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Topic: Abraxane

Forum: Stage IV/Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Feb 2, 2016 11:20PM

DancingVeggie wrote:

Weird that there hasn't been a thread devoted to Abraxane before this... here goes nothing!

Dx 10/6/2008, IDC, 4cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Chemotherapy 12/17/2008 AC Chemotherapy 2/4/2009 Taxol (paclitaxel) Radiation Therapy 4/16/2009 Breast Hormonal Therapy 5/31/2009 Dx 10/24/2012, 6cm+, Stage IV, mets, ER+/PR-, HER2- Targeted Therapy 11/5/2012 Avastin (bevacizumab) Chemotherapy 11/5/2012 Taxol (paclitaxel) Chemotherapy 9/23/2013 Xeloda (capecitabine) Hormonal Therapy 3/10/2014 Arimidex (anastrozole) Chemotherapy 6/25/2014 Halaven (eribulin) Chemotherapy 8/18/2014 Carboplatin (Paraplatin), Gemzar (gemcitabine)
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Sep 23, 2018 11:18AM Wanderingneedle wrote:

I’m only on my second dose of the first cycle so don’t know yet how bad things will get but I took a Zofran yesterday to try to prevent nausea. I took a Rolaids too since they don’t interfere. Zofran works on seratonin so it tells your brain you’re not sick where an antacid tells your belly it’s not sick. I don’t think the Zofran has an immediate effect so you have to plan ahead. It’s hard to determine at first when to take it since it’s for prevention. I don’t like taking a bunch of pills either but I talk myself into it. Some days it’s just routine and other days it’s a struggle. Maybe try it for a day or two and see if it helps.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Sep 26, 2018 07:02PM Wanderingneedle wrote:

Isthere a standard length of treatment for Abraxane or do they just figure it out as they go along? I asked the nurse today how long I will be on this and she didn’t know.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Sep 27, 2018 01:49AM GracieM2007 wrote:

My onc said six months and then for as long as it’s working and I can tolerate it

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Sep 27, 2018 10:32AM illimae wrote:

Wandering, Abraxane was my first line chemo (adverse reactions to the others) and I did 5 months, however it was weekly for me. I think it works out to be the same as 6 treatments given every 3 weeks.

Diagnosed at 41 Stage IV De Novo Dx 11/16/2016, IDC, Left, 5cm, Stage IV, metastasized to bone, Grade 3, 3/13 nodes, ER+/PR-, HER2+ (IHC) Chemotherapy 1/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Targeted Therapy 1/2/2017 Herceptin (trastuzumab) Targeted Therapy 1/2/2017 Perjeta (pertuzumab) Surgery 6/26/2017 Lumpectomy: Left; Lymph node removal: Underarm/Axillary Radiation Therapy 8/10/2017 Breast, Lymph nodes Dx 10/5/2017, IDC, Left, Stage IV, metastasized to brain Radiation Therapy 10/20/2017 External: Brain Radiation Therapy 4/18/2018 External: Brain Radiation Therapy 5/23/2019 External: Brain Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Sep 27, 2018 02:50PM Wanderingneedle wrote:

Thank you GracieM2007 and Illimae. It was a sudden change of plan and not a lot of information given. I see my MO next week and will ask questions. I have a trip planned in the coming weeks and planning ahead for holidays and what I may or may not be able to do. I was not on any treatment last year during the holidays so this will be new. I’m a planner and I’m finding it frustrating to not be able to plan. I guess I need multiple plans

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Oct 7, 2018 07:18PM Scwilly wrote:

I'm meant to be on a 3 weeks on, one week off regime for Abraxane. I had my first dose on 20th Sept, then my second on 28th after getting a shot to boost my neutrophils. After my second dose my neutrophil levels went down to 0.6, and with my platelets low and also low hemoglobin (8.4) I took a week of Abraxane. I'm hoping to have my third dose next week if my blood levels raise up. Ive been so tired, most likely due to my low red cell count. I really want this to work (who wants treatment to fail!) but it feels hard. I didn't get such a strong reaction when I was on Taxol.

