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Breastcancer.org Podcasts: Experts discuss research & issues

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  • moderators
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    edited February 2019
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    Fashion Statements With Sheila McGlown: Metastatic Breast Cancer on the AnaOno Runway

    February 11, 2019

    Mcglown sheila

    Sheila McGlown talks about body positivity, choosing to be bald, and what walking in the AnaOno Fashion Week show means to her.


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  • moderators
    moderators Posts: 8,091
    edited February 2019
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    Fashion Statements With Susan Sullivan Danenberger: Metastatic Breast Cancer on the Runway

    February 11, 2019

    Sullivan danenberger susan small

    Susan Sullivan Danenberger talks about her experience with metastatic breast cancer, reconstruction, and what it's like to walk in the AnaOno fashion show.

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  • moderators
    moderators Posts: 8,091
    edited March 2019
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    Exercise for People Diagnosed With Metastatic Breast Cancer

    February 22, 2019

    Mansfield sami small

    Sami Mansfield started her career as a cancer exercise specialist in 2003. Since being inspired by coaching her first client who had been diagnosed with cancer 15 years ago, her career has been dedicated to helping people with cancer — any type and any stage — live as well as possible. Sami's experience encompasses work in both community- and hospital-based cancer centers, non-profit organizations, developing and consulting on clinical trials, and as a speaker presenting to both patients and healthcare professionals. She is a certified cancer exercise trainer and CrossFit Level 1 coach with extensive exercise and nutrition experience.

    Listen to the podcast to hear Sami discuss:

    • how attainable "exercise snacks" can help people start exercising
    • three exercises anyone can do safely at home
    • whether people with metastatic disease should "feel the burn" when they exercise
    • how to talk to your oncologist about exercise

    Running time: 32:05

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  • moderators
    moderators Posts: 8,091
    edited March 2019
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    Becoming Your Own Advocate
    March 1, 2019

    Kimberly jewett 2 small

    Kimberly Jewett is a two-time breast cancer survivor, passionate advocate, consultant, and CEO of her Chicago firm at kimberlyjewett.com. Kim was first diagnosed with breast cancer when she was 31 years old; her second diagnosis came four years later at age 35. Her treatments included surgeries, chemotherapy, and radiation, all while being a mother to two young children. Currently, she has no evidence of disease. Kim attributes her survivorship to her faith, strength, hope, and passion. She has recently published a memoir about her breast cancer experience titled STRONG(ER+): Becoming My Own Best Advocate and Discovering My Purpose. By sharing her story as a two-time cancer survivor, Kim aims to empower others to be advocates in their healthcare decisions.

    Listen to the podcast to hear Kim discuss:

    • what it means to be your own advocate
    • how being an advocate gives you some control over situations you may feel you have no control over
    • 10 steps you can take to help you be your own best advocate

    Running time: 21:34

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  • moderators
    moderators Posts: 8,091
    edited March 2019
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    Reiki: What It Is and How It Helps People With Cancer

    March 8, 2019

    Dupree beth small

    Beth Baughman DuPree is a board-certified general surgeon specializing in diseases of the breast, with additional board certification in integrative medicine. She is also a master level Reiki practitioner. Dr. DuPree is part of the Sedona Breast Care Clinic of the Northern Arizona Healthcare System.

    Dr. DuPree earned her medical degree from Hahnemann University in Philadelphia and her undergraduate degrees in behavioral neuroscience and the history and philosophy of science at the University of Pittsburgh.

    Her first book, The Healing Consciousness: A Doctor's Journey to Healing, was released in 2006 to excellent reviews by Christiane Northrup, M.D., and Bernie Siegel, M.D, among other well-known experts in the women's health field. Her numerous honors include the Clara Barton Humanitarian Award from the American Red Cross for her ongoing contributions to the treatment of breast cancer. She was selected by her peers for Philadelphia Magazine's TOP DOCS in Surgery in 2016 and 2017. She serves on the advisory board for Breastcancer.org and often hosts live chats and podcasts on current breast cancer issues.

