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Topic: Ibrance (Palbociclib)

Forum: Stage IV/Metastatic Breast Cancer ONLY —

Please respect that this forum is for members with stage IV/metastatic breast cancer only. There is a separate forum for caregivers and friends: Caring for Someone with Stage 4 or Mets.

Metastatic breast cancer (MBC; also called stage IV) is breast cancer that has spread to other parts of the body, most commonly the bones, liver, brain, or lungs. Metastatic breast cancer can be treated but not cured. Metastatic disease is NOT hopeless. There are a wide variety of treatment options for metastatic breast cancer, and new medicines are being tested every day. More and more people are living life to the fullest while being treated for metastatic breast cancer.

Note: Please contact your doctor for any specific concerns about symptoms you are experiencing or your course of treatment.

Learn more about living with MBC.

Intro medically reviewed by: Brian Wojciechowski, M.D.
Last review date: November 22, 2020

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Posted on: Feb 24, 2015 05:21PM - edited Dec 11, 2017 10:43AM by Moderators

Romansma wrote:

A bottle of Ibrance came in the mail today. I will start taking it tonight with Femara. Hoping that others starting on this drug will join me here to talk about side effects and how to avoid or treat them. So far, I've been warned about low white counts. I run very low as it is, probably because of my extensive bone mets. Anyone currently on Ibrance?

Edited by Mods to add Mod Note: Unfortunately, Romansma passed away in 2016. Our thoughts are with all who loved Hope.

Edited by Mods to add:

For more information on this medication, see the main Breastcancer.org site's section on Ibrance for information on how it works, who it's for, what to expect, and side effects. Also, read the latest research on the Research News on Ibrance pages.

Pfizer Oncology Together is a first-of-its-kind program for patients taking Pfizer Oncology medicines that offers dedicated social workers called 'Care Champions' to help navigate the complexities that accompany treatment, such as identifying resources to help find emotional support, and workplace transition, transportation and financial assistance.

For cancer patients taking a Pfizer Oncology medicine (e.g. Ibrance) or caregivers, please visit www.PfizerOncologyTogether.com.

For live support call: 1-877-744-5675

Hope Dx 10/22/2010, ILC, Right, 6cm+, Stage IIIB, Grade 2, 9/10 nodes, ER+/PR+, HER2- (FISH) Chemotherapy 11/1/2010 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Chemotherapy 4/1/2011 Abraxane (albumin-bound or nab-paclitaxel), Cytoxan (cyclophosphamide) Radiation Therapy 6/8/2011 Whole-breast: Breast, Lymph nodes, Chest wall Surgery 11/29/2011 Prophylactic ovary removal Dx 8/2013, ILC, Stage IV, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 9/17/2013 Faslodex (fulvestrant) Targeted Therapy 1/25/2014 Afinitor (everolimus) Radiation Therapy 2/11/2014 External: Bone Chemotherapy 12/6/2014 Xeloda (capecitabine) Hormonal Therapy 2/20/2015 Femara (letrozole) Targeted Therapy 2/20/2015 Ibrance (palbociclib)
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Nov 26, 2020 11:23AM SondraF wrote:

Happy Thanksgiving to all back in the US. Aprilgirl - you and I started about the same time- hard to believe its been a year already!

Ladies on Zoladex - question, is there any leeway on that injection? Looking at travel for next year and I just counted the days and its not opportune. Can you take it early instead? Ugh, I wish they would just rip out my ovaries already.

Dx 9/27/2019, IDC, Right, 5cm, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- Targeted Therapy 11/29/2019 Ibrance (palbociclib) Hormonal Therapy 11/29/2019 Femara (letrozole), Zoladex (goserelin)
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Nov 26, 2020 11:57AM Cure-ious wrote:

Happy Thanksgiving to All!!!