I hoping things might settle down, but feel its not likely. I had to cancel a trip to the UK to see family/friends so feeling quite down about the whole processes.

How is everyone else getting on? Did anyone else treatment startup hard but settle down and become manageable?

Sarah


Dx 11/4/2013, IBC, Left, 2cm, Stage IIIB, Grade 2, 0/3 nodes, ER-/PR-, HER2- Chemotherapy 11/14/2013 AC Chemotherapy 1/14/2014 Taxol (paclitaxel) Surgery 4/29/2014 Radiation Therapy 6/24/2014 Whole-breast: Breast, Lymph nodes, Chest wall Dx 2/16/2015, DCIS, Right, 2cm, Stage 0, Grade 2, 0/6 nodes, ER+/PR-, HER2- Surgery 4/6/2015 Lymph node removal: Sentinel; Mastectomy: Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Surgery 3/23/2016 Reconstruction (left): Fat grafting; Reconstruction (right): Fat grafting Dx 11/15/2016, Stage IV, metastasized to liver, ER+ Hormonal Therapy 11/15/2016 Arimidex (anastrozole) Targeted Therapy 2/17/2017 Ibrance (palbociclib) Chemotherapy 8/31/2017 Xeloda (capecitabine) Dx 4/5/2018, Stage IV, metastasized to bone, ER+ Surgery 4/5/2018 Radiation Therapy 4/18/2018 Chemotherapy 5/3/2018 Other Chemotherapy 7/27/2018 Carboplatin (Paraplatin) Chemotherapy 9/20/2018 Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Aromasin (exemestane)
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Oct 7, 2018 07:32PM - edited Oct 7, 2018 07:32PM by GracieM2007

Sarah, I'm on week one if round four. They gave me iv iron last week and will again this week because my rbc are very low as well as hemoglobin. I haven't had to have anything for my wbc yet, thank goodness! Abraxane has been pretty tough on me, lots of neuropathy already and nausea, muscle soreness and absolutely no energy. They did lower my dose by 10% last month due to the neuropathy. Here's the good news...my tumor markers, which have done nothing but go up for two years, are almost within normal limits! It's not an easy chemo but it seems to be workjng

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Oct 7, 2018 08:09PM Scwilly wrote:

Gracie - so great to hear Abraxane is bringing your tumor markers down. :D

I'm happy to have had this extra week off but fear it will become the norm and I don't want to keep missing chemo. Maybe a lower dose would be the way for me. I am early days on this TX - maybe the iron IV would be something I should/could do. I'm having blood tests done on Tuesday - so I have a day or two if some form of boost is needed before chemo Friday.

Dx 11/4/2013, IBC, Left, 2cm, Stage IIIB, Grade 2, 0/3 nodes, ER-/PR-, HER2- Chemotherapy 11/14/2013 AC Chemotherapy 1/14/2014 Taxol (paclitaxel) Surgery 4/29/2014 Radiation Therapy 6/24/2014 Whole-breast: Breast, Lymph nodes, Chest wall Dx 2/16/2015, DCIS, Right, 2cm, Stage 0, Grade 2, 0/6 nodes, ER+/PR-, HER2- Surgery 4/6/2015 Lymph node removal: Sentinel; Mastectomy: Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Surgery 3/23/2016 Reconstruction (left): Fat grafting; Reconstruction (right): Fat grafting Dx 11/15/2016, Stage IV, metastasized to liver, ER+ Hormonal Therapy 11/15/2016 Arimidex (anastrozole) Targeted Therapy 2/17/2017 Ibrance (palbociclib) Chemotherapy 8/31/2017 Xeloda (capecitabine) Dx 4/5/2018, Stage IV, metastasized to bone, ER+ Surgery 4/5/2018 Radiation Therapy 4/18/2018 Chemotherapy 5/3/2018 Other Chemotherapy 7/27/2018 Carboplatin (Paraplatin) Chemotherapy 9/20/2018 Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Aromasin (exemestane)
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Oct 7, 2018 08:17PM GracieM2007 wrote:

With the iron, they can do a blood test to see if you are low on iron, that helps to get the insurance to pay for it. And my onc said lowering the dose doesn’t have any effect on how well it works, so you could at least ask about those.