    Listen to the podcast to hear Dr. DuPree explain:

    • what Reiki is and she uses it in her practice
    • what happens during a typical Reiki session
    • the benefits of Reiki for people diagnosed with cancer
    • three things you should know before trying Reiki

    Running time: 37:28

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  • moderators
    moderators Posts: 8,091
    edited March 2019
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    Low White Blood Cell Counts and Infection Risk

    March 14, 2019

    Brian wojciechowski md final 6340

    Brian Wojciechowski, M.D., practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and Lankenau Medical Center. Dr. Wojciechowski is a sought-after speaker on the topics of medical ethics and the biology of cancer.

    Listen to the podcast to hear Dr. Wojciechowski explain:

    • the different types of white blood cells and what they do in the body
    • how chemotherapy and targeted therapy medicines lower white blood cell counts
    • why low white blood cell counts raise the risk of infection
    • how doctors monitor white blood cell counts
    • symptoms of infection to watch out for
    • steps you can take during chemotherapy to keep your risk of infection as low as it can be

    Running time: 12:19

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  • moderators
    moderators Posts: 8,091
    edited April 2019
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    Managing Constipation

    April 5, 2019

    Chey preferred small

    William Chey, M.D., is professor of internal medicine and professor of nutrition at the University of Michigan, where he leads the Functional Gastrointestinal Disorders Research Group. His research interests include diagnosis and treatment of irritable bowel syndrome, constipation, fecal incontinence, gastroesophageal reflux disease, and H. pylori infection. During his 30 years of treating people with constipation, Dr. Chey has written more than 300 manuscripts, reviews, and book chapters. He received his medical degree from Emory University and completed a fellowship in gastroenterology at the University of Michigan.

    In this podcast on constipation, Dr. Chey discusses risk factors for constipation, how to manage constipation, as well as his favorite constipation joke. Listen to the podcast to hear him explain:

    • why he recommends an integrated, holistic approach to managing constipation
    • why patients need to overcome any embarrassment they have about constipation and be their own advocate for treatment
    • the steps he recommends when treating constipation

    Running time: 26:23

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  • moderators
    moderators Posts: 8,091
    edited April 2019
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    Depression and Suicidal Thoughts After a Cancer Diagnosis

    April 26, 2019

    Rosenstein donald small

    Dr. Donald Rosenstein is a professor of psychiatry and director of the Lineberger Comprehensive Cancer Center Comprehensive Cancer Support Program at the University of North Carolina at Chapel Hill.

    Dr. Rosenstein's research focuses on the areas where medicine and psychiatry meet. His research interests include assessing and managing suicide in the medical setting and psychosocial support for patients facing cancer. In 2017, Dr. Rosenstein was elected president of the American Psychosocial Oncology Society. He is also co-author of The Group: Seven Widowed Fathers Reimagine Life, which details the challenges and triumphs of seven men who raised young children after their wives died.

    In this podcast on depression and suicidal thoughts after a cancer diagnosis, Dr. Rosenstein talks about what major depression can feel like, as well as risk factors for depression. Listen to the podcast to hear him discuss:

    • what we know about depression as a side effect of tamoxifen
    • signs that you may need to see a doctor for depression
    • treatments for depression
    • depression in the context of breast cancer and why people should not suffer with depression in silence

    Running time: 25:44

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  • moderators
    moderators Posts: 8,091
    edited May 2019
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    Body Fat and Weight Loss

    May 8, 2019

    Mariesavard small

    Marie Savard, M.D., is a doctor, educator, and former ABC News medical contributor. She is the founder of the Savard System for managing and controlling your healthcare. Dr. Savard is the author of five books, focusing on women's health and wellness.

    A native of Philadelphia, she received a bachelor's degree in nursing and a medical degree from the University of Pennsylvania. She formerly served as the director of the Center for Women's Health at the Medical College of Pennsylvania, technical adviser to the United Nations' Fourth World Conference on Women in Beijing, adviser to the American Board of Internal Medicine Subcommittee on Clinical Competency in Women's Health, health columnist for Woman's Day magazine, and senior medical consultant to Lifetime Television's "Strong Medicine."

