We are 195,033 members in 81 forums discussing 144,133 topics.

Help with Abbreviations

All TopicsForum: Stage IV and Metastatic Breast Cancer ONLY → Topic: Unfortunately things are going downhill

Topic: Unfortunately things are going downhill

Forum: Stage IV and Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Jan 11, 2017 09:34PM

Kandy wrote:

Funny how this crap can change so quickly. Up until September, I had one lonely bone met. Since then, it seems to be on the run. I had several new bone mets in September with one liver met. I was switched to Afinitor and Aromasin. For 2 months my markers were dropping and we were all excited. At the end of December I had a pet scan that showed progression. My oncologist said we were going to hold off and see if A/A would kick in. Then my tumor markers started rising again and I am having quite a bit of pain. Overall, not doing well. So today oncologist said, it's not working. So sad. He wanted to start giving me Abraxane, we will start that next week. Also, scheduled me to have my port put back in, I thought I was done the first time and had it removed. I am so sad over the news. I feel like this is really the beginning of the end. I really would love to have more time and just want Harper to be able to remember me. I knew that this would happen at some point, but I really wasn't prepared for it to move so quick. Dang it. I wish all of you the best. I pray that someday a cure will be found and no one will have to go through this again.

Dx 1/20/2009, IDC, 1cm, Stage IIIA, Grade 3, 4/9 nodes, ER+/PR+, HER2- Surgery 2/25/2009 Lumpectomy: Left; Lymph node removal: Left, Underarm/Axillary Chemotherapy 3/8/2009 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Gemzar (gemcitabine), Navelbine (vinorelbine) Radiation Therapy 10/6/2009 Breast, Lymph nodes Hormonal Therapy 1/3/2010 Arimidex (anastrozole) Dx 10/31/2013, IDC, Stage IV, Grade 3, ER+/PR+, HER2- Radiation Therapy 11/17/2013 3DCRT: Bone Hormonal Therapy 12/2/2013 Faslodex (fulvestrant) Targeted Therapy 10/7/2016 Afinitor (everolimus) Hormonal Therapy 10/31/2016 Aromasin (exemestane) Chemotherapy 2/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 5/8/2017 Carboplatin (Paraplatin) Chemotherapy 8/14/2017 Halaven (eribulin) Targeted Therapy
Log in to post a reply

Page 1 of 27 (795 results)

Posts 1 - 30 (795 total)

Log in to post a reply

Jan 11, 2017 10:06PM jensgotthis wrote:

I am so sorry to hear of your progression. I hope the chemo is the key to getting a handle on it and that you're back to a more stable place. If can change in an instant and I'm going to send lots of good thoughts that yours changes back and you get lots more time

Jennifer, 42, Los Angeles Dx 12/3/2015, IDC: Tubular, Left, 2cm, Stage IV, metastasized to bone, Grade 1, 0/12 nodes, ER+/PR+, HER2- Chemotherapy 1/4/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 5/1/2016 External: Bone Hormonal Therapy 5/23/2016 Surgery 5/25/2016 Lymph node removal: Left; Mastectomy: Left Targeted Therapy 9/14/2016 Ibrance (palbociclib) Hormonal Therapy 9/14/2016 Femara (letrozole) Radiation Therapy Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy
Log in to post a reply

Jan 11, 2017 10:12PM Kjones13 wrote:

oh kandy! I'm so sorry things are progressing so quickly. I bet that is really scary. I was dx stage 4 from the get go so I knew my port was in for the long haul. Having it put back in is such a strong reminder that things aren't going the way you planned. But don't you hang your hat up just yet. I know you know many of the ladies on here who found the right combo and things are back under control! Today sucked. No doubt about it. Take some days to rant, have a pity party, whatever you need to do...then you pick yourself up and kick some cancer ass! We are here for you. And that baby will know you because you are going to fight like hell to be here

