) and synthetic progestins
    was found to carry a significantly increased risk of breast cancer compared with
    estrogens plus oral micronized progesterone.  In fact, no increase in breast
    cancer risk was seen in the estrogen plus oral micronized progesterone group
    compared with estrogen alone.  This large multicenter study therefore suggests
    that there is a dramatic difference between the effects of bioidentical
    progesterone versus synthetic progestins on breast cancer risk.

    Missmer SA, Eliassen AH, Barbieri RL, Hankinson SE.
    Endogenous estrogen, androgen, and progesterone concentrations and
    breast cancer risk among postmenopausal women.  J Natl Cancer Inst 2004; 96
    (24):1856-65.  
    Blood progesterone levels were found not to be related to breast cancer risk in
    this first study to investigate this in postmenopausal women. The occurrence of
    progesterone receptor positive tumors was the tumor type most strongly affected
    by all the circulating steroid hormones measured except for progesterone.  Higher
    levels of endogenous estrogens and androgens were significantly correlated with
    increasing breast cancer incidence.  This suggests that circulating natural
    progesterone does not increase breast cancer risk.

  • Merilee
    Merilee Member Posts: 734
    edited June 2011

    Thanks for posting that Joy, information is always good to read.

  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011

    Ok, now i understand ! u,re talking about bio-identical hormone replacement as opposed to the hard core synthetic version which my cousin got. Will also have to research this, sigh !!! I need to spend 24-7 at the computer to wrap my brains around this damn bc.



    MBJ, same situation here, totally burned out from job before dx. How do u go about rebuilding , anything special u take for the adrenals ? Thanks sweetie :)

  • pip57
    pip57 Member Posts: 7,080
    edited June 2011

    Kira,

    My daughter's cancer was due to a mutation of the P53 gene.  I was tested and the results say that there is a slight variance but not one that is considered important in terms of developing cancer.  I read that to add "yet".   There is so much we don't know 'yet'.

    I don't know what the protocol would be in the US, but I was given the genetic testing because of family history and specifically because of my daughter's rare and aggressive cancer.  It is an expensive test and was sent to Harvard to be done.  (I did not have to incur any costs) 

  • mollyann
    mollyann Member Posts: 148
    edited June 2011

    Dear Luan,

    MBJ has a really good doctor. She will have good info. I always love it when she posts her list!

    From my own research the best way to test adrenal status is through saliva testing. ZRT labs is recommended for that. Then the good doctors use isocort or low dose cortisone until the adrenals repair. Some start out with a kind of licorice if the adrenals are not too bad. Natural progesterone also can boost the adrenals and thyroid. I will try to find the website with recordings from the best known patient expert on this. She has been doing this research for years and interacting with other patients.

    After my last job (total burnout stress, just like you guys Frown) I was prescribed 2 grams of Vitamin C and 500 mg of pantothenic acid (Vitamin B5) by my integrative-minded family doc. That did help some. He didn't know about the special licorice tho.

     Research does take some chasing down of leads but then all the information seems to come together. Smile 

  • Merilee
    Merilee Member Posts: 734
    edited June 2011

    What special licorice are you guys talking about?

  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011

    Pip, when I met the genetic team and brought up the P53 gene, they pretended they did not know what I was talking about, felt like a fool, but glad you could get it.....

    Molly, thanks a mile for the invaluable info.  Just went to my third family physician in that many years, and she looked at me as if I was right out of the mental hospital when I asked her to test my vit. D.  Guess I'll be shopping for the fourth one Yell  I would personally stay away from licorice as it is pretty potent in phytoestrogens for a hormonal gal like me

  • Luna5
    Luna5 Member Posts: 532
    edited June 2011

    Mollyann...Thank you...I have checked it there and it looks like the one ingredient they have a cancer warning on is Retinyle Palmate (Vit A)...so I may return the one with that ingredient and keep the one with fewer ingredients.

    I know that this and the cosmeticdatabase,com  sites sometimes only have limited info on each product 

    Since I know so many on this thread have done tons of research .. I was hoping that if someone else knows of a reason not to use DMAE  that they will let us know.

