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Topic: Ibrance (Palbociclib)

Forum: Stage IV/Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Feb 24, 2015 08:21PM - edited Dec 11, 2017 01:43PM by Moderators

Romansma wrote:

A bottle of Ibrance came in the mail today. I will start taking it tonight with Femara. Hoping that others starting on this drug will join me here to talk about side effects and how to avoid or treat them. So far, I've been warned about low white counts. I run very low as it is, probably because of my extensive bone mets. Anyone currently on Ibrance?

Edited by Mods to add Mod Note: Unfortunately, Romansma passed away in 2016. Our thoughts are with all who loved Hope.

Edited by Mods to add:

For more information on this medication, see the main Breastcancer.org site's section on Ibrance for information on how it works, who it's for, what to expect, and side effects. Also, read the latest research on the Research News on Ibrance pages.

Pfizer Oncology Together is a first-of-its-kind program for patients taking Pfizer Oncology medicines that offers dedicated social workers called 'Care Champions' to help navigate the complexities that accompany treatment, such as identifying resources to help find emotional support, and workplace transition, transportation and financial assistance.

For cancer patients taking a Pfizer Oncology medicine (e.g. Ibrance) or caregivers, please visit www.PfizerOncologyTogether.com.

For live support call: 1-877-744-5675

Hope Dx 10/22/2010, ILC, Right, 6cm+, Stage IIIB, Grade 2, 9/10 nodes, ER+/PR+, HER2- (FISH) Chemotherapy 11/1/2010 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Chemotherapy 4/1/2011 Abraxane (albumin-bound or nab-paclitaxel), Cytoxan (cyclophosphamide) Radiation Therapy 6/8/2011 Whole-breast: Breast, Lymph nodes, Chest wall Surgery 11/29/2011 Prophylactic ovary removal Dx 8/2013, ILC, Stage IV, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 9/17/2013 Faslodex (fulvestrant) Targeted Therapy 1/25/2014 Afinitor (everolimus) Radiation Therapy 2/11/2014 External: Bone Chemotherapy 12/6/2014 Xeloda (capecitabine) Hormonal Therapy 2/20/2015 Femara (letrozole) Targeted Therapy 2/20/2015 Ibrance (palbociclib)
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Apr 9, 2018 05:20PM - edited Apr 9, 2018 05:21PM by jaycee49

I have taken omeprazole on and off for years for gastritis. It's the only thing that works for me. One difference with me is that I take the 10 mg dose. The OTC Prilosec is 20 mg. My gastroenterologist prescribes the 10 mg dose for me. It sounds like your GP prescribes it (cheaper that way) but probably the 20 mg dose. Would he be willing to let you take 10 mg? If it works so well, why go off it? I took it for over a year straight and the doctor didn't complain. Maybe he should be paying more attention. But, hey, won't we be going to doctors at Walmart pretty soon?

Janet (dx with MS at 41, slows me down some) Dx 4/25/2014, IDC, 3cm, Stage IIB, Grade 2, 1/18 nodes, ER+/PR+, HER2+ Surgery 6/5/2014 Lymph node removal: Left, Sentinel, Underarm/Axillary; Mastectomy: Left Targeted Therapy 8/5/2014 Herceptin (trastuzumab) Chemotherapy 8/5/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 10/1/2014 Chest wall Hormonal Therapy 2/15/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/25/2016, IDC, Left, Stage IV, metastasized to bone/lungs, Grade 2, 1/18 nodes, ER+/PR+, HER2- (FISH) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Apr 9, 2018 05:31PM IntoLight wrote:

Thanks Jaycee. I know I can get it over the counter but I am trying not to. I will ask her. I know that going off the omeprazole means a sudden increase in acid, but I am miserable. I was doing so well!

Shining the light of God's grace to the world. Dx 5/20/2016, Left, 3cm, Stage IV, metastasized to bone/liver, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Apr 9, 2018 07:19PM dorimak wrote:

time-for-a-cureThank you for taking time to reply. I did hear that there are some on the IBRANCE study that are six years out. You were blessed that you were able to have that node removed. Fingers crossed and prayers for you too.

