Kisqali (ribociclib)

Hair loss and Kisqali
I have been recently diagnosed with Stage IV metastatic breast cancer after a year being stage II. I started Kisqali last week and was told I would only have hair thinning. I am loosing chunks of hair. Would love to hear if anyone has experienced this? My oncologist told me none of her patients had to get wigs and only had…
Kisqali/ribociclib, Faslodex/fluvestrant & Xgeva combo - Anyone?
I've been on this combo since Nov 2019. Since all treatment combos seem to offer their own side effects and challenges, I'd like to hear from others taking these drugs. Especially your experiences, duration of success and how you deal with the fatigue, itchiness, etc that goes along with this treatment.
Ribociclib/Kisqali with Letrozole - Any one on this combo?
I am starting this new forum for all those who are on this newly approved drug combo. I started on Kisqali/Letrozole combo 6 weeks ago and so far it has been tolerable. Letrozole gives me joint pain and low back pain. My oncologist has asked me to take this on alternate days. Would love to hear from others about their…
Kisqali side effects
hi I have stage 2 invasive lobular breast cancer; have had 2 surgeries & radiation Now have started arimidex & kisqali. I have flu symptoms usually everyday with low grade fever & body aches. Has anyone else felt like this & how long does it last
FDA Approves Kisqali for Early-Stage Breast Cancer
FDA Approves Kisqali for Early-Stage Breast Cancer September 17, 2024 Kisqali (chemical name: ribociclib) can now be used after surgery in combination with an aromatase inhibitor to treat stage II or stage III hormone receptor-positive, HER2-negative breast cancer with a high risk of recurrence. Read more…
Kisqali side effects and timing
I was diagnosed with stage four NBC earlier this year and just started a combination of anastrozole and Kisqali. I am three weeks on with one week off. I have experienced some persistent nausea, but most concerning is my serious fatigue. I’m wondering if this improves over the months as you continue with the Kisqali? I’m…
Feeling like an Imposter
Six years ago, at age 46, I was diagnosed with Stage 1B mixed mammary carcinoma, ER+/PR+, HER2- in one breast. I had one surgery - double mastectomy plus bilateral salping-oophorectomy direct to reconstruction. I have a strong family history of breast and ovarian cancer. I did not need radiation and my Oncotype score of 18…
Just diagnosed with ILC mets
Hi, all I had ILC back in 2008. Had radical mastectomy on the right breast and prophylactic on the left. Chemo AC→T, radiation and 7 years of Arimidex. 16 years later I am back in the game. Still in discovery phase. Had FDG Pet Scan that shows liver uptake, had endoscopy that shows little spot in the stomach consistent…
Important Stage IV Topics and Links for Stage IV Newbies
Here are some helpful resources if you've just been diagnosed with stage IV breast cancer, also known as metastatic or MBC. Join our free Virtual Support Groups for MBC! All with Metastatic Breast Cancer (MBC; also called stage IV) Register: Mondays at 2:00 PM EST, Tuesdays at 8:30 PM EST and Wednesdays at 4:00 PM EST…
Early Stage Breast Cancer - anyone on Letrozole and Ribociclib?
Wondering if anyone has been diagnosed with Early Stage Breast Cancer and on AI/Ribociclib regimen? I’m going to start after radiation and wondering how your treatment is going and if there are any tips out there! Thanks in advance!
Multiple Organ Mets and on Kisqali/Ribociclib (3+yrs)
I always hear amazing stories from those with dx’d with bone mets de novo on this drug. Curious to hear from those with multiple organ mets or were dx’d secondary who have done well long term on the Kisqali/Ribociclib combo. Where were your mets, and how long have you been on this treatment?
What to expect from Kisqali (side effects)?
Hi, I'm a caregiver to my mom, who was diagnosed de novo with metastatic breast cancer just last month in August 2024. She has metastases to the bones, liver, and lungs, and she's scheduled for a brain MRI next week. She's started on Letrozole, which was paused while she's been undergoing palliative radiation therapy to…
CDK4/6 inhibitors
If you have taken Ibrance or Kisqali or another CDK 4/6 inhibitor, I would appreciate hearing about your experience. I recently had to stop Verzenio because of unmanageable side effects. Oncologist wants me to consider an alternative in that drug class.
Anyone on Kisqali and Exemestane? SE?
