Ringworm drug for dogs (Fenbendazole) might also cure cancer

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  • anotherone
    anotherone Member Posts: 555

    you sound certainly as every excited child :)

  • husband11
    husband11 Member Posts: 1,287

    Based on that video about taking 60 mg 3x a day, my wife is now popping 5 and 10 mg melatonin's throughout the day. It has not interfered with her sleep pattern, nor is it causing her daytime drowsiness. As well, she has recently started taking gabapentin, and it sleeping much more soundly than she did with sleeping pills.

  • husband11
    husband11 Member Posts: 1,287

    Just got back blood test results from my wife. Both tumor markers, although low, in the low teens, took a slight upward movement by a couple of points. One went from 11 to 13 and the other around 12 to 15. We are trying to stay calm and not panic. They have been that high, but that was over a year ago. Hopefully this isn't the beginning of a trend. We were hoping for better than average, as she has been on the fenbendazole and vit E for around 3-4 weeks prior to this latest blood test. Melatonin throughout the day as well. Next test isn't until November, so its a long wait. She also gets a bone scan then.

  • Frisky
    Frisky Member Posts: 1,686

    Husband what are you worried about? Mine are in the hundreds....I'm absolutely positive that couple points don't mean much...keep on doing what you're doing....your wife is in good hands.

    I just made a ginger tea with two teaspoons of powdered ginger I just bought from amazon. I added some almond milk and a few drops of stevia and OMG...it's so hot tasting...I'm sure it has all the gingerols and shogaols I need....I'm good to go! Delicious cancer therapy, if there ever was one

  • husband11
    husband11 Member Posts: 1,287

    Thanks Frisky. Enjoy the ginger, it sounds delicious.

  • moderators
    moderators Posts: 8,643

    Hi all, we thought you'd find our latest Podcast interesting:

    What My Patients Are Asking: Can Dog Deworming Medicine Treat Breast Cancer?

    August 30, 2019

    Brian wojciechowski md final 6340

    Brian Wojciechowski, M.D., practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and Lankenau Medical Center. Dr. Wojciechowski is a sought-after speaker on the topics of medical ethics and the biology of cancer.

    Blogs and popular media have discussed using fenbendazole (brand names: Panacure, Safe-Guard), a drug used to deworm dogs, to treat cancer. While some studies on cells in petri dishes and in mice suggest that fenbendazole might have anti-cancer properties, no studies have been done in people and it's not clear what side effects it may cause or what the optimal dose might be.

    Listen to the podcast to hear Dr. Wojciechowski talk about:

    • the type of drug fenbendazole is and how it might kill cancer cells
    • the studies in petri dishes and mice on fenbendazole that have been done so far
    • what he tells his patients when they ask about fenbendazole

    Running time: 14:58

    Listen now or read the transcript.

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    Thank you Mods. Very interesting podcast

  • anotherone
    anotherone Member Posts: 555

    re ginger - my taste buds have changed since diagnosis; I did not used to like it while now I genuinely do most of the time and I surprise myself what quantities I can tolerate - I still do not use much but compared to how it was it is like 10fold increase and could do more. I think hitting myself with near starvation in the first couple of weeks while having all the time ginger tea must have reset my taste buds. Shame I still like good quality cheesecake- that did not go away ! Baked carrot cake today , if it tastes good I will copy the recipe on the cooking board.

    Husband, one of COC participants said that it takes about 12 weeks to kick in. How does your wife feel generally ? What is her level of functioning?


  • cure-ious
    cure-ious Member Posts: 2,897

    It would have been interesting to ask him, given that fenbendazole works by inhibiting microtubules, as do taxols and relatied chemos (and he was clear in saying fenben preferentially hits the rapidly dividing cancer cells over normal cells, but is no different than other chemos in this respect- whereas targeted drugs like CDK4,6 or PI3K inhibitors are more selective for the cancer cell), then why does fenben not come with the awful side effects the other chemos do? And, given that, why would this compound not have been under more active investigation by pharma?

    FYI, in the literature it is reported fenben binds to microtubules at a different location than taxanes do, so that might be why there are not the standard SEs, also, they have now encapsulated a new-gen version of fenben into nanoparticles for testing in clinical trials, and the human drug (mebendazole) actually is being tested in two trials (altho not for breast cancer). But no reason apriori that he would know about any of these things.

    I also appreciated the background he provided about the mice assays and the platinum story- thanks, Mods!!!

