  The Chairman of the Nutritional Sciences Department and the Director of the NIH Cancer Research Program at UC Berkeley have recently discovered that Diindolylmethane (DIM) from Brassica vegetables is a potent activator of the immune response system. ActivaMune has been launched with technology exclusively licensed from UC Berkeley as a natural immune system booster and fundraiser for their ongoing nutrition-based cancer prevention research. ActivaMune contains Bioavailable Diindolylmethane (DIM) at a clinically efficacious dosage along with other important nutrients that boost the immune system and support multiple organs throughout the body: Lycopene, Lutein, Zeaxanthin, Sulforaphane, Selenium, Calcium and Vitamins C, D3 and E.
ActivaMune is a patented DIM supplement and natural immune system booster. Its most important and differentiating attribute as a dietary supplement is that, in a safe and natural way, it increases the sensitivity of cells in the body to the Interferon-Gamma protein (IFN-G). Interferon-Gamma is the key signaling protein within the immune system that enhances the ability of the body to defend itself.
In addition to inducing Interferon-Gamma sensitivity, DIM also stimulates the production of the Granulocyte Colony Stimulating Factor (G-CSF) which is directly responsible for White Blood Cell production in the body, Interlukin-6 (IL-6), which is an important immune enhancing cytokine, and Interlukin-12 (IL-12) which stimulates the growth and function of T-Cells. Due to this important discovery at UC Berkeley, biomedical investigators worldwide have begun investigating Diindolylmethane (DIM) as a natural occurring therapeutic candidate for a variety of conditions, including numerous forms of cancer, infectious diseases and acne. In 2013, Scientists in Germany published a seminal discovery demonstrating how Diindolylmethane (DIM) also helps to slow down the aging process and promote life extension at the cellular level. This discovery further elevates the importance and multi-functional capabilities of this important phytonutrient from Brassica vegetables (broccoli, cauliflower, Brussels sprouts, kale). Achieving clinically relevant dosages of this compound from Brassica vegetables requires that one consume approximately five pounds of raw uncooked Brassica vegetables per day. Cooking Brassica vegetables destroys the enzyme necessary for the production of Diindolylmethane (DIM). Hence, dietary supplementation with ActivaMune is recommended by physicians keeping up with recent developments in the fields of clinical nutrition and applied molecular biology. |
Treating estrogen responsive cancer naturally
Comments
-
Hi Enerva
Yes Vit D3 is the answer. If your diet is good I understand that Calcium tablets are unnecessary and could affect your arteries deleteriously. I recently read, but have not got my act together to order myself any but, Vit K2 is supposed to be good for bones and joints. HTH
Mothering Sunday here in the UK - saw one of my daughters. So yes, lovely w/e thanks
0 -
.
0 -
.0
-
i ll look for this book.
Thanks
0 -
Another book that you all may be interested in:
The Anti-Estrogenic Diet: How Estrogenic Foods and Chemicals Are Making You Fat and Sick by Hofmekler, Ori
Sorry about the big print there! The one suggestion he made that really popped out at me is to get that belly fat off. I have a very pronounced apple shape and when dx'ed I was 44 lbs overweight--down 22 now though--woo hoo! Belly fat is very metabolically active and not in a good way and will help your body keep pumping out more estrogen and a pot belly is often a sign of unbalanced hormones--moreso than a pear shape that is. Sugar will of course contribute to this and I have a major sweet tooth. I'm off that altogether--haven't even cut down--it's gone. Then if you eat too much sugar and have too much belly fat, you often have a fatty liver and the liver is what helps get the "waste estrogen" out of your body--unless it's not working at full speed. I might also add that belly fat is inflammatory to the system.
I knew about the belly fat being metabolically active already when I went to see the plastic surgeon and after asking some questions, decided I will not do a DIEP flap. I have enough fat to make some big ole' boobies, but I want to get it all off, due to the estrogen producing nature of it. For some people who don't have a lot of fat, it might be a good choice, but in my case I know I'll just have to do implants and I wanted to bring it up in case some people didn't know this and it will help in decision making.
0 -
congrats. piper, on the weight loss -- woo hoo! Have you noticed a decrease in your waist? Also, have you cut out fruits as part of your sugar avoidance?
I ask because I recently started tracking my intake with Weight Watchers. I have been eating lots of fiber (whole grain organic shredded wheat -- 0g sugar; beans; lentils; quinoa; and of course vegetables). I am avoiding sugar, but I do eat fruit. A half of a banana with my morning cereal; berries with plain Greek yogurt; and I snack on an orange and either apple or pear. So I'm eating about four fruit servings per day, but none seem too sweet or sugary. I'm down five pounds in two weeks -- it's the quick initial loss, and I don't expect it will continue at this rate (but wouldn't that be nice!). I also took measurements when I started, in case the scale stops moving -- I know this can happen while inches still come off, and that's really the most important thing, right?