Hi, all I switched to Exemestane from Letrazole due to unbearable rash with the Kisqali/Letrozole combo. But on Exemestane the skin on my palms and feet is scaling, peeling off. Any advice? Also my hair is thining. What SE do you have and how do you deal with them? Thanks
NATALEE TRIAL
My dr. wants me to join the Natalee trial which is based on the success of the Monaleesa trial for women with Stage 4 breast cancer. the drug is Kisqali (ribociclib) tablets. It was administered in 6 mg tablets for the Monaleesa trial and will be given in 4 mg for the Natalee trial. The problem I am having with it is the…
Kisqali
Anyone taking Kisqali for Advanced Stage Metastatic Cancer. If so how how long did it take for you to know if it was working for you? I have Mets to my liver and spine, likely in lungs too. I just want to feel better.
Not responding to Verzenio after some months: anyone switch to Kisquali? Help please
Hi all My tumor markers dropped for the first few months on Verzenio/Fulvestrant, and now are climbing again. Scans didn't show progress last month but I'm terrified. Did anyone have better response switching to Kisquali and if so, what was it and how were the side effects compared to Verzenio? Verzenio and I are getting…
Help regarding kisqali medication
I have an aunt suffering from breast cancer, which discovered recently , the doctor prescribed her a medicine called kisqali, the problem is the price of this medicine is very high, about 3000 dollars here in Morocco , and the financial situation of the family is very difficult, my question is Are there associations that…
Beginning Targeted Therapy? Start here.
Please start a new post/discussion for a targeted therapy that you'd like to discuss, if you don't see it here already, so others can join in with their experiences. Note: If you are Stage IV (metastatic), there are many threads addressing these medications for Stage IV patients in the Stage IV forum you may find helpful.…
I am lost and scared that my next option is chemo. Emotional Yo-Yo and I have chemo PTSD
Hi there i just need to vent my fears. Not even 2 years with MBC and i am about to quit all treatments. Emotional Yo-Yo takes tall. Back in 2016 chemos were rough but i was going for the win. But this time around is different. There is no end of treatment and there is no win per se. I am lost and scared that my next option…
Kisqali side effects
Hello.. I am on week 3 of the first cycle of Kisqali. I have had the dosage lowered to 400 due to gastrointestinal side effects. The stomach cramps are terrible. I have tried dycyclamine, mylanta, gas x, pepto, and other over the counter and nothing helps. I also use a low setting heating pad which does help. I do have…
How long on a CDK 4/6 inhibitor (Ibrance/verzenio/Kisqali)?
I’m sure this info is buried deep in the various stage iv threads, but I’m hoping people will post their experiences and success stories here. I think the median from the initial studies was about 2 years, but obviously there is more real world experience as time passes. Thank you!
Treatment After CDK4/6 Inhibitors
Treatment After CDK4/6 Inhibitors Dec 5, 2023 Medical oncologist Stephanie Graff explains the treatment options available after a CDK4/6 inhibitor stops working. CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer. The CDK4/6 inhibitors are: Ibrance…
Diagnosed with MBC!
10 years ago, I was diagnosed with breast cancer. I had a lumpectomy, chemo, a mastectomy, radiation and reconstruction. In April of this year I was diagnosed with MBC. I am on Kisqali. After initial side effects, I have adjusted to the meds and have been asymptomatic. Physically I am doing okay. Emotionally I am a roller…
joint replacement while on Ribociclib
I have bone on bone osteoarthritis in my L shoulder which also is the side of my initial breast surgery and radiation in 2018. Currently I am on Ribociclib and Faslodex for recent mets to liver. My ortho is recommending joint replacement. Has anyone had a joint replaced while on these meds? Thanks,
Progression after ribociclib (csk4/6i) and letrozole
Hi I had her2 neg er+ breast cancer in 2018. In 2022 i had recurrence in my bones (all over with 3 collapsed vertebrae) and liver. I was on ribociclib and letrozole that worked really well, pet was negative and most metastasis disappear. In August I had liver recurrence. Blood test and markers are ok and i feel well so i…
Progression after ribociclib (or cdk4/6) and letrozole
Hi I had her2 neg er+ breast cancer in 2018. In 2022 i had recurrence in my bones (all over with 3 collapsed vertebrae) and liver. I was on ribociclib and letrozole that worked really well, pet was negative and most metastasis disappear. In August I had liver recurrence. Blood test and markers are ok and i feel well so i…
Kisqali Plus Hormonal Therapy After Surgery for Early-Stage Breast Cancer Reduces Recurrence Risk
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Kisqali (ribociclib)

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