    PS this type of podcast would be very helpful to cover areas that onclive and other sites are pretty much ignoring, for example how to best chose among various treatment options after Ibrance-Femara, how to gauge it when there are no biomarkers, or the cancer remains bone-only and there is no possibility for biopsy, what are the exciting immunotherapy combos and strategies entering clinical trials, is anybody looking at CAR-T for MBC, etc.

  • JFL
    JFL Member Posts: 1,373

    Mods, thanks for posting the information/podcast. I will definitely listen to it!


  • snooky1954
    snooky1954 Member Posts: 850

    I saw your concern for my well being. I'm fine. End of Zeloda cycle was very tiring.

    Meanwhile, chamomile tea anyone? Not only does it help with sleep, it's anti-cancer.

    https://www.ncbi.nlm.nih.gov/pubmed/30602390

    ------------------------

    I need time to review all the posts and then I'll be back!

    Heart


  • Frisky
    Frisky Member Posts: 1,686

    Snooky glad to hear your voice, and that you’re well...I Love to drink chamomile tea when I’m restless...it brings up tender memories of growing up in Italy where it was consumed regularly by young and old.

    Mods, Thank you for providing more information on the FZ....

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    Snooky, I'm glad to hear from you. I send you soft hugs❤

    Frisky, I can imagine how delicious and fragrant the chamomile of the Italian meadows is ...


  • mysticalcity
    mysticalcity Member Posts: 184

    All--with several posts discussing melatonin--again this might be a duplicate for you all--but this presentation on melatonin I thought had some great information that corrobated other studies I've seen about melatonin and cancer.

    https://riordanclinic.org/wp-content/uploads/2019/03/3-3-Shallenberger-High-Dose-Melatonin-Therapy-An-Ideal-Adjuvant.pdf

  • husband11
    husband11 Member Posts: 1,287

    Anotherone, my wife actually feels the best she probably has in years. Her energy levels are good. When we go for a walk, she walks as fast as she ever did. Which is an improvement. I take that as a reassuring sign that metabolically things are going well. Its just that it seems only once a year or less, her tumor markers take a jump upward. That of course destabilizes our already fragile sense of well being and confidence. I am welling to admit, I am quite emotionally fragile about her health. It doesn't take much to throw me off.

    Curious, I agree about the perhaps invalidity of lumping all similar therapeutics together, such as tubulin destabilizers. Subtle differences in structure can have immense impacts on action. Compare steroids - estrogen, testosterone, cholesterol and prednisone. All extremely similar in structure, yet exerting vastly different effects. Profit being a primary motive for investment by pharmaceutical companies, there is just not the incentive to invest in research into fenbendazole as there is something patented. Hopefully funding becomes available by some benevolent organization to shed more light on how to best benefit from fenbendazole.

    Having read more recently on the subject of melatonin, and also researched the possible negative drug interactions and risks, it seems more and more supported as a therapeutic for cancer patients, and in particular those with hormone dependent diseases like breast and prostate cancer. I have ordered a mg digital scale so I can measure the powdered melatonin that I plan to order from bulk supplements.

  • anotherone
    anotherone Member Posts: 555

    I remember we and in particularly my grandma used to drink it all the time. When I said it to my daughter she asked :"did you have teabags back then in the village?" ( I spend most of my childhood in a small remote Ukrainian village at the border with Moldova) to which I responded that we used to collect camomile herb, dry it off and use a few plants in a teapot :).

    Husband, Chris Woolams (www.canceractive.com) who I spoken today advised IVvitC after like 9 months of COC protocol ( I do not remember what was it that connected those two lodes of treatment) so to me it means to see results of COC properly it takes like 9 months.

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    Anotherone: Kids... LOL 😊

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    This is a list of the best anti-cancer herbs (I don't know the english name of some of them)

    Yarrow, artemisia annua, mistletoe, graviola, moringa, calendula, chamomile, stinging nettle, Cat's claw, Pau d'arco, green tea, Daigrenmotian Kalanchoe / Kalanchoe Pinnata, stevia rebaudiana, Aloe Vera, Galium aparine, fire cactus plant, Essiac herbs tea, laurel, enebro, ginger, cinnamon, curcumin, dandelion... Any other herb that I'm forgetting?