    In this podcast on body fat, weight, and weight loss, Dr. Savard explains what women, especially postmenopausal women, can do to prevent weight gain and lose some pounds that may have been gained. Listen to the podcast to hear her explain:

    • why women tend to gain weight and change shape after menopause
    • steps you can take to reduce the risk of gaining weight after menopause
    • the top four things she recommends to a woman who wants to lose weight

    Running time: 23:30

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  • moderators
    moderators Posts: 8,091
    edited May 2019
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    What Is Mindfulness?

    May 24, 2019

    Romano laura small

    Laura Cohen Romano is director of spiritual care and mindfulness for the Einstein Healthcare Network. She first came to Einstein in 2009 as director of chaplaincy, language and culture, and volunteer services. Laura began her own journey with meditation 25 years ago, and with evidence-based mindfulness meditation and practices 12 years ago. Following her growing passion to share the many benefits of mindfulness, she pursued training as a mindfulness teacher, first through teacher training at the Mindfulness Institute at the Jefferson Myrna-Brind Center for Integrative Medicine, and then receiving her teacher qualification through the University of California-San Diego School of Medicine Center for Mindfulness.

    Mindfulness and/or mindfulness meditation can be intimidating to many people. They're not sure if they're doing it correctly — or at all. People worry they can't completely clear their minds and become frustrated. While mindfulness can't make cancer or other chronic illness go away, it can help people with a disease have better quality of life by easing pain, stress, and worry.

    Listen to the podcast to hear Laura explain:

    • exactly what mindfulness and mindfulness meditation are
    • where mindfulness started
    • some common myths about mindfulness

    For the last 5 minutes of the podcast, Laura leads a short, guided mindfulness meditation so everyone can experience mindfulness.

    Running time: 36:37

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    ASCO 2019: Diet, Exercise, and Breast Cancer Outcomes

    June 1, 2019

    Karen basen engquist.jpg.resize.405.575.high

    Dr. Karen Basen-Engquist is professor of behavioral science and director of the Center for Energy Balance in Cancer Prevention and Survivorship at the University of Texas MD Anderson Cancer Center.

    Dr. Basen-Engquist's research focuses on cancer survivors and how health behavior interventions can reduce the severity of late-term side effects, improve physical function, optimize quality of life, and reduce the risk of chronic diseases. She also studies ways to help people make behavior changes and ways to assess symptoms and behavior in cancer patients and survivors.

    Listen to the podcast to hear Dr. Basen-Engquist talk about:

    • how to talk about diet and exercise with your doctor
    • why exercise and maintaining a healthy weight should be part of every person's long-term cancer care
    • how people who are feeling overwhelmed about having to make a lot of diet, weight, and exercise changes can start slowly to improve their health

    Running time: 14:27

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    Metabolite Markers -- Heard in the Halls: Voices From the 2019 American Society of Clinical Oncology Annual Meeting

    June 1, 2019

    Oday liz

    Dr. Liz O'Day talks about a test her company is developing that uses metabolites in blood to assess whether a person with metastatic breast cancer will respond to CDK4/6 inhibitors.

    Running time: 3:35

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    Live by Living -- Heard in the Halls: Voices From the 2019 American Society of Clinical Oncology Annual Meeting

    June 1, 2019

    Miller dan

    Dan Miller, founder of Live by Living, explains how the organization offers free outdoor experiences to people diagnosed with cancer and their caregivers.

    Running time: 2:34

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    ASCO 2019: The BWEL Study: Diet and Exercise in Women Diagnosed With Breast Cancer

    June 2, 2019

    Ligibel jennifer

    Dr. Jennifer Ligibel is associate professor of medicine at Harvard Medical School who treats breast cancer at the Dana-Farber Cancer Institute. Dr. Ligibel's research looks at the relationship between diet and exercise and breast cancer risk and prognosis. Her current project is the Breast Cancer Weight Loss (BWEL) study, which is looking at connections between exercise, diet, weight management, sleep, and health and wellness outcomes in women being treated for breast cancer.