Interesting what you said about DIEP -- I've wondered if the transplanted belly fat is still estrogen-producing.
0 -
Pipers, don't beat yourself up about the belly fat. I was 98% ER/PR positive and I had very little belly fat. I am thin, a non-smoker, and tested negative for genetics. And yet I still got cancer in both breasts, found at the same time. HOWEVER... I DO love my sugar. I did really well cutting out the sugar for about six months, but now I keep having my weak moments and have binges - and then feel sick! That book sounds interesting. I'll have to take a look at both books mentioned.
The latest thing that I need to figure out... my estrogen levels are now low, which I attribute to a hysterectomy (2 months before the cancer was found - but I kept my ovaries) and all the supplements including Curcumin and CDG DIM. I'm not taking tamoxifen, and I feel great. No hot flashes or other menopause symptoms. I'm 46. SO... is it GOOD that my estrogen levels are low or is it bad? I've read a little of Suzanne Somers and I'm wondering if in the long run I need to do hormonal replacement therapy? I know she does it and recommends it even for women who've had cancer.
Aargghhh.. there's always something to figure out!
0 -
gemini: I have def lost inches around my waist--more than I ever have before. Not eating much fruit except for some berries, but I'm doing ketogenic until I lose 12 more lbs and then will switch to a lower carb diet with complex carbs as a main focus. I now weigh less than I did since I had my first child over 22 years ago! And yes, the transplanted belly fat is still estrogen producing--it still has all the health effects of belly fat except that it looks prettier up there. What irritates me is that they were not going to tell me that and the PS surgeon told me not to lose weight! It seemed like such a perfect win-win scenario too.
klanders: not beating myself up so much as using this for a learning experience. I've had a potbelly since I was 8--wasn't really overweight then except a little belly fat and have been a sugar junkie as long as I can remember. In many ways I'm seeing that it's every bit as harmful as drugs, alcohol, and cigarettes. I can't reply to whether it's good or bad to have low estrogen at your age, but I know the breastcancerchoices.org website has some studies posted about HRT and BC--I don't know if you've seen those yet. Also, I'm thinking if you would take it, they would have you on tamox, which would lower it as far as it can go, right? It seems to me, and I'm just talking out of ignorance of all the facts though, that it would be better to have some estrogen, as long as it's balanced in the correct ratio, which is what DIM is supposed to do. If no menopause symptoms, then you're probably fine.
Which brings me to--I am also reading another book called Healing Fibroids: a Doctor's Guide to a Natural Cure. This book explains about all the hormone imbalance stuff and I'm just getting started, but it seems to me that much of the same advice that is given in it will help with curing BC naturally as well. Fibroids are a bear to treat, esp naturally, so most docs just want to do surgery, and as we know, BC is no piece of cake either. So, this is just a surmise on my part since the book is not about BC, though it is mentioned frequently, but my guess is that if hormones are unbalanced as I know mine are, then this is the approach for me to take. Others may have other routes that would be better for their case. Guess I'd better mention that I do suffer from fibroids as well, which is why I've hit almost 55 and still no menopause, though at least I've gotten irregular. I esp like the guided meditation section in the book--it's starting to sound do-able. I've been making my changes one at a time as I feel that it's getting to be a priority and meditation probably is next for me to take on. Anyway, it's a fantastic book for anyone who suspects hormonal imbalance may be a big part of the problem--just know that it takes awhile to turn that train around.
0 -
Hi, Klanders , Pipers, I was 95% ER/PR positive and I had very little belly fat. I am like you , a non-smoker, and tested negative for genetics. And yet I still got cancer in both breasts, found at the same time. I DONT love sugar, but take honey or brown sugar with my tea or coffee. I never found someone similar to my DX also i refused to take Tamoxifen - I take a look at both books mentioned, but i have to say i lost interest in food all together. I eat beans, quinoa, couscous, organic vegetables and i buy fruits but most times end up bad. i also like the whole grain bread. I just havent figure out the estrogen levels, what is the level we are to have? what is a low level ora high level? sorry i may have to google it. I am 41 now and i never had kids. BC came at 38 and i guess i may never have kids which is ok now. I was upset about it but now i am ok with that. Last month i started to wonder about this estrogen levels due to a few people been worry about me and asking me to come to this tread. Anyway thanks for sharing the info. I will search and see what was my level last time i check my blood.
0 -
Pipers, that's so great you're losing inches around your waist! Even though Weight Watchers doesn't forbid any food, I'm naturally gravitating to lower carb/low-glycemic foods. I have a hearty appetite and like to eat larger portions, so beans and veg are satisfyingly filling. I've been following the plan for two weeks now and feel so much better -- increase in energy, better mood. I imagine this is the result of a stable blood sugar level. I was eating way too much crap prior (things like tortilla chips and other refined carbs) to making this diet change. I'm tall and have been able to "carry" extra weight, which has made me dangerously complacent. In the past ten years I've gained 30 lbs, and a good bit of it is in the belly. I turn 50 this year, and I don't want to start this new decade behind the eight ball.