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Oct 7, 2018 08:35PM Scwilly wrote:

Thanks for the advise - I will be ready when I get my bloods done on Tuesday.

Dx 11/4/2013, IBC, Left, 2cm, Stage IIIB, Grade 2, 0/3 nodes, ER-/PR-, HER2- Chemotherapy 11/14/2013 AC Chemotherapy 1/14/2014 Taxol (paclitaxel) Surgery 4/29/2014 Radiation Therapy 6/24/2014 Whole-breast: Breast, Lymph nodes, Chest wall Dx 2/16/2015, DCIS, Right, 2cm, Stage 0, Grade 2, 0/6 nodes, ER+/PR-, HER2- Surgery 4/6/2015 Lymph node removal: Sentinel; Mastectomy: Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Surgery 3/23/2016 Reconstruction (left): Fat grafting; Reconstruction (right): Fat grafting Dx 11/15/2016, Stage IV, metastasized to liver, ER+ Hormonal Therapy 11/15/2016 Arimidex (anastrozole) Targeted Therapy 2/17/2017 Ibrance (palbociclib) Chemotherapy 8/31/2017 Xeloda (capecitabine) Dx 4/5/2018, Stage IV, metastasized to bone, ER+ Surgery 4/5/2018 Radiation Therapy 4/18/2018 Chemotherapy 5/3/2018 Other Chemotherapy 7/27/2018 Carboplatin (Paraplatin) Chemotherapy 9/20/2018 Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Aromasin (exemestane)
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Oct 8, 2018 07:02PM Wanderingneedle wrote:

Always ask questions about your bloodwork if you have them. I don’t want to know just what it means, I want to know how it affects me regarding treatment and what’s “normal” with treatment. If you’re asking about things he hasn’t recommended let him explain why you don’t need it. Sometimes their decisions seem quite random until they explain it.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Oct 8, 2018 07:05PM Wanderingneedle wrote:

Finished the third week of my first round and my hair is falling out in chunks. Going to get a wig tomorrow. Doing this week and taking a trip for a week.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Oct 8, 2018 07:44PM Scwilly wrote:

WanderingNeedle - Mine is falling out too - expected but Im not happy. Oh well. Hope you get a great wig, I'm going shopping for a wig too as I want a shorter one than last time. Enjoy your trip

Dx 11/4/2013, IBC, Left, 2cm, Stage IIIB, Grade 2, 0/3 nodes, ER-/PR-, HER2- Chemotherapy 11/14/2013 AC Chemotherapy 1/14/2014 Taxol (paclitaxel) Surgery 4/29/2014 Radiation Therapy 6/24/2014 Whole-breast: Breast, Lymph nodes, Chest wall Dx 2/16/2015, DCIS, Right, 2cm, Stage 0, Grade 2, 0/6 nodes, ER+/PR-, HER2- Surgery 4/6/2015 Lymph node removal: Sentinel; Mastectomy: Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Surgery 3/23/2016 Reconstruction (left): Fat grafting; Reconstruction (right): Fat grafting Dx 11/15/2016, Stage IV, metastasized to liver, ER+ Hormonal Therapy 11/15/2016 Arimidex (anastrozole) Targeted Therapy 2/17/2017 Ibrance (palbociclib) Chemotherapy 8/31/2017 Xeloda (capecitabine) Dx 4/5/2018, Stage IV, metastasized to bone, ER+ Surgery 4/5/2018 Radiation Therapy 4/18/2018 Chemotherapy 5/3/2018 Other Chemotherapy 7/27/2018 Carboplatin (Paraplatin) Chemotherapy 9/20/2018 Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Aromasin (exemestane)
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Oct 9, 2018 12:40AM - edited Oct 9, 2018 11:50PM by skitzblitz

abraxane is kicking my butt. I had a week off the first round and theyndid lower the dose as well. My red platelets have been low and the past two times at the dr they told me I could get a transfusion if iwant one. Well I'm ready! I did my theee rounds and week off and I'm still tired and not rebounding.

