Anyone ER+ 1-10% weakly positive, PR- , HER2+?
Hello,
Anyone is ER+ 1-10% weakly positive, PR-, HER2+ ?
Do you take anti-hormone pills for ER+ 1-10% weakly positive ?
thank you
Applejj
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I am. I'm so weakly positive that I'm considered negative. No I didn't take hormonals. Two oncologists said it wasn't worth it given the side effects and that I'd probably see no benefit.
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Sorry - I'm negative/negative. Only HER2+ Someone else should be by soon.
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Hi LoriCA,
Thank you for your prompt response. I appreciate it.
Since you joined the BREASTCANCER.ORG in 2017, have you seen any other member's postings with similar situation as I do that ER weakly positive 1-10%? I only received two responses after I posted my concern in the .ORG.
thank you
Applejj
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I am ER-, and 10% PR+, HER2+
First biopsy was 7% PR+. At 7% oncologist and surgeon were adamant I needed no hormone treatment. 7% not considered positive
Surgery, Paclitaxel & Kanjinti, and radiation were proposed as treatment.
Post-surgery tumor analysis bumped PR status to 10% making it PR+. No one told me my diagnosis and treatment could change this dramatically post surgery, as the oncologists now recommended tamoxifen or Letrozole after I finished radiation. Although no one mentioned any of this to me for months
Doctors said hormone treatment could improve my odds by 1%. But I think that is based on ER+ research. I found little research on this profile (- + +). They said they wanted to offer this small possible improvement to me that was based on ER research. No one weighed the benefits against the risks (heart attack, stroke uterine cancer for hormone blockers, and osteoporosis and fracture for aromatase therapy).
I decided not to do hormone therapy.Has anyone had a similar situation? How did you resolve it?
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I am. 5% Er+, Pr-/Her2 3+. Completed TH, currently on Tamoxifen. Find it very heavy. ( ovar.cysts, high estadiol itc.) but my MO insists. 😁
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