RK2020; OK, so where they say, for example
PFS appears to favor those pts who continued the CDK4/6i : rwPFS 11.27 months, 95%CI [8.87, 13.31]

this means that the "real-world" PFS was 11.37 months (half did better, half did worse), with a 95% confidence interval (95% of the patients went between 8.87-13.3 months)

Dx 10/2003, IDC, Stage IIB, ER+/PR+, HER2- Dx 7/2015, Stage IV, metastasized to bone, ER+/PR-, HER2-
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Nov 26, 2020 12:00PM candy-678 wrote:

Sondra- My experience with Lupron for me, Zoladex for others (insurance thing). I cannot get my shot early as my insurance won't allow. I was 10 days late once due to my previous MO wanted to get my blood tests and injections together for ease with scheduling. She was ok with me being 10 days late. Didn't really matter later because I had to hold my Ibrance and blood tests times were changed again. I don't know if the meds are the same as far as if you need them right on time.

Found mets on CT for unrelated issue. I only had 2 treatments with IV chemo for the Stage II, then found Stage 4 and switched to hormone therapy/targeted therapy. I consider myself de novo. Also using Xgeva injections for bone mets Dx 6/2017, ILC/IDC, Left, 3cm, Stage IIB, Grade 3, 0/1 nodes, ER+/PR+, HER2- Dx 9/2017, ILC/IDC, Stage IV, metastasized to bone/liver, 0/1 nodes, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole), Zoladex (goserelin) Chemotherapy AC Surgery Lymph node removal: Sentinel; Mastectomy: Left
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Nov 26, 2020 12:30PM Cure-ious wrote:

RK2020: For comparison, for the Ibrance-Letrozole trial:

The probability of progression‐free survival at 1 year was 75.6% (90% confidence interval, 62.4‐84.7). Median progression‐free survival was 35.7 months (95% confidence interval, 21.7‐46.7). Objective response rate and disease control rate were 47.6% (95% confidence interval, 32.0‐63.6) and 85.7% (95% confidence interval, 71.5‐94.6), respectively.

Bone-only averages were longer, de novo averages were longer, first line treatments averages were longer, etc. Objective response rate refers to shrinking of tumors where disease control rate refers to stable scans - so these are how the numbers look when you have a really outstanding result...


Dx 10/2003, IDC, Stage IIB, ER+/PR+, HER2- Dx 7/2015, Stage IV, metastasized to bone, ER+/PR-, HER2-
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Nov 26, 2020 01:37PM RhosgobelRabbit wrote:

Just checking in to wish my US sisters a happy Thanksgiving :) Just me and my beloved this year. Bbq glazed chicken breast, mac and cheese, stuffing, caesar salad and apple pie with vanilla bean ice cream. Enjoying a mild fall day here. Colorful leaves are all gone but getting one heck of a sunset tonight :) Thankful to have you ladies to go through this with and thankful you guys put up with me :)

PS: Yep, I'm still waiting. Oh well, at least I have warm pie with a dollop of cold ice cream and beautiful sunset to soothe me. I actually had one of those days today where I didnt feel like frazzled electrical cords. I'm having a lot more of them as time has gone on. I'm really trying to get better at it mostly by learning unravel the rats nest of emotions and just learn to "be". I'm working on that most of all right now. And believe it or not am weening off my need for sleep med assistance (I'm proud of myself for this especially).

Happy Thanksgiving to my US sisters and love to the rest of you :)

Mets @ Rads planning. Mets to Pelvis, Femurs, Shoulders, Ribs, T. Spine, L. Spine, Sternum, Sacrum/SI Joints. MyRisk neg. KEAP1 "Courage of the heart is very rare, there's a power when its there" 37yrs old @ IV DX. lifeandirises.home.blog/ Dx 7/30/2018, IDC, Right, 4cm, Stage IIB, Grade 2, ER+/PR+, HER2- Chemotherapy 9/27/2018 AC + T (Taxol) Hormonal Therapy 9/27/2018 Zoladex (goserelin) Dx 4/19/2019, IDC, Right, 3cm, Stage IIB, Grade 2, 5/16 nodes, ER+/PR+, HER2- (IHC) Surgery 4/19/2019 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Right Hormonal Therapy 5/14/2019 Zoladex (goserelin) Dx 5/17/2019, IDC, Right, Stage IV, metastasized to bone, ER+/PR+, HER2- (IHC) Surgery 10/2/2019 Prophylactic ovary removal Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Aromasin (exemestane)
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Nov 26, 2020 04:08PM RK2020 wrote:

Cure-ious...ah ha! I’ve read so many studies and had googled that CI was Confidence Interval but I still couldn’t make sense of it all. Your responses were very helpful. Thank you!

