Ringworm drug for dogs (Fenbendazole) might also cure cancer
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So It took me a whole day on and off to read through this thread..Thanks for the PM Frisky telling me about this thread. Here is my question:
Joes protocol should not be taken by people with ER+ HER2- cancer right?
I believe someone mentioned why the Curcumin and the Vitamin E would not be good for Hormone Receptor Positive breast cancer?
-Nicole
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Jut told today, after a cranial biopsy my wife's lining of the brain, the Dura or meninges, is cancerous. It's inflamed and putting pressure on the brain. This pressure has caused seizures, which via medicine, are under control. I want her on Joe's meds as soon as possible. I've seen statements from people with actual brain cancer say it worked for them. Maybe it will work for my wife, she has TNBC, which seems to be under control with Halaven.
MikeW.
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Mike...sorry to read about your wife...Joe's protocol seems to work on various cancers while patients undergo traditional treatments, therefore she might benefit from it as have so many other people.
This group started about a month ago...too soon to know how's working for MBC....
Wishing you and your wife the best outcome
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The vitamin E in the amount Joe recommends should not be a problem for ER+. There was a clinical trial in Malaysia, sponsored by the palm oil board testing their tocotrienol blend on ER + women, combined with tamoxifen. I believe it was a failure to show benefit, but there was no reason to believe a small amount of full spectrum Vitamin E would be detrimental.
As for the curcumin, its more the worry that it might interfere with drug metabolism, than fear the curcumin itself would be harmful to ER+ patients. A knowledgeable researcher (I mentioned above) in the breast cancer field in fact recommends curcumin and says that its propensity to interfere with aromatase inhibitors is purely theoretical, and not actual. I am sure that if he thought the curcumin itself would be harmful to ER+ patients he would not recommend it.
If anyone has found anything suggesting otherwise, I would like to hear about it.
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I would like to know about the curcumin as well, it's the only thing of the protocol I am not doing.
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Goldie, I'm in agreement with you. I'm not doing it curcumin either. When I was on Ful/Ibr my Onc said not to take it. (and they are very liberal on supplemens)
I have read that turmeric, pills or cooking, is better than than curcumin, but I don't know that for sure.
Mike, welcome to our little group. If you've read though this entire thread than you know that we're just a small group of people who believe in Joe's protocol. We share knowledge, encouragement and most importantly Hope. Others have succeeded using FenBEN and there's no reason that it cannot benefit your wife. My prayers are with you.
Hope that you've read Joe's blog which explains his journey, and then sign up for his FB page which if full of testimonials. Believe Mike, with every fiber of your being, and encourage your wife to do the same. The power of positive thinking Is enormous.
We're here for you
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If only they would do blood tests on women on letrozole to determine their levels of estrogen, then we would have feedback as to whether the letrozole is working, and whether a supplement interferes with it. I know my wife hasn't been tested for estrogen levels since she first went into chemopause following her first chemo back 8 years ago.
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re curcumin:
- curcumin is better than tumeric as curcumin is the active ingredient in tumeric.
- Many MOs are fine with curcumin Some are not. The integrative MO I consulted put me on it during chemo... still on it. I take 6000 mg/ day (2 doses). My chemo wasTaxotere & Carboplatin, and I had TNBC.
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Huband11 thanks for the info... I just found this..which speaks to the Tumeric and Curcumin
http://sagecancercare.com/sage_advice_blog/curcumi...
Although this speaks to Tamoxifen ... it is a hormone therapy drug.... I am on Ibrance (just started last week) and Faslodex and Letrozole, lupron and xgeva...I worry that if I take the Curcumin I won't be able to metabolize all the meds I take. From what I have read on here just taking the feben alone will not work?
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NicoleRod, thank you for posting that. That is really recent and relevant information, especially considering it considers human patients and their (tamoxifen) drug metabolism as affected by curcumin. Really gives one pause for consideration to taking curcumin along with any drug that relies on cyp3A, cyp2c9 or perhaps cyp2d6 (as is used for tamoxifen metabolism). Hopefully the fenbendazole doesn't actually need curcumin to work on cancer.
