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Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer?
Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer? Dec 6, 2024 Dr. Donald McDonnell discusses his research on estrogen, eosinophils, and triple-negative breast cancer. New research suggests that estrogen plays a role in allowing hormone receptor-negative breast cancer to grow. This is because estrogen limits…
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Letrozole and Tendonitis?
Hello all! I am coming up on 6 years of AIs with Letrozole being the most recent one. I had been on Arimidex but developed trigger thumb and fatigue over time so I switched to Letrozole. I have been okay for the most part but I now have tenosynovitis in my left wrist which won't go away and a new tendon issue on the top of…
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Break from Letrozole for 2 1/2 months
I will be going back on letrazole after a break after 2 1/2 months due to sudden onset of constant palpitations and one short episode of a/fib. I had to get a cardiac work up and getting that done has taken time. Getting in to see a cardiologist, wearing a zio patch for two weeks, waiting for the results and then scheduled…
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Early Stage Breast Cancer - anyone on Letrozole and Ribociclib?
Wondering if anyone has been diagnosed with Early Stage Breast Cancer and on AI/Ribociclib regimen? I’m going to start after radiation and wondering how your treatment is going and if there are any tips out there! Thanks in advance!
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Ribociclib/Kisqali with Letrozole - Any one on this combo?
I am starting this new forum for all those who are on this newly approved drug combo. I started on Kisqali/Letrozole combo 6 weeks ago and so far it has been tolerable. Letrozole gives me joint pain and low back pain. My oncologist has asked me to take this on alternate days. Would love to hear from others about their…
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AI’s after 10 years?
It has been many years since I checked in but it’s so wonderful to see how much this thread has grown! I remember clinging to the hope here when I was first diagnosed, and now am myself more than 13 years out from my stage 3 diagnosis! My question for this wise group is how many of you have remained on an AI for more than…
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Letrozole Side effects-- throaty
Have been taking letrozole for about 4 months after DCIS (w/clear margins), and preventative radiation treatment. Seem to be free of noticeable side effects except it appears to cause a cough and a 'drippy' feeling in the back of my throat. I confirmed this by going off it for 2 weeks, when these symptoms disappeared. Has…
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Hormonal Therapy for Breast Cancer May Lower Dementia Risk in Older Women
Hormonal Therapy for Breast Cancer May Lower Dementia Risk in Older Women Sep 9, 2024 Protection varied by race and decreased with age. Read more…
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Aromatase inhibitors
Hi I am post lumpectomy, micro metastasis in 1 removed lymph node and now faced with the far more daunting ( to me) prospect of taking letrazole oestrogen inhibitor. Does anyone have anything positive to say about them? All I hear is the negative side effects. Others experience would be very welcome. I’m 61, normal weight,…
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Doing Well on Aromatase Inhibitors (AIs)
I read a suggestion that someone should start a topic for women who are NOT experiencing severe SEs while taking Arimidex, Femara, or Aromasin. I'm about to start taking Arimidex and when I read about the potential SEs I get discouraged. Maybe others would also like to hear about positive experiences. We would love to hear…
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FEMARA
I STARTED TAKING FEMARA ABOUT 2 WKS AGO. WHEN DOES THE SIDE EFFECTS START TO KICK IN Edited by Mods to add content from the main Breastcancer.org site on Femara: Benefits, Side Effects and More
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Psychological reactions to aromatase inhibitors.
I'm sure this has been discussed on other pages but I want to start a thread specifically for this discussion. For the second time, I have had a severe neurological response to Aromatase inhibitors. The first time I was told there is nothing that would help so I quit taking the meds That was 6.5 years ago. I recently had a…
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Women on Ovarian Suppression + Hormonal Therapy Unite!
Hi all! I'm starting this thread for those of us premenopausal women who are receiving ovarian suppression treatment (Lupron, Zoladex, oopherectomy, etc.) plus hormonal therapy (tamoxifen, exemestane, or another AI). For me, there's a lot of fear and worry over how this will impact my overall well-being... how it will age…
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Switching from AI to Tamoxifen - Bone loss
Hi, I just met with a new oncologist after the retirement of my previous one. I have been on an Aromatase Inhibitor for six years with worsening bone loss. Taking Fosamax. The new oncologist suggests switching to Tamoxifen. Total treatment time would be 8 years vs. target of 7 if I stay on AI. Has anyone had or considered…
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Stopped Letrozole for One Month
I am curious if anyone has taken a break from hormone inhibitors for a month. I had surgery in January 2023 for invasive lobular cancer of the left breast and had a mastectomy. My oncotype was 13% and I had radiation therapy for 5 weeks. One lymph node was positive. I have been on and off hormone inhibitors since last…
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Been on Letrozole almost 4 years IDC
I will not list all the SE I had during my last 4 years on the 2 ALS I tried but it was not good. I took a 41/2 week break still had some major foot pain, sores not healed up in nose and very itchy scalp any how I am now cutting my Letrozole pill in half and taking it every other dayIF my SE come back in full I am done. I…
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fatigue on ovarian suppression and AI?