Dx 5/2016, IDC, Right, 1cm, Stage IIA, Grade 3, ER+/PR+, HER2- Dx 3/2020, IDC, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- Chemotherapy AC + T (Taxol) Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy External: Bone Radiation Therapy Whole-breast: Breast, Lymph nodes
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Nov 26, 2020 06:09PM BevJen wrote:

Funny of the day for those of you who are paying high co-pays on your Ibrance --

You know how many of us have complained about the packaging about Ibrance now? Well, beware, because sometimes it's not so hard to get those little suckers out of the cardboard holder. Tonight I was standing in the kitchen and pushed my pill out from the card. Lo and behold, the pill literally popped out (quite unusual these days) and skipped on the counter and went straight into the garbage disposal. I looked at the sink for a couple of seconds to try and decide if I should fish the pill out, considering how much each of those damn pills costs. But, I decided that I didn't know what was really, truly lurking in the garbage disposal, and that I should err on simply taking tomorrow's pill today. That will mean only 20 days this month. But not knowing what was in the garbage disposal after cooking Thanksgiving dinner -- nah, just didn't seem like the right move.

Moral of the story: sometimes the packaging isn't so difficult to get the pill out of! Beware!


Microwave Ablations of the Liver: 7/2019; 10/2020; 12/2020 Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/4/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Radiation Therapy Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Femara (letrozole)
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Nov 26, 2020 06:15PM JACK5IE wrote:

Happy Thanksgiving everyone!

Blessings On Thanksgiving... | Thanksgiving messages, Happy thanksgiving pictures, Happy thanksgiving day

Dx 7/2009, IDC, Left, Stage IIB, Grade 2, 4/11 nodes, ER+/PR+, HER2- Chemotherapy 7/31/2009 TAC Hormonal Therapy 12/31/2009 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/31/2010 Lumpectomy: Left Radiation Therapy 4/30/2010 Whole-breast: Breast, Lymph nodes Surgery 6/30/2010 Lymph node removal; Mastectomy: Left Hormonal Therapy 7/31/2015 Femara (letrozole) Dx 12/2017, Stage IV, metastasized to bone, ER+/PR-, HER2- (FISH) Radiation Therapy External: Bone Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant)
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Nov 26, 2020 06:24PM Snow-drop wrote:

Happy thanksgiving! I am thankful for all of you amazing ladies. It was (still is) unknown world that suddenly I entered to. My fears, sadness, disappointment and scanxiety are more manageable with your help and support. I learned a lot from you. I started ibrance December last year and joined bco thorough a search, looking for some answers to my questions, then saw a lot of good information are sharing here..

Sondra, you can go for higher dosage of zoladex it is good for 3 months.

I’ll see my new MO January 21, I’ll post here her advice here about the vaccine.

De Novo stage IV Dx 9/2019, IDC, Left, 4cm, Stage IV, metastasized to bone/other, Grade 2, ER+/PR+, HER2- (IHC) Hormonal Therapy Zoladex (goserelin) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone Targeted Therapy Ibrance (palbociclib)
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Nov 26, 2020 08:21PM - edited Nov 26, 2020 08:23PM by Tinkerbell107

BevJen: thanks for the chuckle. I could easily see me doing something like this with the Ibrance cardboard holder. Tomorrow I will be extra careful. Lol.

Happy thanksgiving everyone.

Dx 8/23/2019, IDC, Left, 2cm, Stage IV, metastasized to bone, Grade 3, 5/6 nodes, ER+/PR+, HER2-
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Nov 26, 2020 08:28PM Tina2 wrote:

BevJen,

Funny! I laughed out loud when I got to "...straight into the garbage disposal."

Tina





Stage I, mastectomy, 1985.Stage I, mastectomy, 1995. Stage IV, lung mets treated with Faslodex 2011-/2018. Treatment hiatus 9/2018-3/2020. Ibrance and Faslodex 3/2020. Faslodex only 11/20. Dx Stage IV, mets, ER+/PR+
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Nov 26, 2020 08:46PM SerenitySTAT wrote:

BevJen - Yipes! You made the right choice. I am finishing my first set of tablets, and there's no cardboard. ???