James 1:2-4 Dx 9/14/2012, IDC, 6cm+, Stage IV, Grade 3, 11/11 nodes, mets, ER+/PR-, HER2+ Surgery 10/9/2012 Lymph node removal: Right, Sentinel Targeted Therapy 10/17/2012 Herceptin (trastuzumab) Targeted Therapy 10/17/2012 Perjeta (pertuzumab) Chemotherapy 10/17/2012 Taxol (paclitaxel) Hormonal Therapy 3/1/2013 Surgery 10/24/2013 Mastectomy: Right
Log in to post a reply

Jan 11, 2017 10:57PM Madelineg wrote:

You have my Prayers. You know things can change in a instant and you could be stable again. Do not give up. I started with Stage 4 so I knew I was in for the long haul. I know someone that had stage ,4 melonima and it's ,13 years later and the meanie is still alive.He told a friend that I was going to die and I did just the opposite with him.

Dx 5/25/2016, Left, 5cm, Stage IV, metastasized to bone, Grade 1, ER+, HER2- Surgery 12/3/2016 Mastectomy: Left Radiation Therapy 12/5/2016 Whole-breast: Breast Hormonal Therapy Aromasin (exemestane) Radiation Therapy External: Bone
Log in to post a reply

Jan 11, 2017 10:58PM Southernsurvivor wrote:

Kandy - I too am sorry to hear this! Ditto what Kjones said. We know things can change so quickly. I was on death's door in early 2015 and I'm still here kicking and screaming 2 years later. Up, down, up down - hate this seesaw we are on! Give yourself a bit of time to wallow in this, and then dust yourself off and get back to loving on that baby! We are definitely here for you.

A big virtual hug to you tonight!

Sheri
Log in to post a reply

Jan 11, 2017 11:27PM Beatmon wrote:

Kandy, so very sorry to hear about your progression. I bet that the change will knock those tumor markers back down. I know that you love him so much. If strong will can do the trick, you will come out with a lot more time with the baby. Brenda

Dx 7/27/2012, IDC, <1cm, Stage IA, Grade 3, 0/1 nodes, ER-/PR-, HER2+ Surgery 8/9/2012 Lymph node removal: Left, Sentinel; Mastectomy: Left, Right Surgery 12/1/2013 Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery 7/1/2014 Reconstruction (left); Reconstruction (right) Dx 8/9/2014, IDC, Both breasts, Stage IV, metastasized to lungs, Grade 3, ER-/PR-, HER2+ Targeted Therapy 8/27/2014 Herceptin (trastuzumab) Targeted Therapy 8/27/2014 Perjeta (pertuzumab) Chemotherapy 8/27/2014 Taxotere (docetaxel)
Log in to post a reply

Jan 12, 2017 12:26AM Nan812 wrote:

hi Kandy,

I too was diagnosed from the start with stage 4 and it seems like every day I hear of someone who is stage 4 @ 12 and13 years and still fighting. My doc told me " no, we can't cure it, it's more like a chronic condition that needs to be managed like diabetes". This is just what we do...we somehow manage to fight...why?...because we love

You are all in my heart

DX 03/13/15;stg4;TN;BRAC1; both breasts,lymph,lungs,bones,adrenal,spleen,brain; 8moths chemo,Abraxane /Cytoxan/Adriamycin 2015; gammaknife 5 brain tumors 2015; GK 1 brain 2016; Rad/adrenal 2016; craniotomy2017; GK2017,havalen & lymparza2017
Log in to post a reply

Jan 12, 2017 12:37AM jensgotthis wrote:

Kandy, have you discussed getting a new biopsy done to see if your receptor typenhas changed

Jennifer, 42, Los Angeles Dx 12/3/2015, IDC: Tubular, Left, 2cm, Stage IV, metastasized to bone, Grade 1, 0/12 nodes, ER+/PR+, HER2- Chemotherapy 1/4/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 5/1/2016 External: Bone Hormonal Therapy 5/23/2016 Surgery 5/25/2016 Lymph node removal: Left; Mastectomy: Left Targeted Therapy 9/14/2016 Ibrance (palbociclib) Hormonal Therapy 9/14/2016 Femara (letrozole) Radiation Therapy Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy
Log in to post a reply

Jan 12, 2017 01:11AM ShetlandPony wrote:

Kandy, it looks like it has been eight years since you had any chemo. That damned cancer won't know what hit it. Don't give up hope. Sending caring thoughts your way.