Dx 10/2001, IDC, Right, 2cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2- Dx 10/2005, IDC, Right, 2cm, Stage IIIB, Grade 2, ER+/PR+, HER2- Dx 1/2016, Stage IV, metastasized to other, Grade 2, ER+ Targeted Therapy 4/1/2016 Ibrance (palbociclib) Hormonal Therapy 4/1/2016 Femara (letrozole) Surgery Mastectomy: Right Radiation Therapy Chemotherapy AC Surgery Lumpectomy: Right
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Apr 9, 2018 07:25PM dorimak wrote:

IntoLight I have had bad reflux from IBRANCE that was getting worse and was on Pepcid. Had a endoscopy and findings were inflammation and gastroenterologist prescribed sucralfate. Haven't really get started on it. My MO had prescribed the Pepcid but gastro guy said it would't be effective but can't recall why. Hope you get relief. Blessings and prayers.

Dx 10/2001, IDC, Right, 2cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2- Dx 10/2005, IDC, Right, 2cm, Stage IIIB, Grade 2, ER+/PR+, HER2- Dx 1/2016, Stage IV, metastasized to other, Grade 2, ER+ Targeted Therapy 4/1/2016 Ibrance (palbociclib) Hormonal Therapy 4/1/2016 Femara (letrozole) Surgery Mastectomy: Right Radiation Therapy Chemotherapy AC Surgery Lumpectomy: Right
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Apr 9, 2018 07:57PM IntoLight wrote:

Dorimak, yeah, Pepcid doesn't work at all (which is what she prescribed). Sounds like what I am going through. Going to spend 3 days away with my DH. Then I will contact my MO and see what can be done. I can't live like this!

Shining the light of God's grace to the world. Dx 5/20/2016, Left, 3cm, Stage IV, metastasized to bone/liver, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Apr 9, 2018 08:45PM singlemom1 wrote:

Has anyone had a slight elevation of their alkaline phosphatase since being on Ibrance? Ihave been on Ibrance for 2.5 years and have been doing well. However, since December my alkaline phosphate has been slightly elevated for last couple of blood test. My MO said it could be from the Ibrance and she is not worried. It seems strange that after 2.5 years the Ibrance would now send it out of range. Has anyone else had this experience? Level was 110 in December and 114 in March.

Dx 2/7/2011, IDC, 2cm, Stage IIA, Grade 3, 0/5 nodes, ER+/PR+, HER2- Dx 9/2015, Stage IV, metastasized to lungs, ER+, HER2-
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Apr 9, 2018 11:28PM Stllivin wrote:

Hi, I don’t respond much but read a lot and have learned so much. I had very bad acid reflux and was put on Dexilant 60 mg daily. It’s the best. I don’t have to worry about reflux anymore. See if you can try it.

Suzy

Stllivin Dx 12/20/1997, IDC, Left, 2cm, metastasized to bone/lungs, 7/11 nodes, ER+/PR+, HER2-
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Apr 9, 2018 11:59PM - edited Apr 10, 2018 12:03AM by PatgMc

Intolight, I'm so sorry to hear of your problems. I took Prilosec when I started to have heartburn, etc while taking Letrozole in 2013. After reading online warnings about taking drugs like Prilosec long term, I decided to try something different. My friend went to a holistic doctor who recommended she try a gluten-free diet plus natural yogurt so I did the same with great results (also eventually quit the Letrozole). Since I've been on Arimidex, I developed a Hiatal Hernia with terrible heartburn...the whole shebang and need to go back to that diet. Tums helped for a long time and now I use Pepcid with good results but I've gone back to eating wheat and stopped the yogurt. Things are definitely better with 75mg Ibrance though! I will pray that you find something to make you more comfortable.