  • mollyann
    mollyann Member Posts: 148
    edited June 2011

    Merilee,

    The licorice form is spelled oddly. I will find out for you this week the exact kind as I don't want to get it wrong.

    Luan, somebody posted a study here a year or two showing that breast cancer patients consuming a high phytoestrogen diet didn't do any worse than those on a low phytoestrogen diet. I should have bookmarked the study at the time. Famous last words!!!

  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011

    Molly, after reading this book with very extensive background research, it would take a lot to convince me about phytoestrogens. "What your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Help Save Your Life"  Dr. John Lee and Dr. Zava, PhD (biochemist, research scientist and internationally known speaker and leading expert in the field of hormone health)

    Susan, you're an angel !!!!!  Just hope he takes new patients, you know how hard that is to find.  The ones left are highly non recommendable, like the one who told me not to worry when I showed him my lump, he told me it was an abscess.  What a jerk !  I fired him on the spot !

  • kira1234
    kira1234 Member Posts: 754
    edited June 2011

    I'm not sure but I think the p53 was done by the oncotype test people. In my case it says p53 is 4% positive. I just wish I new what that means.

  • pip57
    pip57 Member Posts: 7,080
    edited June 2011

    I don't know what the 4% means.  Does it refer to mutations at all?

     Mine say '"negative for mutations, except for a silent change called a polymorphism.  This change is not thought to be responsible for your personal and family history of cancer."

  • kira1234
    kira1234 Member Posts: 754
    edited June 2011

    pip57, It doesn't say anything other than being positive. I'm wondering if it means it's 4% mutated. It would be helpful if they stated if it was mutated or not.

  • pip57
    pip57 Member Posts: 7,080
    edited June 2011

    Try typing in some of the exact words on google.  Maybe it will come up with some explanation.

  • vivre
    vivre Member Posts: 881
    edited July 2012

    Our first line of defense against disease is the digestive system. That is why eating well is so important. Our second defense is our immune system. That is why keeping our immune system strong with quality supplements, and with controlling toxins and inflammations are important. When these two systems break down or are overstressed, cells can suffer DNA damage, which causes disease to develop. That is why reducing free radicals is so important. These free radicals displace important elements of a damaged cell and allow disease to take root. Healthy says will fight off free radicals.

    The reason stress is a leading cause of disease is that it creates havoc with our digestion, and with our eating habits and suppresses the immune system. That is why it is essential we reduce stress. Happy people rarely get cancer. Happy people who are surrounded by happy people rarely get cancer. We need to detoxify our bodies and our lives of all the stress we can. If we cannot eliminate certain people from our lives, because we love them in spite of ourselves (ie, KIDS, lol), we need to learn how to let go of all the stress. That is why I am such a huge proponent of walking and also why I refuse to get into any bickering that is rampant on this website. If people do not agree with me, so be it. I just move right along. I have been so much happier since I have learned how to ignore negative people.

    As for EWG and skin deep-please do some research on these groups, which are run by the same people. They are not reliable sources of information. I have not been able to find out who is doing their "research". All I can find out is that they are an arm of the political laundering TIDES foundation  which was started by hedgefund billionaire and puppetmaster George Soros and people with dubious backgrounds. Their purpose is to make money so they can buy off polititians.

    If anyone wants great info on beauty products, read Bea Kinnears book "Your Skin and You". You Canadians can probably get it cheaper than we can in the US because Bea is Canadian. I have correspended with Bea, and she has really done her homework. She separates a lot of fact from myth when it comes to skin care. I am not sure I agree with everything she says, but I have learned a lot about how there is not a lot of proof for some of the scare tactics that groups like the EWG put out there for products that are not actually carcinogenic. Where she and I disagree is that she believes we all need sunscreen. I do not use it because my cells are so nourished now with my diet and supplements. People often comment on how great my skin looks. I just want to add a little to my skin as possible. I stick strickly to coconut oil and Usana's Sense skincare line. I still have not found a make up I can trust. I have spent the last few days biking and gardening in full sun and have no sunburn. All that fish oil and Usana's essentials are like skin armor for me.