I can't access the published article, but found some commentary on it at a site called Beyond Conventional Cancer Therapies. The reduction in endoxifen levels was mild, 8 and 12 percent for curcumin and curcumin plus piperine.
https://bcct.ngo/search-therapies/search-therapy-summaries/curcumin
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Curcumin is generally regarded as safe by the US Food and Drug Administration (FDA). Epidemiological evidence and several clinical trials confirm the safety of curcumin up to 12 grams per day over several months.51 However, compounds in curcumin can bind to iron and reduce iron's availability, a concern to people with anemia or iron-storage problems. Iron levels may need to be monitored with curcumin supplement use.52
Preliminary clinical evidence shows that cucrumin may slightly reduce the effectiveness of tamoxifen. In a study of breast cancer patients, researchers in the Netherlands gave tamoxifen with or without curcumin 1200 mg three times a day. The group taking tamoxifen in combination with curcumin had about an 8 percent decrease in endoxifen levels. If the curcumin was compounded with piperine (often done to substantially improve curcumin absorption), endoxifen levels were further decreased by 12 percent.53 Read more about this study and implications for use during tamoxifen treatment in the Commentary section below.
Dr. Lise Alschuler cautions that curcumin should not be taken with some drugs (cyclophosphaide, anastrozole, exemestane, letrozole or erlotinib, or therapeutic doses of warfarin),54 and the TRC Natural Medicines database lists several interactions with chemotherapy drugs, diabetes medications and other drugs that lower blood sugar, estrogens, drugs that slow blood clotting, and other drugs. Medical supervision is recommended at doses higher than those typically found in foods.
Dr. Weil and Alina Health provide these cautions:55
- Don't use turmeric if you have gallstones, bile duct dysfunction, hyperacidity, or stomach ulcers..
- Pregnant or lactating women shouldn't use turmeric supplements without their doctors' approval.
- In rare cases, extended use can cause stomach upset or heartburn.
- Piperine can slow the elimination of some prescription drugs including phenytoin (Dilantin), propranolol (Inderal), and theophylline. Some evidence also suggests that curcumin can interfere with certain chemotherapy drugs used to treat breast cancer, so if you're being treated for this disease, be sure to discuss the advisability of taking curcumin with your physician.
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This article was sent to the FB group from a genetics professor! I covers the three pathways that we know about but adds so much more. Hope curi ous comes along to explain it better than I can. (way way better)
Curi ous is this article saying it works better THAN Toxal? or better results are obtained when doing both?
THANK YOU
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Snooky thank you so much for this scientific explanation for the success of this therapy...
May we all benefit....
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Snooky- This paper was also posted above by Miao
It shows Fenbendazole affects microtubules, but only modestly, and also helps to block the uptake of glucose (sugar), which cancer cells rely on.
Fenbendazole anti-cancer activity was even higher when combined with taxols, or even more so when combined with drugs that inhibit glucose use. They did not try other combinations, and its effects on the immune system really should be tested. It is crazy, given how long the potent anti-cancer effects have been known, and that some people have taken the drug for 2+ years without developing major toxicities, that there is only one clinical trial testing mebendazole, as a monotherapy for pediatric brain tumors. C'mon, we can do better than this!!!
PS. Okay, well in Egypt they are doing a trial to see how mebendazole affects Folfox + Avastin on colorectal cancer.. Hopefully the chemists are optimizing mebendazole and it will show up in more trials in the future?
https://clinicaltrials.gov/ct2/show/NCT03925662
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Frisky-- Doesn't this article explain the reason for coffee enemas? (and my use of Epson salt flushes)
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Snooky I'm not sure about that because I couldn't read the whole article, but, any detoxing techniques would lighten up the toxic load created by the current therapies. I totally agree with you.