Pat G. Dx 2/1994, IDC, Left, 4cm, Stage IIB, Grade 3, 0/15 nodes, ER-/PR- Dx 3/2002, IDC, Right, <1cm, Stage IA, Grade 1, 0/3 nodes, ER+/PR+, HER2+ (FISH) Dx 3/2012, Right, 1cm, ER+/PR+, HER2- Dx 9/2016, IDC, 0/16 nodes, ER+/PR+, HER2- Targeted Therapy 10/1/2016 Ibrance (palbociclib) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap Chemotherapy FAC Chemotherapy Carboplatin (Paraplatin), Taxol (paclitaxel) Surgery Lymph node removal; Mastectomy; Reconstruction (right): Tissue expander placement
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Apr 10, 2018 12:57AM Leapfrog wrote:

IntoLight....I also have indigestion and gastritis from Ibrance and I take Lanzopram. I'm not sure whether this is the marketing name or generic name. Somac is also good and I'm not sure, once again, about the name. Just in case it helps you, I also follow a gluten free diet. From trial and error, I've discovered that my gastritis clears up on the GF diet but Ibrance definitely causes me to hiccup and have indigestion.

KattySmith....I'm sorry that Ibrance has passed its use by date for you. I hope you'll keep us up to date when you start your new dance, as PatGMcR calls it so eloquently.

Thanks lakewoman for your encouragement for my writing. I've now published fourteen blog posts, two of which are only housekeeping. It seems to be quite well received, having had 2,600 hits so far - a lot more than I expected. I've delved very deeply into quite personal details about my cancer story because I think, if I'm going to write about it to give an insider's view, I should do it properly. I've been able to keep it anonymous though.

Find your joy Dx 10/15/2016, ILC/IDC, Both breasts, 6cm+, Stage IV, metastasized to bone, Grade 3, 29/29 nodes, ER+/PR+, HER2- (IHC) Surgery 11/1/2016 Mastectomy: Left, Right Hormonal Therapy 12/10/2016 Femara (letrozole) Targeted Therapy 1/15/2017 Ibrance (palbociclib)
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Apr 10, 2018 12:59AM NettaGER wrote:

I am also having heartburn from the Ibrance that comes and goes depending on what I eat. But it appears that Pantoprazole has some long term effect on me, because if I take it for 1-2 days, I do not have the problems for about 1 week. So I do not take it continuously. I do not like to take it anyways, because I gives me the impression not to be able to digest food properly.

Additionally, please pay attention to the fact that Omeprazole/Pantoprazole does influence the resorption of Ibrance. It should not be taken at the same time but rather 12 hours apart.

Dx 8/31/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2- (FISH) Hormonal Therapy 9/15/2017 Femara (letrozole), Zoladex (goserelin) Targeted Therapy 9/15/2017 Ibrance (palbociclib)
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Apr 10, 2018 01:03AM time-for-a-cure wrote:

Into light - i have been on Omeprazole for several years due to a hiatal hernia and reflux. My PMD wanted me to get off of it, I tried several times without luck - I would just be miserable with heartburn etc. I now find that if I take 10 mg in the morning (half of an OTC dose) and then 20 mg famitodine at night, I do well. If I try to get rid of that 1/2 an Omeprazole, it jdoes not work. Just another idea. Hope you find what works for you.

Dx 12/2012, ILC, Right, 2cm, Stage IIB, metastasized to other, 0/2 nodes, ER+/PR-, HER2- Dx 1/2015, IDC, Stage IV, metastasized to other Surgery Lumpectomy: Right Targeted Therapy Hormonal Therapy Femara (letrozole) Targeted Therapy Ibrance (palbociclib)
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Apr 10, 2018 08:32AM SandiBeach57 wrote:

For those on Ibrance.. I just started cycle 18 Letrozole/Ibrance 100. Still doing okay (have to watch those low platelets thou). Don't know if it is the Ibrance or letrozole that is doing the job, but as long as something is working..I'm good!

2006 and 2007 DCIS ER+PR+, Oct 2016 Stage IV widespread liver mets, ER+PR-HER2-. Oct 2016 AC. Jan 2017 Letrozole/Ibrance
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Apr 10, 2018 10:34AM jensgotthis wrote:

Having a CT of chest, ab and pelvis today. Hoping to hear the the cancer has not invaded organs and that the blood clots in my lungs have resolved. It would be nice to get off the blood thinner if safe to to do so. There’s been a lingering pain where the liver is which seems to resolve diet. Bone scan is next week. I pray for lazy cancer cells who can’t figure out a way around this t

Dx 12/3/2015, IDC: Tubular, Left, 2cm, Stage IV, metastasized to bone, Grade 1, 0/12 nodes, ER+/PR+, HER2- Chemotherapy 1/5/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 5/2/2016 External: Bone Hormonal Therapy 5/24/2016 Surgery 5/25/2016 Lymph node removal: Left; Mastectomy: Left Targeted Therapy 9/14/2016 Ibrance (palbociclib) Hormonal Therapy 9/14/2016 Femara (letrozole) Radiation Therapy Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy
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Apr 10, 2018 11:13AM IntoLight wrote:

Wow, thank you all for answering me as I knew you would. You rock! You are never alone on this thread!