I have my first scan Wednesday

I have not had the neuropathy so lucky there but I ache and ache so bad I just can't take it. I am hoping some is from low platelets as well.

I will ask about the iron iv but not sure if we have them here.

I really don't want the shots for the wbc, heard they were horrible.


Will keep you posted,

Sarah

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Oct 22, 2018 12:42PM mlc96 wrote:

Does anyone have itching and rash from Abraxane? I had 5 rounds of Taxol and had terrible rash and itching, was switched to Abraxane last week but rash and itching are the same. I was told to take Claritin daily, Bernedryl at night, was also given 1 week of Prednisone which has not helped at all. I'm supposed to have 6 more weeks of Abraxane, not sure how I will tolerate it unless I take Benedryl around the clock!

Dx 4/26/2012, IDC, Right, 6cm+, Stage IIIC, metastasized to bone, Grade 3, 0/8 nodes, ER+/PR+, HER2+ Targeted Therapy 7/10/2012 Herceptin (trastuzumab) Surgery 11/1/2012 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Radiation Therapy 1/26/2013 Whole-breast: Chest wall Hormonal Therapy 4/30/2016 Femara (letrozole) Dx 12/22/2016, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, 1/8 nodes, ER+/PR+, HER2+ Targeted Therapy 1/4/2017 Herceptin (trastuzumab) Chemotherapy 1/6/2017 Taxol (paclitaxel) Chemotherapy 11/19/2018 Navelbine (vinorelbine)
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Oct 22, 2018 01:33PM Wanderingneedle wrote:

mic96, have you had a long break between taxol and abraxane? Rash is listed as a common side effect. Have they offered you anything topical for relief rather than internal? Maybe a cortisone cream or an oatmeal bath may help? Good luck, I’m sure it’s extremely uncomfortable.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Oct 23, 2018 04:27PM mlc96 wrote:

There was no break between the Taxol and Abraxane, I'm getting weekly infusions for 12 weeks, the first 4 were Taxol and the rash started after the 2nd infusion. I have a cortisone cream to use topically. I did try an oatmeal bath last night and it helped a lot.

Dx 4/26/2012, IDC, Right, 6cm+, Stage IIIC, metastasized to bone, Grade 3, 0/8 nodes, ER+/PR+, HER2+ Targeted Therapy 7/10/2012 Herceptin (trastuzumab) Surgery 11/1/2012 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Radiation Therapy 1/26/2013 Whole-breast: Chest wall Hormonal Therapy 4/30/2016 Femara (letrozole) Dx 12/22/2016, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, 1/8 nodes, ER+/PR+, HER2+ Targeted Therapy 1/4/2017 Herceptin (trastuzumab) Chemotherapy 1/6/2017 Taxol (paclitaxel) Chemotherapy 11/19/2018 Navelbine (vinorelbine)
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Oct 26, 2018 05:17PM Wanderingneedle wrote:

mlc96, I found this while looking up blood pressure information. http://www.oncohealth.eu/en/patient-area/understanding-cancer/patient-information-support/general-information/treatment/chemotherapy/listado-farmacos/abraxane

It lists a rash as an allergic reaction, not a side effect. Aveeno lotion has oatmeal in and is very hydrating. It may offer a little topical relief. I hope you’re not on this for very long and can trade these side effects for something more tolerable.

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Oct 31, 2018 04:44PM mlc96 wrote:

Thank you for the info! I have (hopefully) 6 more weeks. I'm managing but can't wait for this to be over. I'm on Prednisone 10 mg daily, Claritin, benedryl, hryocortisone lotion and oatmeal baths before bed. If I have to have chemo again in the future, I will have to move to another drug, not Taxol or Abraxane.

