Single Hormone Receptor Positive -> ER+/PR-/HER2-
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@walsr014 I’ve not heard a verbatim statement that most PR- are in the clear after 5 years. After my surgery, chemo, and radiation, my probability of recurrence in 9 years is 13% plus or minus about 7% on either side. (Confidence interval). I do know that after 5 years we are considered to be in remission, so that sounds great to me!
When I was in treatment I read everything I could find on ER+ PR- HER2- which falls in the Luminal B category. Many of the journal articles do note that it has a higher risk of recurrence than more common Luminal A.
Now at almost 3 years to my anniversary (surgery date is what oncologists use) I’m grateful to be feeling good with everything clear so far. I’ve been getting Signatera (looks for circulating tumor cells that match my sample) screenings all along, and knowing they have all been negative is helpful to me. I also spend very little time thinking about BC compared to year one. I do still have all my saved articles though…
An article in BJS by M.G. Daley et al called “The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer” had some interesting graphs. Screenshot below. Markings are mine. (Search: BJS Open, 2021, zrab040 DOI: 10.1093/bjsopen/zrab040 for the full article.0 -
Shelle1, all is not grim! I'm coming on 8 yrs BC free. It helped me to become proactive in my health and well-informed. A bunch of us PR-negs have been through this and if you have questions or need moral support, please ask.
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8 years is Amazing. As someone new to this, who has been spinning and quite depressed, I often look at this thread for support. Thanks for sharing your story.
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