It's been a long time since I've posted here. I was so scared when I was initially diagnosed but have gotten through a lot - surgery, chemo, and several years of endocrine therapy - no small feat! I'm finding endocrine therapy mostly quite tolerable but have pretty consistent fatigue. Does anyone else experience this on…
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Aromatase Hormone inhibitor “5 year pill” side effects?
Has anyone used these? what were your experiences as far as side effects? cardio-muscular-bone damage?
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Half and quarter doses of letrozole
I quit the letrozole because of the horrible sise effects. Exemestane was awful and lost 3/4 of my hair and had to use a walker to get around. I started the baby Tam (tamoxifen)and had to quit after 3 weeks the side effects were so bad. I then started the 1/4 tab of letrozole and the side effects were tolerable so I tried…
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Introducing myself from Nairobi, Kenya
See first comment below for Rosebessie's story and welcome her to the community! This discussion was created from comments split from another thread.
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Breast Cancer Index
I am near the 5-year mark of my endocrine therapy. I am meeting with my MO next month. She ordered the Breast Cancer Index test; the result is that I am not likely to benefit from extended endocrine therapy. Does it mean I do not have to continue with my monthly Lupron injection and letrozole beyond 5 years? How do…
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Ibrance 100mg and femara
Hi, I have an oligometastatic and I have been taking these medication for 6 months. My blood count white cells were sooo low that my doc decrease the dosis. And I felt much better. Although count doesn’t increase much. I have shots regularly to increase white cells. My energy levels are usually good. Sometimes I get sick…
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Obesity Ups Recurrence Risk in Women Treated With Aromatase Inhibitors
Obesity Ups Recurrence Risk in Women Treated With Aromatase Inhibitors Nov 24, 2023 The risk of breast cancer recurrence is higher in women with obesity treated with an aromatase inhibitor. Read more…
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Weight gain on treatment
I am currently on letrozole, zoladex, and verzinio with stage 4 bone mets with a hip replacement, kyphoplasty and spinal injury. It is hard to be active because of pain but I try to work out 3 days a week...I have gained 20 lbs in 6 months and am only eating 1500 calories a day. Looking for advice- I am 5"2 and never been…
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What Helps Women Stick to Hormonal Therapy Treatment Plans After Surgery?
What Helps Women Stick to Hormonal Therapy Treatment Plans After Surgery? August 25, 2023 Lowering medicine prices seems to be one of the best ways to help women stick to their hormonal therapy treatment plans after breast cancer surgery. Read more…
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Progression after ribociclib (csk4/6i) and letrozole
Hi I had her2 neg er+ breast cancer in 2018. In 2022 i had recurrence in my bones (all over with 3 collapsed vertebrae) and liver. I was on ribociclib and letrozole that worked really well, pet was negative and most metastasis disappear. In August I had liver recurrence. Blood test and markers are ok and i feel well so i…
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Progression after ribociclib (or cdk4/6) and letrozole
Hi I had her2 neg er+ breast cancer in 2018. In 2022 i had recurrence in my bones (all over with 3 collapsed vertebrae) and liver. I was on ribociclib and letrozole that worked really well, pet was negative and most metastasis disappear. In August I had liver recurrence. Blood test and markers are ok and i feel well so i…
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Any POSITIVE stories about AIs or Tamoxifen?
I am seeing a lot of posts seem to indicate that AIs are frequently stopped due to side effects that are not bearable. I am on Tamoxifen and expect my onco to recommend me changing to an AI. I have gained at least 10 lbs since starting T just shy of 2 years ago. I do have joint pain (specific to the hip area) but am sure…
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Kisqali Plus Hormonal Therapy After Surgery for Early-Stage Breast Cancer Reduces Recurrence Risk
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Unusual side effects of Aromatase Inhibitors
Trying to find resources or breast cancer sisters and brothers' experiences who are using AI and have unusual side effects that are not on the medication list. In my case, my skin color has changed from pale white to orange/yellowish. My blood tests are normal including all liver tests. Anyone else has a similar side…