2011 Stage I ILC ER+PR+ Her2- 1.5 cm grade 1, ITCs sn. Lumpectomy, radiation, tamoxifen. 2014 Stage IV ILC ER+PR+Her2- grade 2, mets to breast, liver, retroperitoneal nodes. Taxol NEAD. 2015,2016 Ibrance+letrozole. 2017 Faslodex+Afnitor; Xeloda
Log in to post a reply

Jan 12, 2017 02:09AM Kandy wrote:

Thanks for all the warm wishes. I really need a picker upper. It is 3 in the morning and I can't sleep. It's like I'm trying to figure out every issue that will arise after I'm not here and find an answer so my family doesn't have to figure it out. Grrrr, got to love how the mind works. I am a planner and I feel like I have to figure everything out for them, after all I have always made it easy for them up to now. I just don't want them to not have some good alternatives. Anyway thanks again for everyone caring.

I did have another biopsy on the second lesion in September. It was still estrogen positive but progesterone negative, her2 negative.

Dx 1/20/2009, IDC, 1cm, Stage IIIA, Grade 3, 4/9 nodes, ER+/PR+, HER2- Surgery 2/25/2009 Lumpectomy: Left; Lymph node removal: Left, Underarm/Axillary Chemotherapy 3/8/2009 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Gemzar (gemcitabine), Navelbine (vinorelbine) Radiation Therapy 10/6/2009 Breast, Lymph nodes Hormonal Therapy 1/3/2010 Arimidex (anastrozole) Dx 10/31/2013, IDC, Stage IV, Grade 3, ER+/PR+, HER2- Radiation Therapy 11/17/2013 3DCRT: Bone Hormonal Therapy 12/2/2013 Faslodex (fulvestrant) Targeted Therapy 10/7/2016 Afinitor (everolimus) Hormonal Therapy 10/31/2016 Aromasin (exemestane) Chemotherapy 2/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 5/8/2017 Carboplatin (Paraplatin) Chemotherapy 8/14/2017 Halaven (eribulin) Targeted Therapy
Log in to post a reply

Jan 12, 2017 02:37AM Bad_At_Usernames wrote:

I'm a planner and I like having alternatives too. Being in NC, you have access to some great medical facilities. Do you already go to a NCI center?

For me, I like to keep lists of clinical trials, treatments and specialists that may be of use to me in the future. Have you had Foundation One/Guardant testing done? I'm stable on standard treatment at the moment, but if/when things get more interesting in the future, I plan to seek out the best precision medicine has to offer me based on my results.

It sounds like you still have a relatively low tumor load and have many more lines of treatment available, so remember that. People have bounced back from much worse situations than you are in now

"...to survive this disease, you had to be an eternal optimist and very aggressive..." -Vince DeVita Dx 12/23/2013, IDC, 6cm+, Stage IIIC, Grade 3, ER+/PR+, HER2+ Chemotherapy 1/16/2014 AC + T (Taxol) Targeted Therapy 3/16/2014 Perjeta (pertuzumab) Targeted Therapy 3/17/2014 Herceptin (trastuzumab) Surgery 7/11/2014 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left Radiation Therapy 8/28/2014 Breast, Lymph nodes Targeted Therapy 9/22/2014 Kadcyla (T-DM1, ado-trastuzumab) Hormonal Therapy 11/17/2014 Zoladex (goserelin) Hormonal Therapy 1/31/2015 Femara (letrozole) Dx 1/7/2016, IDC, Stage IV, metastasized to brain Radiation Therapy 7/27/2016 External: Brain Targeted Therapy 11/15/2016 Tykerb (lapatinib) Dx 3/23/2017, IDC, Stage IV, metastasized to liver Chemotherapy 3/28/2017 Xeloda (capecitabine)
Log in to post a reply

Jan 12, 2017 03:11AM Heidihill wrote:

Ditto what Bad_at said. Chemo could mean a new beginning, especially with progesterone receptor negative, and the port would make it happen with greater ease. Sending hugs.