  • anotherone
    anotherone Member Posts: 555

    frankincense, oregano- or may be you have them listed under Spanish names so I do not recognise them

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    Anotherone: Yes, too! The ones that I included in the list can be taken in tea. Oregano essential oil can be taken in capsules and frankincense is for use on the skin. I use it too, it has an exquisite aroma!


  • simone60
    simone60 Member Posts: 952

    Hi Sonia,

    I had bought some frankincense awhile ago but never used it. What is the best way to use it?

    I stopped the COC protocol today. I was so sick yesterday from the higher dose of pills with Nausea, vomiting, diarrhea. I'll call the COC tomorrow to see if there are other options, maybe go back to the smaller dose or a different generic brand? I am not sure. I'm very disappointed, I've read so many good posts about how good the protocol works.

  • anotherone
    anotherone Member Posts: 555

    sorry to hear that , simone.

    The guy I spoken to last Saturday says that the same effect as from metformin and statin respectively can be achieved by berberine and lycopene so those 4 medicines are not the only suitable ones likely.

    I use frankincense oil by mixing it with olive one and applying on my skin over the chest and neck and back area a few times daily

  • simone60
    simone60 Member Posts: 952

    Thanks Anotherone. I'm going to ask about those when I see the IMO Wednesday. Maybe switching to fenben, berberine, doxy, and lycopene will give the same result.

    I read a post yesterday on Jane's website from a woman who has MBC for 29 years. She has been taking doxycycline for something else all that time along with a few other repurposed drugs.

  • Xxxxxxxxxxxxxxx
    Xxxxxxxxxxxxxxx Member Posts: 551

    Simone: I understand you very well, I had to stop some supplements too due to diarrhea. Metformin is known to cause diarrhea and, in addition, doxycycline also kills the intestinal flora. Maybe you can replace metformin with the supplements mentioned by Anotherone. A probiotic wouldn't be a bad idea either.

    I also use the frankincense oil mixed with cream and dmso on the skin. I am using it for rads because it is very healing and regenerating as well as anti-cancer.

    I still believe that fenben is the most important part of the protocol, so if you can take it together with some vitamin e and curcumin without feeling sick, I think you will have good results.


    I also take MSM, turpentine, iodine, lysine, ALA, and colloidal silver. Uf! Iodine really helped me get through the whole chemo without a cold (and I had low wbc counts)I eat a lot of apricot seeds a day ... and when I finish the rads, I will take vitamin C, magnesium, potassium and boron again. A bag of things! LOL

  • anotherone
    anotherone Member Posts: 555
    • simone , good that you found an IMO . I must say I miss someone who would oversee all this sea of supplements and medications I am thinking of/swimming in.
  • simone60
    simone60 Member Posts: 952

    Sonia,

    Thanks for all the info. I think I'll try the frankincense tonight on my scar from my reconstruction. It can't hurt.

    Anotherone,

    I know what you mean. It is overwhelming sometimes with all the supplements that are out there. I've read so many conflicting articles on some. For instance milk thistle. I used to always take that but I've read lately it is not good for er+ breast cancer.

  • lilahope777
    lilahope777 Member Posts: 27

    Simone - Are you (were you) taking the Metformin Immediate Release (IR) or the Metformin Extended Release (ER)? I have read that the Extended Release version causes less digestive upset. I have my Mom taking Berberine, so I hope it's as effective! Not sure what to do about the doxycycline.

  • santabarbarian
    santabarbarian Member Posts: 2,311

    I take metformin I believe ER (will check) no issues w my tummy.

  • lilahope777
    lilahope777 Member Posts: 27

    I'm having some difficulty determine which supplements are okay for my Mom to take as well (hormone positive, currently taking Letrozole, soon to start Kisqali). So far, I've determined that she should not take:

    • Artemisinin
    • DHEA
    • Luteolin
    • Silymarin (Milk Thistle)
    • Turmeric (Curcumin)
    • Quercetin
    • Resveratrol
    I hope to run the other supplements by her GP tomorrow and hope that she is open-minded. I'm trying to target the metabolic pathways as discussed in Jane McLelland's book. For example, I am unsure if she should take Cimetidine as it is listed as a Moderate Inhibitor of of CYP3A. Letrozole, from what I have found, is metabolized by CYP3A4 and CYP2A6. If anyone more knowledgeable than I can shed some light, would love to hear your take on it.
  • simone60
    simone60 Member Posts: 952

    Santa\Lila,

    I was taking ER version of Metaformin.