Ringworm drug for dogs (Fenbendazole) might also cure cancer
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Saulius, great family, thank you for sharing
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Great pictures, thanks for posting them. I'm afraid I am under strict confidentiality here. My wife and I worry that if the oncologist somehow was able to find out what all we do, we would have problems.
I am searching pubmed and other sources for repurposed drugs for use against cancer. I found an interesting drug that is an anti-viral, called ribavirin:
https://www.ncbi.nlm.nih.gov/pubmed/31263027
Abstract
The growing cost of medical care worldwide, particularly in oncology, has incentivized researchers and physicians to repurpose clinically used drugs to alleviate the financial burden of drug development and offer potential new therapeutics. Recent works have demonstrated anticancer properties of the FDA-approved drug ribavirin, a synthetic guanosine analogue and antiviral molecule used over the past four decades for the treatment of hepatitis C. The efficacy of ribavirin in cancer has been explored through several preclinical models and ongoing clinical trials in multiple cancers, including acute myeloid leukemia, oropharyngeal squamous cell carcinoma, and metastatic breast cancer. In this review, we summarize the role of ribavirin as an antiviral medication and focus our attention on its recent use as an antitumoral agent. We highlight current knowledge of the potential use and mechanisms of action of ribavirin in cancer. Because current therapeutics for patients with cancer still fail to cure, introducing new forms of treatment is essential. Converging evidence suggests that ribavirin represents a promising addition to a generation of newly repurposed safe and effective anticancer agents.
And when search ribavirin for breast cancer, found another drug combo specific for breast cancer called ABC7 designed to enhance xeloda / capecitabine:
Abstract
Breast cancer metastatic to bone has a poor prognosis despite recent advances in our understanding of the biology of both bone and breast cancer. This article presents a new approach, the ABC7 regimen (Adjuvant for Breast Cancer treatment using seven repurposed drugs), to metastatic breast cancer. ABC7 aims to defeat aspects of epithelial-to-mesenchymal transition (EMT) that lead to dissemination of breast cancer to bone. As add-on to current standard treatment with capecitabine, ABC7 uses ancillary attributes of seven already-marketed noncancer treatment drugs to stop both the natural EMT process inherent to breast cancer and the added EMT occurring as a response to current treatment modalities. Chemotherapy, radiation, and surgery provoke EMT in cancer generally and in breast cancer specifically. ABC7 uses standard doses of capecitabine as used in treating breast cancer today. In addition, ABC7 uses 1) an older psychiatric drug, quetiapine, to block RANK signaling; 2) pirfenidone, an anti-fibrosis drug to block TGF-beta signaling; 3) rifabutin, an antibiotic to block beta-catenin signaling; 4) metformin, a first-line antidiabetic drug to stimulate AMPK and inhibit mammalian target of rapamycin, (mTOR); 5) propranolol, a beta-blocker to block beta-adrenergic signaling; 6) agomelatine, a melatonergic antidepressant to stimulate M1 and M2 melatonergic receptors; and 7) ribavirin, an antiviral drug to prevent eIF4E phosphorylation. All these block the signaling pathways - RANK, TGF-beta, mTOR, beta-adrenergic receptors, and phosphorylated eIF4E - that have been shown to trigger EMT and enhance breast cancer growth and so are worthwhile targets to inhibit. Agonism at MT1 and MT2 melatonergic receptors has been shown to inhibit both breast cancer EMT and growth. This ensemble was designed to be safe and augment capecitabine efficacy. Given the expected outcome of metastatic breast cancer as it stands today, ABC7 warrants a cautious trial.
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Saulius,
I tried asking on the Mycancerstoryrocks facebook group about what drugs Joe Tippens was on during his initial use of fenbendazole. Posts must all pass by the admins. The admins declined to allow my post, but replied to me personally saying keytruda. So all we know is that he was on keytruda, fenbendazole and his other supplements. Not sure if the keytruda was combined with anything else in the clinical trial.
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Great pics! Here is a pic of me and my DH.
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My Son and his family
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I believe Perrier is also owned by nestle... I drink a lot of water in plastic bottles mostly soda water but it is always spring water bc like I mentioned above purified water bothers my bladder..thats also why I am worried about getting the filter..to pay all that money and then if it bothers my bladder anyway...but we may just go for it.