"Do not overlook the little joys!" (Hesse, 1905) 🐶☕️🛀🖼🥐🌲🎭 Dx 11/2015 IDC Left IIIC 10/11 nodes ER+PR+HER2-, 12/2015 Left Mast, 2/2016 4 AC+12 Taxol, 9/2016 Rads Nodes Chest wall 15+4 boosts, 10/2016 Tamox, 4/2019 Exemestane, 12/2019 Ibrance/Xgeva
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Nov 27, 2020 12:02AM SondraF wrote:

The cost of those pills it's like losing your engagement ring down the disposal!

Dx 9/27/2019, IDC, Right, 5cm, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- Targeted Therapy 11/29/2019 Ibrance (palbociclib) Hormonal Therapy 11/29/2019 Femara (letrozole), Zoladex (goserelin)
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Nov 27, 2020 02:41AM KBL wrote:

Omg, BevJen, funny and sad at the same time. Anywhere else but the garbage disposal. Ugh

Dx 5/1/2019, ILC, Stage IV, metastasized to bone/other, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/23/2019 Femara (letrozole) Targeted Therapy 6/23/2019 Ibrance (palbociclib)
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Nov 27, 2020 03:03AM Karenfizedbo15 wrote:

Grateful thanks as always to you Curious for your diligence in researching! Just to say that no matter how effective CDK4/6 inhibitors as second line treatment seem to be...and that’s great news...if they are not approved by the authorities to be used as second line then we have no access to them. Currently in the UK they are only approved as first line in the metastatic setting. My team think it’s coming as evidence builds, but we are behind the curve sadly for folk in my position 😥

Surgery 9/6/2007 Lymph node removal: Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2-
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Nov 27, 2020 04:34AM BevJen wrote:

SerenitySTAT,

Wow, your packaging looks like the original packaging -- I think most of us in the US now get the pills in a full cardboard box, with separate three-part cardboard "folders" for each week. In those packages, the tablet is underneath both cardboard and foil. That's what people had been complaining about a few months ago.

Nevertheless, guard those pills or you could have the same fate as me. And, as Sondra said, it's like losing jewelry down the drain at this price!

Microwave Ablations of the Liver: 7/2019; 10/2020; 12/2020 Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/4/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Radiation Therapy Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Femara (letrozole)
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Nov 27, 2020 07:56AM dutchiris wrote:

I have widespread mets to bone and some lymph nodes in my chest. All was stable on scans on 11/25 except mild progression in L2 and left sacrum. L2 met went from .8cm to 1.3cm. I do have some increased pain these areas. We are staying with I/L for now. Anyone had a similar experience and not had further progression on next scans?

Dx 1/25/2013, IDC, Left, Stage IIIC, Grade 2, 19/24 nodes, ER+/PR+, HER2- Chemotherapy 2/21/2013 AC + T (Taxol) Surgery 6/18/2013 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Hormonal Therapy 7/1/2013 Radiation Therapy 7/14/2013 Dx 7/26/2019, IDC, Stage IV, metastasized to bone, ER+/PR-, HER2- (IHC) Hormonal Therapy 8/9/2019 Femara (letrozole) Targeted Therapy 8/16/2019 Ibrance (palbociclib)
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Nov 27, 2020 08:45AM BlueGirlRedState wrote:

BevJen - thanks for the warning on the package. I will stay well away from the disposal and the dog when punching out a pill. If you ever do need to fish anything out, be sure to unplug it first. I wonder if home owner insurance would reimburse........

Does anyone know if we really do need to keep it in original package? I know the instrucdtions tell us to. I have a river trip planned for April, and wonder if I could just store them in a recycled pill bottle. Are they more fragile than capsules and need to stay unexposed as much as possible?

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Nov 27, 2020 02:57PM RhosgobelRabbit wrote:

I got a very big gift in my mailbox today, my report. I clutched my thick envelope for a couple of minutes and just said "Stable Stable Stable" over and over again. While I was reading it I think my eyes got crosseyed or something multiple times because my eyes were trying to read so fast. Totally new person did my report this time, usually it was 2 different guys who seem to do my reports but this was a woman.