Dx 8/2007, IDC, Left, 2cm, Stage IV, metastasized to bone, Grade 2, 2/19 nodes, mets, ER+/PR+, HER2- (FISH) Hormonal Therapy 3/24/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
Log in to post a reply

Jan 12, 2017 04:34AM Lynnwood1960 wrote:

Kandy, I wish I had the magic words to take all of this stress away. Just know that I am sending you prayers and good thoughts during this difficult time. Hoping your next treatment will knock those mets back.

Dx 4/6/2015, ILC, Right, 3cm, Stage IV, Grade 2, 0/12 nodes, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib)
Log in to post a reply

Jan 12, 2017 05:04AM Noni wrote:

I love all the wonderful, positive words others have shared. What a treasure of experience and insight.

Kandy, I'm sorry about the progression. It's always a slap in the face to get such bad news. Please remember, as the others have said we are faced with years of ups and downs. You're heading in for a fight, but we'll be here to cheer you on and hold your hand.

Noni, 50 year old mother of an 11 year old brainy girl. Taking a break from BCO for a while. Now on hospice. Dx 12/5/2007, DCIS, <1cm, Stage 0, Grade 3, 0/6 nodes Dx 11/13/2015, IDC, Both breasts, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 12/10/2015 Taxol (paclitaxel) Hormonal Therapy 3/30/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/5/2016 External: Bone Chemotherapy 12/4/2016 Doxil (doxorubicin) Chemotherapy 2/28/2017 Adriamycin (doxorubicin)
Log in to post a reply

Jan 12, 2017 06:13AM Fitztwins wrote:

I am a planner too. I too always look at clinical trials and new drugs out there. (Personally...I am de-cluttering right now and again getting my finances in order-lol)

I have been dancing with this disease for 12+ years and mets for over 8+,

I can't tell you how many times I have had progression. Even had a fracture in my femur this past summer and I thought, thats it, I am done, this is the big downhill slide...but then things stabilize ....I have been on chemo 4x - lost my hair 4 times? on my last hormonal....(I am a triple +++)

I am still here, mainly stable. Yes, you have had progression, crappy that you now have pain and that one liver met. You are not out of options. What about IBRANCE? you maybe be the perfect candidate. Or a clinical trial. This isn't your hail mary treatment.

So, what you have is what I call progression depression. I know it well. I give myself a little time to grieve, then I get my cancer fighting cape and get back up. Today is a new day, and you are not out yet. You have many more good days, months, and years ahead of you. Its a marathon.

onward and upward. deep breath. you can do this my friend.


Janis

Enjoy Every Sandwich. Dx 12/12/2004, IDC, Left, 3cm, Stage IV, metastasized to bone/lungs, Grade 2, mets, ER+/PR+, HER2+ (FISH) Surgery 1/18/2005 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left; Reconstruction (left): Free TRAM flap Chemotherapy 1/31/2005 AC + T (Taxol) Radiation Therapy 4/30/2005 Breast, Lymph nodes Targeted Therapy 5/31/2005 Herceptin (trastuzumab) Hormonal Therapy 12/31/2005 Femara (letrozole) Hormonal Therapy 6/1/2008 Aromasin (exemestane) Targeted Therapy 6/30/2008 Herceptin (trastuzumab) Hormonal Therapy 6/14/2013 Arimidex (anastrozole) Targeted Therapy 9/4/2015 Perjeta (pertuzumab)
Log in to post a reply