What I got out of it, is an explanation as to why the current thinking and modalities fails us 99% of the time: (we do have couple long term survivors to look up to)
That which does not kill cancer stem cells makes them stronger. That the free radicals and dead cancer cells toxicities generated by the chemotherapy will kill us first, long before it kills the cancer stem cells, which inevitably rebound stronger and more aggressive than ever.
Declaring a war, without understanding the enemy is the height of stupidity. Aggressiveness without knowledge leads to repeated failure, which is the only reality we can count on...Trump's policies, so far, offer anounobstructed view of what happens when power and ignorance get mixed together.
So we must try to think outside the box, and use the therapies that the cancers survivors have generously shared with all of us, in combination with traditional TXs, as they did, to improve the odds..
May God help us in our quest! May we be victorious and help others till this disease is no longer a nightmare for the large percentage of humanity.
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this letter is an email sent to Joe which he posted on his FB page:
Just received this email which is a first I believe
Message: Hi Joe I read your story with great interest. A friend of mine has skin cancer and being a farmer this created a serious problem for him. He tried other remedies such as the marijuana cream which did not work. He also had some of them surgically removed. I told him about your story and gave him of your medicine but added that I had not read anywhere whether it helped for skin cancer. When I spoke to him in the previous week, he stated that there was a remarkable improvement. The large skin cancer on the top of his head felt dry and dead. I also telephoned my brother and told him about this product as well. He was sceptical to say the least. I then called my farmer friend and asked him to take a photo of his skin cancer and then take a follow up photo in a couple of weeks time so that I forward these to my brother. Mr farmer friend stated that I called him to late as all of his skin cancer is gone. The large one on top of his head had simply dropped off since we last spoke. This was after taking the product for only 3 weeks. Just thought I would let you know so that you can in turn let others know that it tackles skin cancer as well. Thanks and Kindest Regard
---------------I took out all names for privacy. Also, it does not mention what kind of skin cancer it was. S
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Just read on Joes page that PARABEN is a filler in the de-worrmers for farm animals. Paraben is not good for brest cancer. De wormer for fish/dogs/cats are all ok
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Thank you Snooky, this was very helpful. I read on FB that Merck states there is no Paraben in Panacur c.
I am on the week 3 on the protocol. No SE. Praying for everyone to have good scans and never loose HOPE
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Snooky thank you for posting such an inspiring story....
Blueshine thank you also for checking on the parabens...that means we are all good to go
Cureious you'll be happy to know that this Thursday I'll be finally taking this show on the road, as I manage to screw my courage to the sticking place....just got off the phone with my MO that has reassured me that the new palbo won't kill me...and might stop progression in my liver...
I have decided that my next step—when this is over—will be to send a sample of the lesion in my liverto the Nagourney Institute for a functional analysis. I would feel much better about chemotherapy if I knew beforehand what can help and what is useless
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Mia, I wish you again luck with the new treatment !!! I think, tased on everything that i read, your SE will be minimal , because of the fenbendazole and the supplements.Remember Joe was on a trial too and he was the only one who didn't fail . Have faith in what you are taking. we are all with you!
Gentle hugs Elena
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Has there been anyone with MBC hormone positive that has had success on Fenben? It seems like I am only seeing other types of cancer but not MBC...?
I do agree with those that have hormone positive MBC and ibrance and other meds have stopped working for them so they are doing the Fenbendazole. I just started the ibrance and I am actually considering emailing my MO in the next few weeks with an article about the Fenben and getting her take on it.
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Good luck with the trial Frisky. I had to do a trial a couple of years ago to access Ibrance in the U.K. you are so well looked after ontrials and it was great to text my Onc whenever I had a question that said I text my new Onc all the time since being off the trial. I like him to know that I am still around 😀. Routing for you Frisky and hoping the meds will be kind to you.