I know that women with low body fat can and do still get breast cancer. However, going forward, I feel that losing this extra weight and exercising is an important part of staving off a recurrence. I know I'll certainly feel better! :-)
Seven of the 30 pounds gained came on in the past year. While it is tempting for me to blame tamoxifen, i know the real source of the gain is crappy food choices and inactivity (and the crappy food zaps my energy so I don't feel like exercise -- a vicious circle!). I am pretty pleased with my weight loss so far, so i know that for me it is definitely possible to lose weight while on tamoxifen.
Keep up the good work, Pipers -- you must feel great!
0 -
I just want to clear up something that may have been misunderstood in my posts. I don't want to give the impression that I think that ER+/PR+ BC is caused by belly fat. There are as many reasons we get this as there are women but I'm unconvinced that genetics are the main reason b/c BC has gotten much more common than it used to be. What I am saying is that if you have a good amount of belly fat as I do (did!) and are HR+, you might want to consider that as a big part of something that needs to be taken care of, since belly fat is inflammatory to the system and produces estrogen and converts it to the bad kind--16 hydroxy-estrone. Oh hey, I just found an article written by Ori and it will explain most of what I'm trying to say. Excess estrogen and weight gain Anyway, I see no reason to beat myself up over it--what's done is done and I must move forward and many women have belly fat but don't get BC.
Another thing I have learned is that once you start putting on weight, it becomes a vicious cycle b/c the fat pumps out hormones that stay too long in your system and the hormones cause you to gain weight and feel like crap so you don't want to exercise. But yeah, on this low carb diet I've almost lost desire for food--must remind myself to eat now, and I do love that freedom. So gemini: congrats on your weight loss too--I think you'll find you're much more motivated this time around! And yah, I feel great, though the chelation therapy can drag my spirits thru the mud sometimes.
0 -
pipers, I didn't think you were implying that belly fat causes BC. However, it's a really good idea for us who have excess belly fat to do our best to reduce it as best we can. I can post articles, but if you do a quick google search of "dangerous waist measurement," you'll find some interesting reading. Apparently the danger zone for women is above 35" (which is where I was two weeks ago). Ideally it would be under 31" ... Much of the reading points to risks beyond BC, namely heart disease and diabetes.
I've also been doing some reading on high-fiber diet and estrogen. (Just googling that phrase.). I had heard something about this before, and Momine had mentioned a connection as well. It seems a high-fiber diet is quite efficient at sweeping away excess estrogen and eliminating it through waste. Pretty cool! I even found some articles about how some younger women on a high-fiber diet were having trouble conceiving because they had lower estrogen levels as a result of their diet.
Just like the little ditty from childhood ... "Beans, beans, the magical fruit!" Indeed!
0 -
I have been lurking here for a few weeks. You ladies are an amazing bunch....a huge source of information. I do my own research, but a big thank you for helping me figure out how to treat BC without chemicals.
I am prompted to post in reply to the belly fat issue. I never NEVER had a thick mid section. Ever...lol Now I do, barely a waist line at all. I started noticing I was losing my shape about 6 months to 8 months before dx. It was a small but steady incline if you will. I had my BMX in mid January 2014. I quit smoking 8 weeks ago (yay for me) and now have gained 9 lbs in a month. WTH. I do not over eat, I do not eat sugary stuff. Food is not my comfort thing. Today I saw my BS. She is not concerned about my weight gain. I am...Is it really because I quit smoking? I guess I'll google it. I want the belly gone! ASAP. Yes, I have read that estrogen is produced by fat. gotta get it gone.
I can't but think the cancer has been working its "magic" for quite sometime. It is so strange, I went through menopause 10 years ago, I am 58. Now, after having all this breast tissue removed I am having hot flashes again? don't get that either.
I am taking DIM, calcium with magnesium and zinc, D3, grape seed, garlic, olive leaf, and a ton of probiotics. I make everything from scratch and try to buy my groceries with as little as possible additives. I eat yogurt for breakfast and lunch.
I want my energy back and my flat skinny mid section back. Ahhhhhh! Oh and my skin on my face and chest and back is blotchy, red and itchy. I came out of the OR like that.......The probiotics has helped that a bit...but it is still yukky.
My BS gave me the name, at my request, of a Naturopath who is also an MD...I will see him asap.
This is a pain in the neck as I am sure you all know. So sorry for whining..
Thanks for listening
Eve
0 -
momaton, Congrats & YEEHA for quitting smoking...
I enjoy & lurk on this thread also, learning from everyone else. Thanks to all...