Jan 12, 2017 06:23AM Kandy wrote:

Janis, my oncologist did say if I really wanted to, he would agree to ibrance. But his thoughts was that he really didn't think it would work. And every time we try something it takes several months before we can determine if it's working, at that point my cancer seems to be severely on the run and has caused multiple new mets and potentially has invaded a new organ. He said because mine is so aggressive, he felt at this point we should do what he thinks will surely work. I agreed, in fear that the next time would be extremely worse just like this time. So, is it possible that I won't stay on chemo now till the end? I figured once I went there he wouldn't go back. Let me know your thoughts. You have done awesome for 8 years. Two thumbs up for sure.

Dx 1/20/2009, IDC, 1cm, Stage IIIA, Grade 3, 4/9 nodes, ER+/PR+, HER2- Surgery 2/25/2009 Lumpectomy: Left; Lymph node removal: Left, Underarm/Axillary Chemotherapy 3/8/2009 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Gemzar (gemcitabine), Navelbine (vinorelbine) Radiation Therapy 10/6/2009 Breast, Lymph nodes Hormonal Therapy 1/3/2010 Arimidex (anastrozole) Dx 10/31/2013, IDC, Stage IV, Grade 3, ER+/PR+, HER2- Radiation Therapy 11/17/2013 3DCRT: Bone Hormonal Therapy 12/2/2013 Faslodex (fulvestrant) Targeted Therapy 10/7/2016 Afinitor (everolimus) Hormonal Therapy 10/31/2016 Aromasin (exemestane) Chemotherapy 2/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 5/8/2017 Carboplatin (Paraplatin) Chemotherapy 8/14/2017 Halaven (eribulin) Targeted Therapy
Log in to post a reply

Jan 12, 2017 07:44AM - edited Jan 20, 2017 07:52AM by sharethehope

This Post was deleted by sharethehope.
Log in to post a reply

Jan 12, 2017 07:50AM linda714 wrote:

Please try the Ibrance with either letrozole or the butt shots (flasodex). It has worked for so many. I was on it 23 cycles in trial. Got me Ned immediately, now on letrozole alone.

Log in to post a reply

Jan 12, 2017 08:18AM Moissy wrote:

Kandy -I'm sorry to hear about the progression. I know those times at night when we're trying to figure things out can be rough--especially if you are having pain right now. Janis' term of "progression depression" is such a good descriptor. If you decide on chemo, results should come more quickly than some of the other meds you've been on so far. Hoping your new plan is in place soon so you will start feeling better.

Dx 2004, IDC, 6cm+, Grade 2, 0/1 nodes, ER+, HER2- Dx 2015, Stage IV, ER+/PR+, HER2- Chemotherapy AC + T (Taxotere) Hormonal Therapy Arimidex (anastrozole) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole) Radiation Therapy Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
Log in to post a reply

Jan 12, 2017 08:30AM kayrnic wrote:

Progression is the absolute worst. I know you automatically start thinking the end is near! But don't give up! The next treatment could put you right back to NED! Sending love and hugs!

Kay ---bone mets Dx 11/14/2001, IDC, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2- Dx 3/9/2012, IDC, Stage IV, mets, ER+/PR+, HER2-
Log in to post a reply

Jan 12, 2017 08:37AM sueopp wrote:

Thinking of you Kandy, and sending all my good karma your way. It's that cha-cha again: one step back, two steps forward. We areall standing with you. Fondly, SUE

Dx 12/2010, IDC, Stage IV, 26/35 nodes, mets, ER-/PR-, HER2+
Log in to post a reply

Jan 12, 2017 09:22AM 50sgirl wrote:

Kandy, Bummer! Progression is never welcome, but it sounds like your MO has a plan for you. I think that chemo will start working more quickly than Ibrance and Faslodex or Letrozole, and that is probably why your doctor has recommended it for you. That does not mean that you will be on chemo forever. Once those cancer cells are under control, your doctor can reassess the situation and might recommend something else. There are still many other treatments out there. You have been through a lot in the past year. It is understandable to feel the way you do now. Anyone who has seen progression, even without all the other challenges you have been through during the past year, would feel the same way. I do like Janis' term of "progression depression". It describes the feelings perfectly. Do what you need to do. Cry, rant, scream, have a big piece of chocolate cake and a glass of wine. It takes a while to adjust to the fact that things have progressed, but believe me, eventually you will adjust, and you will realize that this is just another bump in a road full of pot holes. You seem to receive great support from your family, and we will always be here for you, too. Planning for the future is never a bad thing, but be prepared to change plans often. My plan at diagnosis more than a year and a half ago and then again when things progressed to my liver 6 months ago was to bow out quietly and gracefully because I thought things would end quickly. Well, here I am now feeling healthy as a horse, and I am anything but quiet and no where ready to bow out. My liver mets are"less conspicuous", and I am loving life. I will keep you in my prayers.

Hugs from, Lynne

Dx 6/5/2015, IDC, Left, 3cm, Stage IV, metastasized to bone, Grade 1, ER+/PR+, HER2- (FISH) Hormonal Therapy 6/25/2015 Arimidex (anastrozole) Dx 8/9/2016, IDC, Left, 3cm, Stage IV, metastasized to bone/liver, Grade 1, ER+/PR+, HER2- Hormonal Therapy 8/10/2016 Faslodex (fulvestrant) Targeted Therapy 8/31/2016 Ibrance (palbociclib)
Log in to post a reply

Jan 12, 2017 10:39AM SusanR wrote:

I'm hearing you Kandy!  After 5 wonderful years on Faslodex, I just found out I have significant progression of bone mets.  I'm now on round 2 of Ibrance and Letrazole.  I'm going through some rough "progression depression" (thanks for the term Fitz!) right now myself and feel the need to talk myself off the ledge at any given moment.  

We can do this!!!  I am a planner and can't deal with the fact that I am really not in control here, but I'm spending some quiet time to get it in perspective.  Who says our newest treatment plan can't work for us?  Who says we are doomed?  I'm going to remain hopeful that our new treatment is going to kick this cancer to the curb and keep us going for a long time!  

Hang in there Kandy.  There is so much love and support to be gotten from this wonderful group of women!!

SusanR

IDC 2002 Stage II Grade 3 4/29 nodes ER/PR+ Her2- Stage IV Dec 2008 Bone ER+/PR-/Her2- Bone Progression Oct.2011 to Spine,Skull and Rib Dx 11/22/2002, IDC, Stage IIIC, Grade 3, 4/29 nodes, mets, ER+/PR+, HER2- Surgery 11/25/2002 Lumpectomy: Right; Lymph node removal: Right, Sentinel; Mastectomy: Left, Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Chemotherapy 1/7/2003 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Chemotherapy 1/7/2003 Adriamycin (doxorubicin) Chemotherapy 1/7/2003 Cytoxan (cyclophosphamide) Radiation Therapy 7/5/2003 Breast Radiation Therapy 1/20/2009 Bone Hormonal Therapy 10/10/2011 Faslodex (fulvestrant) Targeted Therapy 12/1/2016 Ibrance (palbociclib)
Log in to post a reply

Jan 12, 2017 10:50AM AmyQ wrote:

Kandy,

When one of our members suffers progression, we all suffer progression. I'm so sorry this is happening and seemingly so quickly but I agree IV chemo most likely will get a faster response. Prayers for you and for a treatment that gets you back dancing with NED.