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Nicole....no oncologist on this planet is going to tell you, it's okay to take the FZ or any supplement for that matter. They base their prescriptions and decisions on a predictable list of medications. The results of clinical trials, and there's none being considered right now. And even if there were, it would take 10 years for the results to be approved, and we'll all be gone by then....
So if you start talking about this experiment, all you will be doing is jeopardizing the availability of FZ as an over the counter medication for those of us that are ready and willing to try.
You might want to consider waiting till the results are in—from the people on this board with your same diagnosis and the same medication—before making a decision.
Best of luck to you and all of us.....
Elena, Chico....thank you for the support!
Tomorrow, i will be at the hospital the whole day...they will be checking on my vitals every 2hours....this morning they did the final testing, and now I'm quite excited to be starting this new TXs
Snooky I’m thinking about you and wondering how your arm is faring? Have the swelling and redness gone down? Big hug!
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Frisky, you've said the crude true. I would't even considerate to mentionate FENBEN to my MO. HUGS
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I don't think my MO reading this article https://www.nature.com/articles/s41598-018-30158-6...
that I read would jeopardize anyone trying Fenbendazole. This is a veterinary drug that people need for their pets and I don't think they will stop selling it because of that. I said I was considering emailing her to get her take on it that was all.
I also didn't realize that as you said "It would take 10 years for the results to be approved, and we'll all be gone by then...."
I thought like you...(since I only have been on the Stage IV train for a month now) that I will be gone before 10 years but lately after hearing from all the positive caring women here I was trying to be positive and based on them all mentioning to me numerous times that new treatments are now being approved every year and there is no reason not to believe that we can live 5 year or 10 and even more years I was starting to think that is quite possible.
I guess hearing you say that is little disheartening. I certainly do not want to jeopardize people trying Fenbendazole..that would never be my intent especially since I hope to try it one day myself
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Reality Check!
An estimated 155,000-plus women (and men) in the U.S. currently live with "mets," or metastatic breast cancer. ... While treatable, metastatic breast cancer (MBC) cannot be cured. The five-year survival rate for stage 4 breast cancer is 22 percent; median survival is three years. Annually, the disease takes 40,000 lives.Oct 13, 2016
- Median years of survival after an MBC diagnosis: 2-3 years (was 18 months in the 80's [ACS, 2007])
Metastatic Breast Cancer survival rates
- Median survival after diagnosis is three years. There has been no statistically significant improvement in the past twenty years.
(American Society of Clinical Oncology [ASCO] Report – 2008
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I didn't need the reality check I was the one quoting those stats as well in other threads saying I was scared and couldn't believe I only had a 26% chance to live 5 years....it was all the women I said it to on here telling me not to look at those stats and that they are outdated and with the new meds people are living longer than that.
I agree it's horrible and sad.
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Nicole, don't waste your time talking with your MO about Fenben or any other complementary theraphy. The MOs aren't allowed to prescribe anything outside the standard treatments. Of course you can live many years with this desease, everyone is different. Sorry about your recently dx. HUGS
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Thanks for the hugs right back at ya!
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It's a tricky decision whether to mention extra-curricular treatment ideas with your oncologist. My wife and I have given up on that. Fear of liability on the part of Doctors for the consequences of any unapproved treatment alone would have them tell you not to do it. Yes, you are working without a net, so to speak, but if anything goes wrong I feel most oncologists will blame it on the alternative or complementary treatment. As well, they may hold it against you, and if you want to go into any clinical trial, I fear they may reject you on that basis. You will be perceived by your Oncologist as untrustworthy, unreliable and a danger to your self. We have medical people in our family and I have given up on talking to them about these issues. They base opinions on the most uninformed assumptions, old nonsense they were told in school and make snap opinions to condemn ideas. As far as I am concerned, I do my absolute best to ascertain known drug interactions, potential drug interactions, toxicity, estrogenicity, cytochrome enzyme inhibitions and base the decision on risk + cost vs likelihood of reward.
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