Shining the light of God's grace to the world. Dx 5/20/2016, Left, 3cm, Stage IV, metastasized to bone/liver, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Apr 10, 2018 12:21PM 50sgirl wrote:

Jensgotthis, Good luck with your scans today. Sometimes clots in the lungs take several months to resolve. Has your doctor given you an estimate of how long you will remain on the blood thinner? My DH hated them when he was on them, so I know how anxious you are to stop taking them. Do you know when you will get the results of the CT scans? Will you wait and get them after the bone scan? I hope the results are all good.

Hugs and prayers from, Lynne


Dx 6/5/2015, IDC, Left, 3cm, Stage IV, metastasized to bone, Grade 1, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/25/2015 Arimidex (anastrozole) Dx 8/9/2016, IDC, Left, 3cm, Stage IV, metastasized to bone/liver, Grade 1, ER+/PR+, HER2- Hormonal Therapy 8/10/2016 Faslodex (fulvestrant) Targeted Therapy 8/31/2016 Ibrance (palbociclib) Hormonal Therapy 7/3/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Chemotherapy 10/2/2018 Xeloda (capecitabine) Chemotherapy 2/11/2019 Taxol (paclitaxel)
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Apr 10, 2018 01:37PM amarantha wrote:

HI Jaycee ! Thanks for responding. Well, I do feel bad for my husband too, but its a huge struggle for him at his age too (luckily !! hahah) - I've tried a bunch of magic goops, I figure if I can get myself interested it would help both of us. Don't kill me but, pornography kind of works. :-D (in secret !!!)

current treatment - Halaven for IBC recurrence w mets -bone, skin, lymph nodes; past treatments - mastectomy x 2, neoadjuvant chemo-radiation w Cisplatin x2; Halaven, Afinitor, Ibrance, Faslodex, Tamoxifen, etc.
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Apr 10, 2018 05:17PM Piggy99 wrote:

Jen, good luck with your scans! Fingers crossed for lazy, stupid cancer and for resolved lung clots.

Diagnosed as Stage IV de novo at age 42. Dx 1/23/2018, ILC/IDC, Left, 6cm+, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2- Hormonal Therapy 1/31/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Targeted Therapy 2/7/2018 Ibrance (palbociclib) Hormonal Therapy 3/30/2018 Femara (letrozole)
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Apr 10, 2018 06:50PM lakewoman wrote:

Mica prayers for you and your onc tomorrow..Peaceful sleep tonite.

Sharlene
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Apr 10, 2018 08:55PM Jaylea wrote:

Jaycee, Amarantha, and all, I read an article that men whose wives can't accommodate sex actually miss the intimacy as much as the act. As low as my libido is, I try to cuddle, hug, and touch as much as possible, along with the manual alternates. But bottom line, this is me time now, so I'm done with any guilt over it.

Singlemom, haven't had any issues with alkaline phosphates, but take comfort that your MO isn't worried and keep an eye on it.

jensgotthis, sending you waves of comfort as you await your results.

Dx 10/2006, IDC, Left, Stage IIB, ER+, HER2- Dx 5/2017, IDC, Stage IV, metastasized to bone/lungs, ER+, HER2- Hormonal Therapy 6/19/2017 Femara (letrozole) Targeted Therapy 7/25/2017 Ibrance (palbociclib)
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Apr 11, 2018 01:27AM jensgotthis wrote:

Lynne, there was mention of 6 months as a deciding point for whether I’d stay on the blood thinner or not. After the first three months, there was improvement. We don’t know what’s causing them although it’s likely medicine related (I blame Lupron and of course cancer). I’ll be curious to see how this turns out.