    Luna-if you want to call me, I can read you what Bea says about DMAE. She does not recommend it. I do not want to type a whole chapter.

  • Luna5
    Luna5 Member Posts: 532
    edited June 2011

    Vivre...What do you think of Dr. Perricone...he seems to highly recommend DMAE.  I'm still researching.  Can't call you from where I am vacationing...no phone reception...but there is internet so maybe I can download Bea Kinnears book on my Kindle... Thanks for the tip

    .

  • corian68
    corian68 Member Posts: 86
    edited June 2011

    I use Dr. Perricone....love his products!!!!!!!!!!

  • corian68
    corian68 Member Posts: 86
    edited June 2011

    Kira1234

    I would gues it means that your suppressor gene is somewhat mutated? 

  • corian68
    corian68 Member Posts: 86
    edited June 2011

    I was just reading about the percentages and 4% is a low mutation . I have read a lot on P53 & Selenium. Selenium rapidly activates P53 pathways. I take 100 mcg's per day. It's in a multi with A, C, E, and Zinc too.I got it from my ND. it's called Carlson :)

  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011

    Kira, sweetie, i would try to not worry about it. First, 4% sounds very small, am betting that if i got tested i might not fare as well, but they are not testing me for lack of pertinence. Genetic testing is new and it certainly has its limits. Pip,s case is different because of her daughter,s aggressive cancer, and she tested neg. I would try not to worry as i am sure u have enough on your plate as it is, just like the rest of us. Have a wonderful day :)) P.S. Corian has excellent advice plus selenium is vital to thyroid

  • rgiuff
    rgiuff Member Posts: 339
    edited June 2011

    Sherry, vaginal discharge, not dryness, is the norm with tamoxifen.  After hot flashes, I think it's the most common and consistent side effect.  As far as the sex drive goes, I'd be happy in your shoes, because it seems to have suppressed mine.

    As far as progesterone goes, a year or two ago, there were lots of postings on this Natural Girls forum about how progesterone suppresses cell proliferation, while estrogen stimulates it, which would mean that bioidentical progesterone is good for breast cancer and being PR+ could mean that the progesterone helps the cancer not to be as aggressive.  Tumors that are ER+, PR- don't do as well as those that are ER+/PR+.  With everything I've read about it, it makes sense to me that having enough progesterone would be good for breast cancer. 

    Now if somebody would do a good study on comparing the synthetic progestins to the bioidentical progesterone, maybe it could be proven to the medical community that there is a difference.

  • lucy88
    lucy88 Member Posts: 100
    edited June 2011

    Rose, transdermal hormone studies of bioidenticals have been done in Europe where bioidenticals are used more. PM me if you want the info on studies. Most people have already made up their mind so it isn't productive debating the subject on the group. 

    If a doctor says all estrogens are alike or that progestins and progesterones are alike, you know you are dealing with someone who hasn't read anything and is just parroting the erroneous scuttlebutt out there. They don't have time to read much.

    We have two PhD scientists, one a reknown progesterone author, in our local study group. So we have read most everything on the subject.

  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011
    Lucy, you would save me a lot of trouble if you shared the info you're offering Rose. I just don't know where to start with this issue.  All I know is that while on Tamox, my hormones must be going crazy, am even getting lots of periods-like cramping. Many thanks in advance !
  • [Deleted User]
    [Deleted User] Member Posts: 323
    edited June 2011

    Corian and Kira, check this out : http://aiocm.org/?p=244

    Hi all, re phytoestrogens, I continue to err on the side of caution:

    "Phytoestrogens may serve as chemopreventive agents while at the same time being capable of promoting growth in estrogen receptor positive cancer cell lines. Furthermore, they may exert their estrogenic influence through receptor-dependent and/or receptor-independent mechanisms. These findings have led to speculation that phytoestrogen intake might be ill advised for patients at an increased risk for hormone-dependent cancers, cancer patients, or cancer survivors."

    http://www.ncbi.nlm.nih.gov/pubmed/15035899