    Listen to the podcast to hear Dr. Ligibel talk about:

    • the progress of the BWEL study so far
    • how the BWEL study is different from other studies that looked at low-fat diets and breast cancer
    • why the BWEL study wants to examine methods that work best to help women diagnosed with breast cancer lose weight and exercise more

    Running time: 16:44

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    ASCO 2019: Right to Try Legislation and Why Clinical Trial Entry Criteria Need to Change

    June 2, 2019

    Shanahan kelly

    Dr. Kelly Shanahan describes herself as a mother, wife, daughter, doctor, and woman living with metastatic breast cancer. Neuropathy from breast cancer treatment forced her to retire from her OB/GYN practice. She now works tirelessly as an independent metastatic breast cancer advocate. Dr. Shanahan was part of a panel on Right to Try Legislation at the 2019 American Society of Clinical Oncology Annual Meeting. In this podcast, she explains Right to Try and Compassionate Use legislation and why she thinks the real answer is changing the criteria for enrolling in clinical trials.

    Listen to the podcast to hear Dr. Shanahan talk about:

    • why she thinks Right to Try legislation is flawed
    • how the common criteria for entering a clinical trial exclude a majority of people diagnosed with metastatic disease and how trials can be changed
    • how she would proceed if her disease progressed and she didn't meet the eligibility criteria for an appropriate clinical trial

    Running time: 25:12

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    Can a Low-Fat Diet Reduce the Risk of Dying From Breast Cancer? -- Heard in the Halls: Voices from the 2019 American Society of Clinical Oncology Annual Meeting

    June 2, 2019

    Chlebowski

    Dr. Rowan Chlebowski, of the Los Angeles Biomedical Research Institute, explains the results of the latest analysis of data from the Women's Health Initiative.

    Running time: 2:50

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    ASCO 2019: Women Don't Need Reminders to Take Aromatase Inhibitors, They Need Better Treatments for Side Effects

    June 3, 2019

    Hershman dawn

    A member of the Breastcancer.org Professional Advisory Board, Dr. Dawn Hershman leads the Breast Cancer Program at the Herbert Irving Comprehensive Cancer Center at Columbia University, where she is professor of medicine and epidemiology. Dr. Hershman is a nationally recognized expert in breast cancer treatment, prevention, and survivorship.

    At this ASCO annual meeting, Dr. Hershman presented results from a study looking at whether text messaging could increase the number of women who stick to their aromatase inhibitor treatment plans.

    Listen to the podcast to hear Dr. Hershman talk about:

    • the background of the study
    • the study results, which showed no difference in treatment adherence between women who received text messages and women who didn't
    • what future research needs to do to better help women stick to their aromatase inhibitor treatment plans

    Running time: 9:37

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  • moderators
    moderators Posts: 8,091
    edited June 2019
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    Top Metastatic Breast Cancer Research at ASCO 2019

    June 4, 2019

    Dickler maura

    Dr. Maura Dickler, vice president of oncology late phase development for Eli Lilly and Company, offers insights on some of the most interesting research on metastatic breast cancer presented at the 2019 American Society of Clinical Oncology Annual Meeting.

    Listen to the podcast to hear Dr. Dickler explain:

    • results from the IMpassion 130 trial looking at Tecentriq (chemical name: atezolizumab) and Abraxane (chemical name: albumin-bound or nab-paclitaxel) to treat metastatic triple-negative breast cancer
    • results from the Young-PEARL trial studying Ibrance (chemical name: palbociclib) and Aromasin (chemical name: exemestane) along with ovarian suppression to treat premenopausal women diagnosed with hormone-receptor-positive metastatic breast cancer
    • overall survival results from the MONALEESA-7 trial, which examined using Kisqali (chemical name: ribociclib) and hormonal therapy to treat premenopausal women diagnosed with hormone-receptor-positive, HER2-negative advanced-stage breast cancer

    Running time: 9:30

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    moderators Posts: 8,091
    edited June 2019
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    Telling Your Breast Cancer Story With Art Therapy

    June 21, 2019

    Mcleod estevez stephanie small

    Stephanie McLeod-Estevez is a licensed clinical professional counselor and art therapist with 15 years of clinical expertise in treating anxiety, depression, and trauma. Stephanie also is a breast cancer survivor. She started her company, Creative Transformations, in 2016 to provide information, tools, and services to people diagnosed with cancer to enhance their emotional health and wellness. Her writing has been published in Wildfire, Coping with Cancer, and Breast Cancer Wellness.