Hugs -

Amy

Dx 2/7/2013, IDC, 1cm, Stage IV, Grade 2, 2/3 nodes, mets, ER+/PR+, HER2- Chemotherapy 4/8/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 7/18/2013 Femara (letrozole) Radiation Therapy 11/24/2015 External: Bone Hormonal Therapy 1/9/2016 Faslodex (fulvestrant)
Log in to post a reply

Jan 12, 2017 11:11AM Tina2 wrote:

Kandy,

I'm so sorry. Clearly your doc knows your situation and fears the progression will rage out of control without using the big guns. Under the circumstances, I'd go with your doc's recommendation. Knock the damned cancer senseless with chemo, then regroup to consider a less harsh treatment.

Please don't assume things are going downhill because of this setback. Read and re-read the experiences described above. Many women here have been on this roller coaster for a long, long time, and are living well.

By your side,

Tina


Stage I, 1985, modified radical mastectomy; Stage I, 1995, modified radical mastectomy;Stage IV, lung mets, ER+/PR+; treated with Faslodex since July, 2011 Dx Stage IV, mets, ER+/PR+
Log in to post a reply

Jan 12, 2017 02:05PM BabyRuth wrote:

So sorry to hear of the progression Kandy. Hearing those words are horrible and no matter what you can not totally prepare for the outcome. I hope your MO comes up with a plan you are confident in and if not go for a second opinion. It is always good to consider your options before you make your decision. Sending many prayers your way!

Dx 12/29/2008, IDC, 2cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2+ Targeted Therapy 1/9/2009 Herceptin (trastuzumab) Chemotherapy 3/18/2009 Carboplatin (Paraplatin), Taxotere (docetaxel) Dx 4/23/2012, IDC, Grade 2, ER+/PR+, HER2+ Dx 5/13/2013, IDC, 2/2 nodes, ER+/PR+, HER2+ Chemotherapy 9/11/2013 Taxol (paclitaxel) Dx 6/26/2015, IDC, 1cm, Stage IV, ER+/PR+, HER2+ (FISH) Chemotherapy 7/15/2015 Taxotere (docetaxel) Targeted Therapy 7/15/2015 Herceptin (trastuzumab) Targeted Therapy 7/15/2015 Perjeta (pertuzumab) Hormonal Therapy Faslodex (fulvestrant)
Log in to post a reply

Jan 12, 2017 02:21PM Kandy wrote:

Big thanks to all of you wonderful ladies. What a great group to be affiliated with, everyone joins together to try to lift someone up. Progression depression is a great term, thanks Janis. Depressed is probably the understatement. The last 18 months have sucked. First the acetabulum fracture, can't walk for 6 months, literally thought that would drive me crazy, finally someone agrees to do a 10 hour major surgery that they are not sure I will live through it, then recovery time, finally I'm starting to walk again and low and behold my tumor markers start doubling every month. So in less than 6 months I go from Ned to too many lesions to even name, plus the liver, oh and the adrenal gland has been added. Anyone else out there have mets there? Leave it to me to put it everywhere. I just would like a small fraction of time that I felt good again, I have forgotten what that was like. My world has definitely been rocked, more like turned over. It's hard for me to think it's moving so quick and very scary. I do wish each and every one of you only the best. Y'all rock

Dx 1/20/2009, IDC, 1cm, Stage IIIA, Grade 3, 4/9 nodes, ER+/PR+, HER2- Surgery 2/25/2009 Lumpectomy: Left; Lymph node removal: Left, Underarm/Axillary Chemotherapy 3/8/2009 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Gemzar (gemcitabine), Navelbine (vinorelbine) Radiation Therapy 10/6/2009 Breast, Lymph nodes Hormonal Therapy 1/3/2010 Arimidex (anastrozole) Dx 10/31/2013, IDC, Stage IV, Grade 3, ER+/PR+, HER2- Radiation Therapy 11/17/2013 3DCRT: Bone Hormonal Therapy 12/2/2013 Faslodex (fulvestrant) Targeted Therapy 10/7/2016 Afinitor (everolimus) Hormonal Therapy 10/31/2016 Aromasin (exemestane) Chemotherapy 2/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 5/8/2017 Carboplatin (Paraplatin) Chemotherapy 8/14/2017 Halaven (eribulin) Targeted Therapy
Log in to post a reply

Jan 12, 2017 02:27PM Iwrite wrote:

Kandy,

Sending you hugs and totally onboard with some meds so you can sleep between planning sessions. I agree with the others that there are other treatments available. It may be that chemo will knock it back and then Ibrance will get you back to NED.