0 -
Holeinone,
LOL....do you dance by the light of the moon ?
I am assuming the YEEHA is from "It's a wonderful life?"
0 -
I just bought my first bottle of DIM. Yay! it says take 2 a day, is that what everyone else is doing? its DIM-Plus. It has the I3C in it. How does it make you feel, any side effects, what about doing 'number2'. Does it make you go to bathroom more? I just got to where I am only having about 3 or 4 hot flashes a day, that's going from 1 every hour (almost). Also no night sweats! Yay! any info will help. Love y'all ladies for all your info and support
0 -
What is DIM? You guys know it is taking me forever to be as wise as all of you!
0 -
I just read the full description and it says for intensive use double the dose. Is anyone else taking more than 2 a day
0 -
Hi Kathie
I am taking one a day. I see my naturopath on the 10th so I will find out more info then. I know she recommends taking it....so we'll see.
0 -
Momaton: one of the privileges of being on here is you get to whine all you want. LOL, I didn't think you were too whiny. Interesting observation that your belly fat increased, I'm assuming after your BC started. Could be a clue.
0 -
.0
-
Hi
LadiesI too
have been lurking! To write answers to all of the above I would say this:I do
not consume anydairyproducts
at all on advice from cancer DrI do
not consume anysugarin any
form, i.e. no fruit & no honey on advice from cancer DrYou can
consumeXylitolwith no
probs instead of sugar. It is a Carbon 5 as opposed to a Carbon 6 and as
such the cancer cells do not have receptors for Carbon 5I take
twoDIMper day - I think I wrote in detail the one
I take in an earlier post - check it out - it's a USA one anyway :-)Belly
fat arrives as one gets older/start the menopause it's because as the hormones
leave our bodies we put on fat where men do.I would
not go anywhere nearHRT- many connections with that and BCYes
it's good to keep your oestrogen down if you have BCA
fantastic CAM website is thecanceractive.comwebsite run by Chris Woollams - he has the
answer to just about everythingHope
this helps
0 -
Hi Ladies
I too have been lurking! To write answers to all of the above I would say this:
I do not consume any dairy products at all on advice from cancer Dr
I do not consume any sugar in any form, i.e. no fruit & no honey on advice from cancer Dr
You can consume Xylitol with no probs instead of sugar. It is a Carbon 5 as opposed to a Carbon 6 and as such the cancer cells do not have receptors for Carbon 5
I take two DIM per day - I think I wrote in detail the one I take in an earlier post - check it out - it's a USA one anyway :-)
Belly fat arrives as one gets older/start the menopause it's because as the hormones leave our bodies we put on fat where men do.
I would not go anywhere near HRT - many connections with that and BC
Yes it's good to keep your oestrogen down if you have BC
A fantastic CAM website is the canceractive.com website run by Chris Woollams - he has the answer to just about everything
Hope this helps
0 -
pipers,
yes I think my fatty belly started when the cancer started to become big enough to make my cancer boob become, how should I say this...apparent, bigger, in a way, different....just different. I actually had 5 small invasive tumors and the 1cm bigger tumor. SUPRISE!!!
I have read as many of the San Antonio bc stuff I could find...I am not encouraged about the effectiveness of AI's...no how no way.
My disbelief in the medical community comes from having been a caregiver to my former husband. dx with colon cancer...doing chemo..all clear for 2 months and then BAMB! brain tumor....18 months and then dead. Many, many promises of we can fix this....lol....we knew better...and the docs involved also knew better....sheesh....just tell me the dang truth will ya!
so here I sit. I don't think I will die from BC. I don't live like that. I just want some concrete answers. I want to do the best I can do right now for me. I want those answers and I do not think more chemicals will keep those little stem cells from creating more havoc. I want to be healthy and learn everything I can to make the best decisions for ME going forward. I still want my filet mingon(sp) and red wine on occasion. Like my BS said your chances of getting bc back is either 0% or 100%.
thanks all for posting and being smart and willing to share....
love to all,
Eve
0 -
DIM? lol
0 -
Well, at least I got a LOL. Thanks
0 -
- Breakthrough Discovery at UC Berkeley: Diindolylmethane (DIM) is a Powerful Natural Immune System Booster
lostboob-
Breakthrough Discovery at UC Berkeley: Diindolylmethane (DIM) is a Powerful Natural Immune System Booster
Diindolylmethane (DIM) Natural Immune System Booster
Search this site0 -
Thank you Salina. I never felt more stupid than I did on this one. I'm definitely in the wrong forum but your explanation helps and I can pass it along to those that might not know.
0 -
lostboob- no worries, I pretty much find everything by googling it!
0 -
Thanks Salina, i actually did the same lol google also went back and read a few of the previous pages here and someone had given a link. I am glad i came here i will go find this DIM, tomorrow, i hope i find it at a health store.
Thanks again
0