    In this podcast on art therapy, Stephanie explains how people diagnosed with cancer can use it to heal emotionally, physically, and spiritually.

    Listen to the podcast to hear Stephanie discuss:

    • her own breast cancer journey and how that influenced her career
    • the process of art therapy and its benefits
    • how to find a reputable art therapist

    Running time: 26:28

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  • moderators
    moderators Posts: 8,091
    edited July 2019
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    Cancer-Related Fatigue: What It Is and How to Manage It

    July 5, 2019

    Khanna ashish

    Ashish Khanna, M.D., is a physical medicine and rehabilitation specialist at the Kessler Institute for Rehabilitation and part of the ReVital Cancer Rehabilitation Program. Dr. Khanna completed his residency in physical medicine and rehabilitation at the Kingsbrook Jewish Rehabilitation Institute in Brooklyn, NY, where he became interested in cancer rehabilitation early on. He completed his fellowship subspecialization in cancer rehabilitation at Medstar Georgetown University and the National Rehabilitation Hospital in Washington, DC. He specializes in the treatment of people who have pain or functional issues as a result of cancer or cancer treatments, including people who have been diagnosed with breast cancer. This includes pain, shoulder issues, fatigue, joint pain from aromatase inhibitors, and other issues. He has lectured at numerous international conferences, has published peer-reviewed research on a variety of related topics, and is the co-author of an upcoming book on cancer rehabilitation.

    Listen to the podcast to hear Dr. Khanna explain:

    • how cancer-related fatigue is different from other fatigue
    • the link between inflammation and fatigue
    • why exercise is the best remedy for fatigue
    • steps you can take if you think you have cancer-related fatigue

    Running time: 25:22

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  • moderators
    moderators Posts: 8,091
    edited July 2019
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    What My Patients Are Asking: Explain the New Breast Cancer Staging Guidelines

    July 19, 2019

    Brian wojciechowski md final 6340

    Brian Wojciechowski, M.D., practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer Hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and Lankenau Medical Center. Dr. Wojciechowski is a sought-after speaker on the topics of medical ethics and the biology of cancer.

    In 2018, the American Joint Committee on Cancer, commonly called the AJCC, updated breast cancer staging guidelines to add other information to how a cancer's stage is determined. This has made determining the stage of a breast cancer more complex, but also more accurate.

    Listen to the podcast to hear Dr. Wojciechowski explain:

    • what the T, N, and M parts of the staging system mean
    • how the new characteristics added to the staging system in 2018 — cancer grade, estrogen receptor status, progesterone receptor status, HER2 receptor status, and Oncotype DX Recurrence Score — affect a breast cancer's stage
    • how a cancer that might have been stage IIIA in the past might now be stage IB

    Running time: 16:54

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  • moderators
    moderators Posts: 8,091
    edited August 2019
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    Breast Implant Illness: What Do We Know Right Now?

    August 2, 2019

    Dellacroce suit

    Dr. Frank DellaCroce, or "Dr. D" as he has come to be known, is a founding partner of the Center for Restorative Breast Surgery and St. Charles Surgical Hospital in New Orleans. Board-certified in plastic surgery, Dr. D has performed thousands of reconstructive procedures, both for women diagnosed with breast cancer and women at high risk of the disease who choose to have prophylactic breast removal. He is a Fellow of the American College of Surgeons and a member of numerous professional societies, including the American Society of Plastic and Reconstructive Surgery, the American Society for Reconstructive Microsurgery, and the World Society for Reconstructive Microsurgery. He also has been named one of the "Best Doctors in America."

    In this podcast, Dr. DellaCroce discusses illness linked to breast implants, the Allergan textured implant recall, as well as how he is counseling his patients.

    Listen to the podcast to hear Dr. DellaCroce discuss:

    • the differences between textured and smooth implants, as well as the differences between silicone-filled and saline-filled implants and the theories as to why textured and silicone implants are linked to disease
    • what breast implant-associated anaplastic large-cell lymphoma is and how it is treated
    • what to do if you have an implant and are concerned

    Running time: 44:29

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  • moderators
    moderators Posts: 8,091
    edited August 2019
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    What My Patients Are Asking: The Difference Between 2D and 3D Mammograms

    August 16, 2019

    Brian wojciechowski md final 6340

    Brian Wojciechowski, M.D., practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and Lankenau Medical Center. Dr. Wojciechowski is a sought-after speaker on the topics of medical ethics and the biology of cancer.