I’m hoping for results on Wednesday but if they don’t post to MyChart then I’ll pop into the office Friday morning to request a print out. I’m not a very patient waiter when it comesto test results.

Bone scan is next Tuesday so I’ll make an appointment after that so we can discuss the meds.

Thanks for the good wishes. Man I’m glad I don’t have to drink that barium stuff for another three months.

Dx 12/3/2015, IDC: Tubular, Left, 2cm, Stage IV, metastasized to bone, Grade 1, 0/12 nodes, ER+/PR+, HER2- Chemotherapy 1/5/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 5/2/2016 External: Bone Hormonal Therapy 5/24/2016 Surgery 5/25/2016 Lymph node removal: Left; Mastectomy: Left Targeted Therapy 9/14/2016 Ibrance (palbociclib) Hormonal Therapy 9/14/2016 Femara (letrozole) Radiation Therapy Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy
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Apr 11, 2018 10:50AM GracieM2007 wrote:

Off to the dentist today, then dermatologist Friday to have a spot looked at on my face that is changing! If it’s not one thing, it’s another!!! Ugh!!

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Apr 11, 2018 11:34AM jaycee49 wrote:

Amarantha and Jaylea, thanks for the suggestions. With both, though (porn and cuddling, etc), I hate to get him "in the mood" and then not be able to follow through. He seems like he'd rather not get started at all and then be disappointed in the end. Maybe I'm wrong. I haven't asked recently. I guess I need to. Why is that so hard?

Good luck, Jen and Gracie.

Janet (dx with MS at 41, slows me down some) Dx 4/25/2014, IDC, 3cm, Stage IIB, Grade 2, 1/18 nodes, ER+/PR+, HER2+ Surgery 6/5/2014 Lymph node removal: Left, Sentinel, Underarm/Axillary; Mastectomy: Left Targeted Therapy 8/5/2014 Herceptin (trastuzumab) Chemotherapy 8/5/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 10/1/2014 Chest wall Hormonal Therapy 2/15/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/25/2016, IDC, Left, Stage IV, metastasized to bone/lungs, Grade 2, 1/18 nodes, ER+/PR+, HER2- (FISH) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Apr 11, 2018 12:13PM Tanya_Djamila wrote:

Good afternoon,

Medi port placement tomorrow. Thanks for the advice. I will be asleep.

Tanya

Dx 8/19/2003, ILC, Right, 6cm+, Stage IIIA, metastasized to bone/other, 28/28 nodes, ER+, HER2+ (IHC) Dx 4/19/2017, Stage IV, metastasized to bone/other, 0/0 nodes, ER+, HER2+ (IHC) Hormonal Therapy 6/20/2017 Faslodex (fulvestrant)
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Apr 11, 2018 12:51PM Tanya_Djamila wrote:

Tumor Marker experts

I recently had them done and don't understand the numbers. i googled it but would appreciate any assistance.

This is what I see on my chart.

*** Tumor Markers ** CEA 2039­6 2.2 ng/mL

CA27­29 17842­6 26.0 units/mL

Tanya

Dx 8/19/2003, ILC, Right, 6cm+, Stage IIIA, metastasized to bone/other, 28/28 nodes, ER+, HER2+ (IHC) Dx 4/19/2017, Stage IV, metastasized to bone/other, 0/0 nodes, ER+, HER2+ (IHC) Hormonal Therapy 6/20/2017 Faslodex (fulvestrant)
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Apr 11, 2018 01:05PM 50sgirl wrote:

Tanya, I think those TMs are great and are both within normal range. Do you know what they were in the past? I think that the 20396 and 178426 are simply codes and that your values are 2.2 for CEA and 26.0 for CA 27.29. WOOHOO! On the other hand, my CA 27.29 climbed to 400 this month. BOOOOO!