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And this is a rare photo of all 3 grandsons smiling
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Simone..wow I cannot believe that is your son!!! You do not look old enough to be his mom.
Cute boys...3 wow he's got his hands full for sure 
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Husband wow thanks for that!!! Well I am wondering now and hoping that the ribavirin in particular would be safe for liver because it says it was used in the treatment of Hep C!!!!! wow I think I may send your post to my MO....she turned me down for Hydroxchloriquine> spelling b/c of how taxing to the liver it can be...
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Thanks Nicole. Yes, they are a handful. I'm not sure how they do it.
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My heart is filled with joy and happiness, seeing all of these beautiful people. From the bottom of my heart, thank you all for sharing!
Saulius, those smiles! So full of love and happiness. Sandra is beautiful and that is a picture of love, the way Vijus is looking at his mommy. Beautiful family. Like Olma said, Vijus has a very angelic face, and your smile is contagious!
Simone, what a beautful couple. Where is the pic taken of you and your husband? Handsome son and those grand babies...I so wish I had some. They couldn't be any cuter and they are at such a fun age. Same with Saulius's little one.
Olma, thank for the compliments on my hair. They alwasy say us older women should wear short hair, I just can't! I like my long hair, makes me feel like 40 instead 61. But 60 is the new 40, right! I too try to avoid plastic and NEVER heat anything up in the micro wave in plastic, IF I even use the micro wave. My husband heats everything in plastic!
Husband, I totally understand. Privacy is important.
Blessings to all of you and may we all get through this! Wishing you all a Happy Halloween!
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Hi Goldie,
thank you. We were in the Superstition Mountains overlooking Canyon lake in Apache Junction. My brother and sister in law were in town last week. There is a steam boat called the Dolly that we like to take visitors on. It is so beautiful there.
You have such beautiful hair. I have always had fine hair so I've always kept it short.
Re plastic: I have been converting over to glass also and getting rid of the plastic containers. We have reverse osmosis and I'll fill my yeti when we head out in the car. I haven't found a good replacement for water bottles yet. I hike a lot and the plastic bottles are convenient and lightweight. Any suggestions?
Happy Halloween 🎃
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Thank you Simone. Have not heard of that boat tour. Will have to look into that. I have a BPA free (I think that's what it's called) glass that I use, it also has a pink ribbon on it. Gift from my brother in my photo. I have 2 other brothers as well. There are other cups, out there. I think there is one called a yeti, keeps stuff cold for like over 24 hours, but expensive. Also metal ones.
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Mike--I agree with the others you need a new oncologist. Nothing is over until God says its over. Here is a link to a great sermon on that topic: https://www.sermoncentral.com/sermons/its-not-over-until-god-says-its-over-john-wilkinson-sermon-on-love-232661
My husband would love the car and would spend hours talking about it with you. . You sound like a wonderful caretaker, along with Saulius--and that is definitely the hardest job in the world I think. All of you--Mike and your wife, Saulius and Sandra, along with EVERYONE ELSE on this thread are in my prayers.
As far as water goes I heard the Big Berkey is best at filtering everything bad in our water. . . including hormones we are all getting from many various sources that many of us with estrogen driven cancers should not be getting: https://www.berkeyfilters.com/collections/berkey-water-filter-systems/products/big-berkey?a_aid=538a5cb8c8907&a_bid=8b4878fc. I learned of it from this guy's book: https://www.biohackerslab.com/ep51-dr-anthony-jay/
Goldie, loved seeing all the pics of everyone. It was a great idea. And love your long hair. You can see I am also a long hair kind of gal. Happy Halloween--hope it is all treats and no tricks for everyone!
Some pics of my family:
My son (who was as big as Vijus it feels like just yesterday!), me and my husband.
My son and I
My son, my niece, me and my husband
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mysticalcity,
Nice pics. It's so nice to see faces to the names.
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Good morning everyone. What a night I had. First, let me say, when I go to bed it takes me a long time to fall asleep, no matter how tired and taking 20mg of Melatonin. I went to bed at 8pm and the last time I saw on the clock was 11pm! My brain will just not shut off! Last night I laid in bed thinking of all you and the pictures that were shared. Tears running down my face that just wouldn't stop. Tears of joy and tears of sadness, not crying, just tears. And Sauluis, your sweet babies face was there the most. This morning I woke up with the same, thinking of all of you and more tears. Thank you all for blessing my life and sharing yours with us.