Dx 4/26/2012, IDC, Right, 6cm+, Stage IIIC, metastasized to bone, Grade 3, 0/8 nodes, ER+/PR+, HER2+ Targeted Therapy 7/10/2012 Herceptin (trastuzumab) Surgery 11/1/2012 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Radiation Therapy 1/26/2013 Whole-breast: Chest wall Hormonal Therapy 4/30/2016 Femara (letrozole) Dx 12/22/2016, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, 1/8 nodes, ER+/PR+, HER2+ Targeted Therapy 1/4/2017 Herceptin (trastuzumab) Chemotherapy 1/6/2017 Taxol (paclitaxel) Chemotherapy 11/19/2018 Navelbine (vinorelbine)
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Nov 24, 2018 04:15PM klmpk wrote:

Hi All,

I've just started Abraxane with Carboplatin. 3 weeks on and 1 week off. I have my 2nd infusion on Monday. Feel really tired, but everything else is pretty random. An ache here a pain there. Came off of Xeloda (which I loved, no SEs to speak of). but it wasn't working. My first round of bc was ILC 50-75 % ER, PR +. Now i'm 1-10% ER, PR negative. that's almost triple negative which is really scary. Any advice any of you can shoot my way will be appreciated.

Karen

Dx 8/31/2013, ILC, Left, 3cm, Stage IIA, Grade 1, 0/1 nodes, ER+/PR-, HER2- Chemotherapy 9/27/2013 AC + T (Taxol) Surgery 3/27/2014 Lumpectomy: Left Radiation Therapy 4/29/2014 Multi-catheter: Breast Dx 11/6/2017, ILC, Stage IV, metastasized to other, 0/1 nodes, ER+/PR+, HER2- Hormonal Therapy 12/16/2017 Faslodex (fulvestrant) Targeted Therapy 2/15/2018 Verzenio Chemotherapy 7/28/2018 Xeloda (capecitabine) Hormonal Therapy Femara (letrozole)
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Nov 25, 2018 05:22PM Wanderingneedle wrote:

Hi, Karen,

Sorry the Xeloda is no longer working for you. I felt that way with Ibrance/letrozole - no huge SE’s. I believe losing your hair is a common side effect, along with nausea. You MO can give you meds for that. I quit taking blood pressure meds because I was getting dizzy and lightheaded for about 4 days after treatment. I still get a little dizzy but not as bad. Rest when you’re tired - sometimes all you need is to rest a bit and keep going. Take care of yourself!I don’t know if it’s a side effect but I’m crankier than usual!

Libby - Just trying to figure it all out and keep up with daily life. Dx 11/9/2017, IDC, Right, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- (IHC) Hormonal Therapy 1/22/2018 Femara (letrozole) Targeted Therapy 1/22/2018 Ibrance (palbociclib) Chemotherapy 9/13/2018 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 2/11/2019 Doxil (doxorubicin) Hormonal Therapy 2/12/2019 Faslodex (fulvestrant) Chemotherapy 2/26/2019 Halaven (eribulin)
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Nov 29, 2018 09:43AM HLB wrote:

Hello everyone! I just started abraxane Monday. Last night I started feeling numerous aches and pains, not real bad, but one of them is in the lower abdomen, I think near the the bladder. It's like sharp twinges. I do have a small amount of ascites. I'm a little concerned about peritonitis but just wondering if this is common side effect of abraxane. Thanks for any insight. I have to get ready for work so I did not read any of this thread yet but I will. 