Get another opinion if you need to! We are all thinking of you and understand the progression fears. Hug Harper! You have more living to do!

Kathryn Dx 11/2/2015, ILC, Both breasts, 6cm+, Stage IV, metastasized to brain/bone, ER+/PR+, HER2- Hormonal Therapy 11/5/2015 Femara (letrozole) Targeted Therapy 11/11/2015 Ibrance (palbociclib)
Log in to post a reply

Jan 12, 2017 03:21PM Fitztwins wrote:

Honestly, if you haven't been on a chemo for a few years, yeah, I would jump on abraxane to Knock that crap back and then add ibrance.

Just my opinion. Good luck, it sucks, you can do this!

Enjoy Every Sandwich. Dx 12/12/2004, IDC, Left, 3cm, Stage IV, metastasized to bone/lungs, Grade 2, mets, ER+/PR+, HER2+ (FISH) Surgery 1/18/2005 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left; Reconstruction (left): Free TRAM flap Chemotherapy 1/31/2005 AC + T (Taxol) Radiation Therapy 4/30/2005 Breast, Lymph nodes Targeted Therapy 5/31/2005 Herceptin (trastuzumab) Hormonal Therapy 12/31/2005 Femara (letrozole) Hormonal Therapy 6/1/2008 Aromasin (exemestane) Targeted Therapy 6/30/2008 Herceptin (trastuzumab) Hormonal Therapy 6/14/2013 Arimidex (anastrozole) Targeted Therapy 9/4/2015 Perjeta (pertuzumab)
Log in to post a reply

Jan 12, 2017 03:31PM LindaE54 wrote:

Kandy, I silently followed you on the A/A thread, your major surgery and I'm so sorry to read your latest news. You've been through hell these past 18 months and now facing new challenges. It really sucks. You are in my thoughts and prayers. I'm glad your MO has a new plan for you with Abraxane. Things can go downhill quickly but can also turn in the other direction quickly. This is my wish for you. I like that your MO is on top of things and reacts promptly. Sending much love and hugs. We are all rooting for you.

Linda - dx at 54 Dx 11/26/2013, IDC, Left, 1cm, Stage IV, metastasized to bone/liver/other, Grade 3, mets, ER+/PR+, HER2- Radiation Therapy 12/19/2013 External: Bone Hormonal Therapy 12/30/2013 Femara (letrozole) Hormonal Therapy 5/28/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 5/29/2014 External: Bone Radiation Therapy 8/28/2014 External: Bone Hormonal Therapy 9/25/2014 Femara (letrozole) Radiation Therapy 12/14/2014 External: Bone Hormonal Therapy 2/17/2017 Faslodex (fulvestrant) Chemotherapy 5/15/2017 Taxol (paclitaxel) Radiation Therapy 6/5/2017 External: Bone Chemotherapy 10/3/2017 Ellence (epirubicin) Chemotherapy 10/23/2017 CEF
Log in to post a reply

Jan 12, 2017 03:32PM ShetlandPony wrote:

Beat it back with chemo, then hold the line with hormonal treatment is the strategy my onc used for me. I think that because cancer mutates to adapt, alternating treatments is a strategy that makes sense.

2011 Stage I ILC ER+PR+ Her2- 1.5 cm grade 1, ITCs sn. Lumpectomy, radiation, tamoxifen. 2014 Stage IV ILC ER+PR+Her2- grade 2, mets to breast, liver, retroperitoneal nodes. Taxol NEAD. 2015,2016 Ibrance+letrozole. 2017 Faslodex+Afnitor; Xeloda

Page 1 of 27 (795 results)