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What's with Amazon, I'm restricted by the manufacturer to one purchase of Panacure only? Has this happened before? Are they getting ready to limit purchase to prescription only?
Wife is actually doing a bit better. Had a visit from a physical therapy palliative care guy and he showed me some tips about her wheel chair I didn't know. Without the leg attachments I can wheel her all around much better than the walker. Her usual late night bathroom disaster wasn't so bad.
I finally bought an antique car. It's a pure white 1957 T-Bird with port holes. I really needed something to take my mind off the constant job of care giver. The car, from pictures anyway, looks perfect. I swear somebody had a time machine and went back to 1957 and brought it back with them. Just 37,000 miles (if that is to be believed).
One little parting shot from my wife's MO. Even if she got better he still wouldn't give her anymore chemo due to her nephropathy. He was a nice guy until my wife's health went south. I think he's one of those compartment people. Life is simple, just compartmentalize everybody into neat little boxes.
Sorry from the long rant; things get boring around the house. Yea right, 500 Xfinity channel but not much on any of them.
Call me "T-Bird Mike" from now on please.
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To my horror, I'm confirming Mike's finding, not only we can no longer buy multiple boxes of Panacur-C, but the prices have skyrocketed...I had suspected this would happen..they are cracking down...soon we will need a hard to get prescription...
Mike, may your wife experience a healing, like Joe did, and prove the mo wrong...may you enjoy your new expensive and i'm sure beautiful toy....
Thank you everyone for posting your beautiful family photos, it will be a real pleasure, from now on, to see your face when I read your posts.
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"may you enjoy your new expensive and i'm sure beautiful toy" Yes it is a toy and I feel bad about that.
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I just checked our Canadian source and they just got restock, and we ordered 10 of the 4.5 gram packets plus some ivermectin, but I see they have now noted on their website that they will be limiting order sizes to 100 packets. I do see they still have the 454 gram packages for $333 cdn.
I am worried that maybe we should order more.
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Mike I didn't mean for you to feel bad...enjoy the car...We all need to enjoy as much as possible to stay sane, all considered...
My gut says...stock while you can...the AMA has blocked every other effective cancer therapy and they are not going to stop now...
We can always use the COC prescription for the MB but I'm not sure it would be as effective...
Based on the COC, I'm switching to the doxy this month...I'm glad to save the panacur-c in view of what's going on...
What kind of world we live in, where people and doctors have no qualms abusing the most needy, weak and vulnerable...the good news is: what goes around, comes around...
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Just a quick note on water bottles - I bought a couple of glass ones like this one, it has a silicone sleeve to prevent breakage. Yes, they are a little bit heavier than a bottle of poland spring but not too bad. Search "glass water bottle" for other designs.
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I can see in the near future your walking down a dark rubbish strewn alley in a bad part of town. Graffiti on all the dirty alley walls. Some guy come out of the shadows. "I need some Ben, got any?" you ask. Yea," replies the thug, "but it's gon'na cost ya." The AMA might cause this very scenario to happen.
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Thanks Olma. I'll give it a try.
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https://www.1800petmeds.com/Panacur+C+Canine+Dewor...
Still available at pet meds at old price and in quantity...but out of stock currently...
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Great article on melatonin someone on my Facebook Repurposed Drugs page posted yesterday:
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Mysticalcity, thanks for posting that article.
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Yes, great article on Melatonin! Question for those who use high doses - I currently take 5mg at night for sleep. If you are taking 20 or more mg does it effect your sleep and does it make you drowsy during the day? The 5mg does not make me drowsy or hard to awaken in the AM but I'm afraid to take more...
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I'm doing 20mg.at night that I take with magnesium, but not a super high dose yet of melatonin (some do as high as 180mg). I do think I sleep deeper than when I don't use it and seems like I sometimes have some weird or vivid dreams, but I don't have problems waking up or feeling drowsy during the day at all. In fact because I sleep more deeply I usually feel more rested than I do without it. I would work your way up though, by adding 5mg or so at a time, as I read that you can get headaches if you up it too quickly.
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Olma, I've been taking between 20 and 30mg before going to bed and I'm not drowsy in the morning, unless I wake up around three or four am anyway, and fall asleep again around 5, then I’m kind of drowsy around 8-9 am
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