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Finishing AC and starting T
I just finished my last infusion of AC and in two weeks will start Taxol. My doctor originally told me 1 infusion of Taxol per week for 12 weeks but during our last appointment he recommended I do 8 weeks of Taxol with an infusion every 2 weeks so a more dose-dense treatment. He recommended that because I tolerated the AC…
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Lymph node removed but pathology says no evidence of lymphatic tissue found!
Has anybody had masectomy with sentinel lymph node removed but pathology says no lymphatic tissue found? I’m seeing breast surgeon tomorrow and oncologist next week. Will I need another procedure? I’m not sure I’m comfortable not having lymph node tested as this is my second time having breast cancer!
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Has anyone had a LOW oncotype with the ER + 100%, Pr- 0% and Her2-??
Oncotype results…. I am 38, pre menapausal, BRCA negative, no family history of breast cancer.
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Deciding on what type of reconstruction
I will be having a double mastectomy with immediate reconstruction on Nov 6 on Long Island,ny. My surgeon’s will be Dr Hodyl and Dr ott young. I have a new primary cancer on my right breast. Idc hr+her- (same as last time 10 years ago) I previously had lumpectomy and radiation and tamoxifen. My oncotype score was 10. I…
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Anyone 5+ years with liver mets and ER+ Her2-?
I just have to ask. If you had liver mets at diagnosis of mbc, and you are ER positive and Her2 negative, and have reached five years already, please raise your hand. Most of the 5+ years women I see here on BCO are either Her2+ (the Her2 drugs are quite successful), or they started with, and may still have, only bone…
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Second time around needing Chemo - just wondering about the prescribed treatment
Double mastectomy 7 years ago. New 1-2 cm cancerous lump found on breast and also in three sentinel nodes have all been removed. Same cancer (EST+, HER2- ). Having more surgery next week to remove 1st and 2nd level nodes. After surgery, my oncologist is prescribing Doxorubicin and Cyclophosphamide every two weeks for 4…
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Early Stage Breast Cancer - anyone on Letrozole and Ribociclib?
Wondering if anyone has been diagnosed with Early Stage Breast Cancer and on AI/Ribociclib regimen? I’m going to start after radiation and wondering how your treatment is going and if there are any tips out there! Thanks in advance!
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FDA Approves Kisqali for Early-Stage Breast Cancer
FDA Approves Kisqali for Early-Stage Breast Cancer September 17, 2024 Kisqali (chemical name: ribociclib) can now be used after surgery in combination with an aromatase inhibitor to treat stage II or stage III hormone receptor-positive, HER2-negative breast cancer with a high risk of recurrence. Read more…
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Testing for ESR1 Mutations, Then Switching to Camizestrant Improves Outcomes for HR+ HER2- MBC
Testing for ESR1 Mutations, Then Switching to Camizestrant Improves Outcomes for Metastatic HR+ HER2- Breast Cancer May 31, 2025 After two years of follow-up, the new treatment improved survival and quality of life. Read more…
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Met with my medical and surgical oncologists yesterday (99% ER+ 96% PR+ HER2-, prognostic stage 2A)
Long post incoming, sorry. Following up on my initial IDC diagnosis — ER+ (99%) PR+ (96%) HER2-. Grade 2 tumor. Premenopausal (40F). Prognostic stage 1B or 2A per the MO, but leaning 2A. One 1.9cm mass and at least one axillary node confirmed positive from biopsy (three additional nodes noted to be suspicious on initial…
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What should be my next step?
My biopsy confirms that I have Invasive Mammary Carcinoma in my right breast, which is hormone receptor-positive (HR+), HER2-negative, and a high Ki-67 proliferation rate of over 80%. Can someone tell me more about that Ki-67 number? Is it normal? Also the doctor initially said it was only one centimeter but the report…
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In Search of Holistic Treatment After Lumpectomy
Hello =) I am looking for like-minded people who would prefer to use holistic means rather than the traditional standard of care after surgery. What do you do? Intermittent fasting? Organic plant-based diet? No sugar/dairy? Quality supplements? Do you see a Functional Doctor for guidance? Do you get regular bloodwork work…
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FDA Approves Dato-DXd for advanced-stage HR+, HER2- breast cancer
https://www.breastcancer.org/treatment/targeted-therapy/dato-dxd
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Psychological reactions to aromatase inhibitors.
I'm sure this has been discussed on other pages but I want to start a thread specifically for this discussion. For the second time, I have had a severe neurological response to Aromatase inhibitors. The first time I was told there is nothing that would help so I quit taking the meds That was 6.5 years ago. I recently had a…
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Stage 1a to Stage 4 in 6 years. 39 yo. Mets to liver & bone. Chek2+
Hi everyone, my first dx was in 2018 (age 32) after self discovery. I had a Bi-lat mastectomy and had been on tamoxifen. Oncotype 11 so no chemo recommended. ER+/PR+. Chek2 positive. Feeling great with no symptoms, I did a Galleri test this October 2024, which came back with positive breast signal. CT scan w contrast…
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Osteoporosis
This is my first post here. I was diagnosed on 7/22 with left side IDC, E+P-HER2- and I'm having a lumpectomy next Wednesday 8/28. No genetic markers for cancer. I've had an MRI, the Savi Scout placed yesterday, the sentinel node injection next Tuesday. This morning I had a Dexascan and my surgeon called this afternoon and…
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Anastrozole for DCIS and colon cancer?
Hello, I am newly diagnosed with DCIS. Stage 0, Grade 2 and hormone positive. I am about to start my radiation journey soon and with the advise of my breast surgeon, see a medical oncologist after radiation to talk about hormone blockers. I am not a candidate for tamoxifen so it would most likely be Anastrozole (or…
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Primary endocrine resistance
hello. I was dx with stage IV de novo in July 2023. ER/PR+, Her2 - small Mets to pelvis Treatment was Letrozole with Ribociclib. First scan after 4 months showed reduction. Second scan 3 months later showed bone mets reduced but small spots on liver. Told I was primary endocrine resistant. Moved on to capacetabine. On…
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Oncotype Score
I recently had a lumpectomy for Stage 2 ILC which was ER/PR+ HER2-. Tumor was 29mm. There was a micrometasticts found in 1 of 3 lymph nodes. I am 41 years old. I received my Oncotype report today and am hoping others may be able to comment or share their story with similar results and what treatment they moved forward…
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Breast Cancer Index
I am near the 5-year mark of my endocrine therapy. I am meeting with my MO next month. She ordered the Breast Cancer Index test; the result is that I am not likely to benefit from extended endocrine therapy. Does it mean I do not have to continue with my monthly Lupron injection and letrozole beyond 5 years? How do…