    A recent study found that the number of women having 3D mammograms has increased dramatically in the last four years. Still, 3D mammograms are not available everywhere.

    Listen to the podcast to hear Dr. Wojciechowski explain:

    • the difference between 2D and 3D mammograms
    • why 3D mammograms are a standard of care, but not the standard of care
    • how to find a center that offers 3D mammography, if you decide you would like one

    Running time: 11:07

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  • moderators
    moderators Posts: 8,091
    edited September 2019
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    What My Patients Are Asking: Can Dog Deworming Medicine Treat Breast Cancer?

    August 30, 2019

    Brian wojciechowski md final 6340

    Brian Wojciechowski, M.D., practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and Lankenau Medical Center. Dr. Wojciechowski is a sought-after speaker on the topics of medical ethics and the biology of cancer.

    Blogs and popular media have discussed using fenbendazole (brand names: Panacure, Safe-Guard), a drug used to deworm dogs, to treat cancer. While some studies on cells in petri dishes and in mice suggest that fenbendazole might have anti-cancer properties, no studies have been done in people and it's not clear what side effects it may cause or what the optimal dose might be.

    Listen to the podcast to hear Dr. Wojciechowski talk about:

    • the type of drug fenbendazole is and how it might kill cancer cells
    • the studies in petri dishes and mice on fenbendazole that have been done so far
    • what he tells his patients when they ask about fenbendazole

    Running time: 14:58

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  • moderators
    moderators Posts: 8,091
    edited October 2019
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    The Think Before You Pink Project

    September 20, 2019

    Jaggar karuna small

    Karuna Jaggar has been executive director of Breast Cancer Action since 2011 and has a lifelong commitment to social justice. Throughout her 15-year career in nonprofit leadership, her work has focused on women's rights and on eliminating socioeconomic inequities. Jaggar began her career working with women's microenterprises internationally and in the United States, providing self-employment and business training, funding and support for low-income women. Prior to joining Breast Cancer Action, Jaggar was executive director at the Women's Initiative for Self Employment. She has served on the Board of the California Association of Microenterprise Opportunity, where she chaired the Policy Committee. She holds a master's degree in economic geography from the University of California-Berkeley and received her bachelor's degree in philosophy from Smith College.

    With Breast Cancer Awareness Month upon us, Karuna joins us to talk about the Think Before You Pink project, including its history and goals.

    Listen to the podcast to hear Karuna talk about:

    • how the Think Before You Pink campaign started
    • how she defines "pink washing"
    • reactions to the campaign
    • four questions Breast Cancer Action asks people to consider before buying anything with a pink ribbon on it

    Running time: 28:46

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  • moderators
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    edited October 2019
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    Where Are We With Immunotherapy for Breast Cancer? ESMO 2019 Coverage

    September 27, 2019

    Litton jennifer

    Dr. Jennifer Litton is a board certified medical oncologist and professor of breast medical oncology at the University of Texas MD Anderson Cancer Center in Houston, where she is chief of the Section of Clinical Research and Drug Development for Breast Cancer. She also is a member of the Breast Immuno-Oncology Task Force of the National Cancer Institute.

    At the European Society for Medical Oncology 2019 Congress, she presented information on a study she's leading, looking at combining a new type of immunotherapy with a traditional chemotherapy medicine. She joined us to talk about current immunotherapy research for breast cancer in general as well as what is specifically being presented at the congress.

    Listen to the podcast to hear Dr. Litton discuss:

    • why immunotherapy medicines to treat breast cancer will likely be used with another type of therapy, such as chemotherapy or radiation therapy
    • the difference between a "hot" and "cold" tumor and why that is important for immunotherapy
    • other biomarkers besides PD-L1 that may help doctors decided if an immunotherapy medicine will work

    Running time: 16:50

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  • moderators
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    edited October 2019
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    People Satisfied With Decision to Use Scalp Cooling, Even If It's Not Effective -- Heard in the Halls: Voices From ESMO 2019

    September 28, 2019

    Murphy

    Dr. Conleth Murphy, an oncologist at Bon Secours Cork Cancer Center in Ireland, discusses his research on scalp cooling in people being treated with chemotherapy for cancer.