Hugs and prayers from, Lynne


Dx 6/5/2015, IDC, Left, 3cm, Stage IV, metastasized to bone, Grade 1, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/25/2015 Arimidex (anastrozole) Dx 8/9/2016, IDC, Left, 3cm, Stage IV, metastasized to bone/liver, Grade 1, ER+/PR+, HER2- Hormonal Therapy 8/10/2016 Faslodex (fulvestrant) Targeted Therapy 8/31/2016 Ibrance (palbociclib) Hormonal Therapy 7/3/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Chemotherapy 10/2/2018 Xeloda (capecitabine) Chemotherapy 2/11/2019 Taxol (paclitaxel)
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Apr 11, 2018 06:38PM Tanya_Djamila wrote:

14 years ago my onc told me not to worry about them they’re not reliable.

I still have a cancer lesion in my hip 3.3 cm so I expect to see something.

I hope the numbers mean nothing for you. I read something online about the numbers being influenced by hormones from meat we eat.

I pray yours mean absolutely nothing!

Thank you for the info

Tanya

Dx 8/19/2003, ILC, Right, 6cm+, Stage IIIA, metastasized to bone/other, 28/28 nodes, ER+, HER2+ (IHC) Dx 4/19/2017, Stage IV, metastasized to bone/other, 0/0 nodes, ER+, HER2+ (IHC) Hormonal Therapy 6/20/2017 Faslodex (fulvestrant)
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Apr 11, 2018 06:56PM Ciaci wrote:

This may be TMI, but I just wanted to say thank you, on behalf of my husband (though he'll never know Winking) - because of what some of you have said, we had a little "afternoon delight", for the first time in MONTHS. Uncomfortable at first, but then it was fine, and now he's walking around with a bounce in his step, and a grin on his face.

Seriously, I think it was easy to justify focusing on myself (who could blame me?), and also easy to forget that he's going through this, too. But I do want to emphasize that it wasn't painful for me, just uncomfortable. I think that makes a difference...

Dx 4/18/2017, IDC, Left, 1cm, Stage IV, metastasized to bone, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 4/23/2017 Lumpectomy: Left; Lymph node removal: Sentinel, Underarm/Axillary Hormonal Therapy 7/12/2017 Femara (letrozole) Targeted Therapy 7/31/2017 Ibrance (palbociclib)
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Apr 11, 2018 08:43PM lakewoman wrote:

I think TMI works at times!! Been on ibrance and letrozole a week..Been about 6 weeks since I was diagnosed Mets..A couple days after that we were very intimate and yes I responded. Then tests and more tests and biopsies and emotional adjustment. Today I wasn't responsive ..Was I dumb not to have my usual bottle of beer or glass of wine..Thought alcohol was out..BUT???? help????

Sharlene
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Apr 12, 2018 05:46PM janky wrote:

Hi everyone, just looking to vent! I just finished my 1 week off of my 2nd cycle of Ibrance and once again blood work is low, neutrophils are super low :( , so I have to have it repeated next Thursday, so distressing! My report says my red cell distribution width is high - sheesh, I wish I could balance this better ;) Just wanted to 'de-stress'...

Dx 11/7/2016, IDC, Left, 2cm, Stage IV, metastasized to bone, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 12/16/2016 Chemotherapy 2/9/2017 Radiation Therapy 5/16/2017
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Apr 12, 2018 05:57PM 50sgirl wrote:

Janky, It took many months for my blood counts to rebound quickly enough to start back on Ibrance after just one week off. I know how frustrating that can be. Don't dispair. What you are experiencing is very common. My RDW has always been high while on Ibrance. My MO is not concerned about it. I am 21 months into the Ibrance ride, and I have come to expect and accept the weird blood counts. I have never had any significant problems, and I feel great, so I am nice and calm. I hope your results are within acceptable limits next week.

Hugs and prayers from, Lynne


Dx 6/5/2015, IDC, Left, 3cm, Stage IV, metastasized to bone, Grade 1, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/25/2015 Arimidex (anastrozole) Dx 8/9/2016, IDC, Left, 3cm, Stage IV, metastasized to bone/liver, Grade 1, ER+/PR+, HER2- Hormonal Therapy 8/10/2016 Faslodex (fulvestrant) Targeted Therapy 8/31/2016 Ibrance (palbociclib) Hormonal Therapy 7/3/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Chemotherapy 10/2/2018 Xeloda (capecitabine) Chemotherapy 2/11/2019 Taxol (paclitaxel)

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