Dx 10/2004, IDC, 1cm, Stage IIA, Grade 2, 2/11 nodes, ER+/PR+, HER2- Surgery 10/30/2004 Lumpectomy: Left; Lymph node removal: Left, Sentinel Surgery 11/30/2004 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 1/2/2005 AC + T (Taxol) Surgery 9/15/2005 Reconstruction (left); Reconstruction (right) Dx 7/23/2012, IDC, Stage IV Hormonal Therapy 7/23/2012 Femara (letrozole) Hormonal Therapy 4/1/2015 Aromasin (exemestane)
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Nov 29, 2018 09:50AM GracieM2007 wrote:

HLB, I don't know about ascites, but my pain level went up the first few months of abraxane. I think it was tumor flare. Do you think you might have had a small spot in that area? If it doesn't get better you might check with your oncology nurse. Hope it goes away for you! I'm the good side, Abraxane kicked the back out of my cancer. Brought one tumor market down to normal limits, the other one down hundreds. I'm on a three week break after month five due to growing neuropathy! Will probably go back in it, for however long it works.

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Nov 29, 2018 09:33PM HLB wrote:

Thanks Gracie, I am hoping it's tumor flare. As of right now, we don't know why I have ascites so it's possible. It got worse throughout the day so I called onc, who sent me for urinalysis, gave me some Ultram, and I will see him tomorrow. I usually try to avoid appts if at all possible but I don't want to take chances with peritonitis. Plus the ascites is messing with my head.

Dx 10/2004, IDC, 1cm, Stage IIA, Grade 2, 2/11 nodes, ER+/PR+, HER2- Surgery 10/30/2004 Lumpectomy: Left; Lymph node removal: Left, Sentinel Surgery 11/30/2004 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 1/2/2005 AC + T (Taxol) Surgery 9/15/2005 Reconstruction (left); Reconstruction (right) Dx 7/23/2012, IDC, Stage IV Hormonal Therapy 7/23/2012 Femara (letrozole) Hormonal Therapy 4/1/2015 Aromasin (exemestane)
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Dec 3, 2018 07:46PM Tychad wrote:

Hi. I was wondering what neuropathy is. (If I spelled it right). I’m not sure if that’s what I have with my feet. They hurt and are swollen and feel tight and sometimes it feels like pins and needles in it. Thank

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Dec 3, 2018 08:09PM GracieM2007 wrote:

Sounds like neuropathy. Tingling, pins and needles, feet feel like sandpaper, mine ache badly. Mine don't swell at all though.

dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Dec 4, 2018 06:53PM Tychad wrote:

Thanks for the info. But what do you do about it. Did you tell your doctor. Thanks Rhonda

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Dec 5, 2018 12:39PM - edited Dec 5, 2018 09:12PM by GracieM2007

yes, do tell your oncologist. They can adjust your dose or give you something to help. L Glutimine (sp?) Can help. Use the powder form and mix in with a non acid drink. 30 grams a day. I did 10 grams three times a day. Also B12 can help. Ask your oncologist how much to take.Hope that helps a little!


dx 4/11/2007, rt. mast 4/27/2007, 1.7cm IDC, stage 2, Grade 3, 1.4cm tumor in one node,, ER/PR+, Her2-, 4 DD AC, 4 DD T, Arimidex/ 2016 mets to bone, extensive. Femera, Xgeva. 1/18 Faslodex, Ibrance. July 2018, Abraxane.
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Dec 10, 2018 09:14PM Tychad wrote:

hi. What are the side effects of neraphy. And what are you taking to help it’ll thanks rhond

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Dec 11, 2018 10:16AM HLB wrote:

Do most people lose their hair on this treatment? I just had my 3rd and no hair loss. I've kind of been looking fwd to it because my hair is crap from the treatments I've been on lol.

Dx 10/2004, IDC, 1cm, Stage IIA, Grade 2, 2/11 nodes, ER+/PR+, HER2- Surgery 10/30/2004 Lumpectomy: Left; Lymph node removal: Left, Sentinel Surgery 11/30/2004 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 1/2/2005 AC + T (Taxol) Surgery 9/15/2005 Reconstruction (left); Reconstruction (right) Dx 7/23/2012, IDC, Stage IV Hormonal Therapy 7/23/2012 Femara (letrozole) Hormonal Therapy 4/1/2015 Aromasin (exemestane)

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