    Running time: 2:58

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  • moderators
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    edited October 2019
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    Immunotherapy to Treat Metastatic HER2-Positive Breast Cancer: ESMO 2019 Coverage

    September 29, 2019

    Emens leisha

    Dr. Leisha Emens is professor of medicine in hematology/oncology at the University of Pittsburgh Hillman Cancer Center. She is also co-leader of the Hillman Cancer Immunology and Immunotherapy Program and director of translational immunotherapy for the Women's Cancer Research Center. She is internationally recognized for her work in breast cancer immunotherapy.

    At the European Society for Medical Oncology 2019 Congress, she presented overall survival results from the KATE2 study, which compared using the combination of Tecentriq, also called atezolizumab, and Kadcyla, also called T-DM1, to Kadcyla alone to treat HER2-positive metastatic breast cancer that had grown while being treated with Herceptin and chemotherapy.

    Listen to the podcast to hear Dr. Emens discuss:

    • the design of the KATE2 study
    • why the study is encouraging, even though it didn't meet its primary endpoint
    • what the results mean for people diagnosed with HER2-positive metastatic breast cancer
    • her advice to people diagnosed with breast cancer who are interested in immunotherapy

    Running time: 10:04

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    edited October 2019
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    Immunotherapy Keytruda for Early-Stage Triple-Negative Breast Cancer: Better pCR and Lower Recurrence Rates: ESMO 2019 Coverage

    September 29, 2019

    Schmid peter

    Dr. Peter Schmid is chair in cancer medicine at Barts Cancer Institute, Queen Mary University London and also serves as clinical director of the Breast Cancer Centre at the St. Bartholomew Cancer Centre and honorary consultant medical oncologist at Barts Hospital. His research focuses on breast cancer, cancer immune therapy, and early drug development.

    At the European Society for Medical Oncology 2019 Congress, he presented results from the KEYNOTE-522 study showing that the combination of the immunotherapy Keytruda (chemical name: pembrolizumab) and chemotherapy before surgery to remove early-stage triple-negative breast cancer led to a better pathologic complete response than chemotherapy alone. This is the first phase III study using immunotherapy to treat early-stage breast cancer.

    Listen to the podcast to hear Dr. Schmid discuss:

    • the design of the KEYNOTE-522 study
    • side effects related to both chemotherapy and Keytruda
    • what these results mean for patients

    Running time: 9:27

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    edited October 2019
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    "CDK4/6 Inhibitor Plus Hormonal Therapy Should Be First Treatment for Metastatic Hormone-Receptor-Positive, HER2-Negative Breast Cancer" ESMO 2019 Coverage

    September 29, 2019

    Slamon dennis

    Dr. Dennis Slamon is professor of medicine and executive vice chair for research for the UCLA Department of Medicine. He also serves as director of clinical/translational research and director of the Revlon/UCLA Women's Cancer Research Program at the Jonsson Comprehensive Cancer Center at UCLA. He is probably best known for doing the laboratory and clinical research that led to the development of Herceptin, the first medicine to specifically treat HER2-positive breast cancer. Dr. Slamon has won numerous awards for his research. Earlier this month, he received the 2019 Lasker Award for clinical medical research for his groundbreaking work on Herceptin.

    At the European Society for Medical Oncology 2019 Congress, he presented overall survival results from the MONALEESA-3 study, looking at using the CDK4/6 inhibitor Kisqali (chemical name: ribociclib) plus the hormonal therapy Faslodex (chemical name: fulvestrant) to treat advanced-stage, hormone-receptor-positive, HER2-negative breast cancer in postmenopausal women.

    Listen to the podcast to hear Dr. Slamon explain:

    • the background of the MONALEESA-3 study
    • how much adding Kisqali to Faslodex improved overall survival compared to Faslodex alone
    • treatment side effects seen in the study
    • what the results mean for people diagnosed with metastatic hormone-receptor-positive, HER2-negative breast cancer

    Running time: 9:10

    Listen now or read the transcript.