I guess I'm leading this all up to say in a very "Just get to the point and spit out lady" kinda way........ STABLE MABLE :) Lung irritation/nodule still there and unchanged. Liver a little irritated but no lesions. Lymph nodes look ok in chest. Spleen still has calcifications from damage from early stage treatment chemo ( I remember them from my initial IV diagnosis), I also found out I have an accessory spleen, lol, Anyone find anything kinda unique and strange like that? My beloved calls me his riblet, you know Eve came from the rib of Adam. That I'm apart of him and awwwwwwwww. Well, I finally had a retort back of my own, so I call him my little accessory spleen, because apparently the rib wasn't enough.

BevJen, I love the pause and thinking about fishing it out. I dropped a capsule back when I was on them on the car carpet floor once and it landed right on where my muddy foot had been, which was muddy from moonwalking in the front lawn from stepping in dog turd in the attempt to deturd. No way to buff the outside of the capule or run it under water to cleanse. It was one of those moments I had to sigh and say, 20 days it is. Thee pills are precious, something like 1,000 a pop when you think of it, and even all the more precious with high out of pocket cost or co-pay.

Anywho, that's my report and am sticking to it. Now I'm going to do a very bad job at not thinking about it for another 3 months, but hey, A for effort. :)

Mets @ Rads planning. Mets to Pelvis, Femurs, Shoulders, Ribs, T. Spine, L. Spine, Sternum, Sacrum/SI Joints. MyRisk neg. KEAP1 "Courage of the heart is very rare, there's a power when its there" 37yrs old @ IV DX. lifeandirises.home.blog/ Dx 7/30/2018, IDC, Right, 4cm, Stage IIB, Grade 2, ER+/PR+, HER2- Chemotherapy 9/27/2018 AC + T (Taxol) Hormonal Therapy 9/27/2018 Zoladex (goserelin) Dx 4/19/2019, IDC, Right, 3cm, Stage IIB, Grade 2, 5/16 nodes, ER+/PR+, HER2- (IHC) Surgery 4/19/2019 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Right Hormonal Therapy 5/14/2019 Zoladex (goserelin) Dx 5/17/2019, IDC, Right, Stage IV, metastasized to bone, ER+/PR+, HER2- (IHC) Surgery 10/2/2019 Prophylactic ovary removal Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Aromasin (exemestane)
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Nov 27, 2020 03:07PM BevJen wrote:

Rabbit,

Such wonderful news for you! How wonderful. So glad that you got the report before seeing your MO.

Yay, yay, yay, yay, yay!

Microwave Ablations of the Liver: 7/2019; 10/2020; 12/2020 Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/4/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Radiation Therapy Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Femara (letrozole)
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Nov 27, 2020 03:44PM Karenfizedbo15 wrote:

‘A’ for effort indeed Rabbit. Whew for you and yes to making a poor effort ( or finding a distraction) for another 3 months in our scanxiety club. 👏🏻👏🏻👏🏻

Surgery 9/6/2007 Lymph node removal: Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2-
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Nov 27, 2020 04:27PM Tanya_Djamila wrote:

Rabbit congratulations for STABLE!!!!

Tany

Tanya Dx 8/19/2003, ILC, Right, 6cm+, Stage IIIA, metastasized to bone/other, 28/28 nodes, ER+, HER2+ (IHC) Dx 4/19/2017, Stage IV, metastasized to bone/other, 0/0 nodes, ER+, HER2+ (IHC) Hormonal Therapy 6/20/2017 Faslodex (fulvestrant)
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Nov 27, 2020 04:58PM KBL wrote:

Rabbit, so happy for you.

Dx 5/1/2019, ILC, Stage IV, metastasized to bone/other, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/23/2019 Femara (letrozole) Targeted Therapy 6/23/2019 Ibrance (palbociclib)
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Nov 27, 2020 05:21PM Rosie24 wrote:

Great news Rabbit

Dx 1/23/2019, DCIS/IDC, Left, 3cm, Stage IV, metastasized to liver, Grade 2, ER+/PR-, HER2- (FISH) Hormonal Therapy 1/24/2019 Femara (letrozole) Targeted Therapy 1/24/2019 Ibrance (palbociclib) Surgery 12/3/2019 Lumpectomy: Left Surgery 12/3/2019 Lymph node removal: Sentinel Radiation Therapy Whole-breast
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Nov 27, 2020 06:23PM candy-678 wrote:

RRabbit- Woohoo !!!!!!!!!!! Stable Mable!!!!!!!!!!!! Good for you.

Found mets on CT for unrelated issue. I only had 2 treatments with IV chemo for the Stage II, then found Stage 4 and switched to hormone therapy/targeted therapy. I consider myself de novo. Also using Xgeva injections for bone mets Dx 6/2017, ILC/IDC, Left, 3cm, Stage IIB, Grade 3, 0/1 nodes, ER+/PR+, HER2- Dx 9/2017, ILC/IDC, Stage IV, metastasized to bone/liver, 0/1 nodes, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole), Zoladex (goserelin) Chemotherapy AC Surgery Lymph node removal: Sentinel; Mastectomy: Left
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Nov 27, 2020 06:47PM JACK5IE wrote:

Miss Rabbit...I'm so happy for you!!! 😊

Dx 7/2009, IDC, Left, Stage IIB, Grade 2, 4/11 nodes, ER+/PR+, HER2- Chemotherapy 7/31/2009 TAC Hormonal Therapy 12/31/2009 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/31/2010 Lumpectomy: Left Radiation Therapy 4/30/2010 Whole-breast: Breast, Lymph nodes Surgery 6/30/2010 Lymph node removal; Mastectomy: Left Hormonal Therapy 7/31/2015 Femara (letrozole) Dx 12/2017, Stage IV, metastasized to bone, ER+/PR-, HER2- (FISH) Radiation Therapy External: Bone Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant)
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Nov 28, 2020 12:07AM SondraF wrote:

Aw Rabbit - thats wonderful to hear!

Both the letrozole and Ibrance come in boxes here, with the pills set in foil-backed strips. Easy to store and transport, although I will say Ive had my share of capsules go skittering off my desk and on to the floor where I need to rescue them before the cats get it.

Dx 9/27/2019, IDC, Right, 5cm, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- Targeted Therapy 11/29/2019 Ibrance (palbociclib) Hormonal Therapy 11/29/2019 Femara (letrozole), Zoladex (goserelin)
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Nov 28, 2020 05:49AM thereishope4us wrote:

awesome news of you stable report, Rabbit!

Haven’t been checking these days but hoping everyone is doing well. My MO switched me from 100 mg to 75 mg Ibrance 2 months ago due to low neutrophil count. Unfortunately, I just checked the report, my count is still low at 0.8 after a week break. Not horrible but probably need another week off to start. It’s been almost 3 years for me on the I/F combo. I hope it’s still working, scan should be done this month but I am too afraid to do so before the holidays. Maybe just need to build up the courage and get some result for a peace of mind and decide on future course of treatment directly.

Life is otherwise good!!!

Have a great weekend all and stay safe.

there is hope 4 us

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Nov 28, 2020 06:24AM Tina2 wrote:

Yay, Rabbit! Another reason to give thanks!

Tina

Stage I, mastectomy, 1985.Stage I, mastectomy, 1995. Stage IV, lung mets treated with Faslodex 2011-/2018. Treatment hiatus 9/2018-3/2020. Ibrance and Faslodex 3/2020. Faslodex only 11/20. Dx Stage IV, mets, ER+/PR+
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Nov 28, 2020 09:28AM Snow-drop wrote:

Rabbit good news I’m happy for you, now enjoy your stress-less-weekend 🤗

There is hope 4 us, I’m sorry about your ANC, which happens for all of us, my new MO’s nurse said they recommend ibrance 7/7 ie one week on/ one week off, to allow blood rebound. Also some of ladies in this thread use 5/2 schedule.

It’s me that thinks why pharmaceuticals have not yet invented (?) effective drugs without harmful side effects for mbc, in comparison with covid vaccine???? Do they need deadlines or what?

De Novo stage IV Dx 9/2019, IDC, Left, 4cm, Stage IV, metastasized to bone/other, Grade 2, ER+/PR+, HER2- (IHC) Hormonal Therapy Zoladex (goserelin) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone Targeted Therapy Ibrance (palbociclib)

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