Ringworm drug for dogs (Fenbendazole) might also cure cancer
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Goldie so happy you DO NOT have liver mets
!!!!!I think I have that CA- 15 -3 on my blood work but it says this...
CanAg 15-3 Range: 0.0 - 25.0 Result: 23.6
CanAg27.29 Range: 0.0 - 38.6 Result: 32.1
Are those tumor markers because my range and result is so much different from your test? If so, I guess that is good that I was normal..but then again my MO in NY had said mine have never changed?
My bilirubin and yours are the same...I was 2.0 (this was 2 weeks after my faslodex injection and mid cycle of ibrance) My bilirubin normally my whole life usually runs a little high at 1.5 with 1.3 being the max in the range. After I get my 1 month labs next week I will see if the bilirubin is back to like 1.5 if it is then I know mid month its probably up from the faslodex because the doctor said that was one of the reasons she didn't want to prescribe me the Mebendazole and stuff because my liver was already trying to process the faslodex..and the Ibrance (though she specifically mentioned the faslodex).
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Nicole, looks to me like you have some good numbers, better than mine and I don't have any organ involvement!
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Thanks...TODAY...I needed to hear something good
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Snooky, yes, I remember that Ted recommended iodine, mixed with 1 drop of hydrogen peroxide to "oxidize" and become more assimilable for cells ... I am also overwhelmed by the amount of supplements I'm taking. I need a plan too ... but I think iodine is one of the "must be". It is an essential nutrient that is scarce in food, and is also antibiotic and protected against radiation (and we have a lot of that) ... I'm planning to return to the fenben when I heal from radiation
Goldie: glad to see you!
Soft hugs like this to all of you!
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Sonia you are not going to do the fenben anymore?
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Nicole, yes, I'm going to do the fenben protocol again when my skin is cured of radiation. In my previous fenben cycle I had neuropathy (I had recently finished taxol and I think my body was not yet healed of neuropathy) Meanwhile I take other supplements and plants, but I plan to make fenben my main protocol ❤
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Oh when you said "return the fenben" I thought you meant send it back LOL
but you said return to the fenben..lol I missed that.0 -
My english language management doesn't help, that's for sure ...
LOL, I love when someone posts that emoticon, I always imagine the face of the person making that gesture and that makes me laugh ... Well I'm going for my daily rad. Have a nice day!
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don't worry Sonia...your english is just fine as is!....
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If you are on Ibrance, go to the thread entitled "Ibrance and Atorvastatin" -- posted by Jackie (sp) -- she commented that there could be a serious reaction between Ibrance and Atorvastatin, and there is a writeup about this that is just plain scary --
See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC55118...
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That's one hell of a scary story BevJen....
All ibrance patients should be warned...I wonder how many are taking Lipitor and don't know what can happen...I wonder how many women have died already without doctors figuring out the correlation...obviously, no warnings have been issued so far...the use of statins is very common....
As far as organizing the numerous supplements we buy and need to take...I tend to rotate them, since I was told by ALL my numerous doctors, including an oncologist that specialized in natural medicine, that the body gets used to them and they no longer work as expected. So give your body about a week off from a particular supplement, and rotate to something else..
Ah....one more thing....I watched the video with Jane that someone had posted a few days ago, and it has unfortunately confirmed a problem with a particular metabolic pathway. Which is the Glutamine pathway, very popular among breast cancer cells.
There's no off-label drug we can take to block this pathway because normal cells, WE, need glutamine, as much as the cancer cells do. Thus, if your cancer is metabolically driven by glutamine, the clinical oncology drugs we are taking are not going to do much. But it will likely slow down progress if your cancer is not feeding on proteins, specifically the glutamine.
Drugs that suppress glutamine are considered very dangerous...so until someone comes up with a solution, we are still fckd...of course FZ can always save the day on it's own....let us pray!...
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Wow bev thanks for posting that...that is so sad and scary.
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anotherone, do you happen to know what medication is prescribed by the COC to block the Glutamine pathway?? Is there such an animal??
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Doxycycline is the one that's prescription
Looking at the triangle she uses,
- metformin, berberine, EGCG, curcumin and doxycycline (among others) are all active against feeding on glutamine.... You can google Jane McClelland Metro Map and the image comes up.
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Santa, I have the Metromap, and that's what I've using, but the problem with the glutamine is a well known one that she didn't resolve, not according to the latest interview she had given on the subject. She will have to revise the metromap.
Metabolic research being conducted at MSK, of all places, report a lack of solutions, and MD Siegfried at Boston University, aware of this intractable conundrum, is conducting clinical trials that rely on a dangerous drug and a confusing and convoluted diet that's complicated at best.
The problem is that we can't live without glutamines...and can't starve that pathway yet with safe off-label drugs. Of course, I would rather be wrong about this one, because it explains the type of resignation that I can pick up just about everywhere doctors hear the mention of a cancer cures.
I’m willing to bet, that’s also the reason why FZ doesn't work for everyone....
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Frisky, maybe you can find this interesting. It is in spanish, you will have to use google translater (I"m sorry)
https://blog.terapiametabolica.com/inhibicioncompe...
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frisky , they don't even explain much about pathways and what is for..I guess if someone would figute out if there are any differences between the pattern in which cancer and normal cells using it it could be targeted..
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Sonia, this what goggle translated, which seems very clear...thank you
In the case of Glutamine there is a complication, since it has the function of carrier for the elimination of ammonia in the body, a compound that is toxic to animals, so that its presence can not be suppressed by diet and only It has the structural analog to avoid obtaining energy for the development of the tumor. In this case, 6-Diazo-5-oxo-L-norleucine (DON) would integrate a second category of structural analogs that would bind to the catalytic site of the degrading enzyme, thus avoiding glutamine deamination. The discussion about the role of enzyme inhibitors, whose joint action to that of the structural analogues, would complete a scheme to inhibit the metabolic pathways of cancer is pending.
DON, is what Siegfried is testing I think, in conjunction with a modified keto diet...but is very toxic and dangerous according to the people in the interview posted above...
DON is a cytotoxic inhibitor of many enzymes of nucleotide synthesis. It could be shown in vitro that DON treatment led to apoptosis, the programmed cell death. Different pathways were investigated. So it could be shown that the inner mitochondrial membrane was damaged,[14]and single strand DNA breaks were observed.[15] The exact mode of action remains unclear and needs further research.
DON is not approved as pharmaceutical agent, but is tested in combination with a recombinant glutaminase in clinical trials for the treatment of different solid tumors.[4]
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anotherone, thanks for the answer, I figured as much...I'm not surprised...I guess they hope blocking the other pathways might be helpful, it all depends on what cancer cells prefer, but they don't think twice before switching feeding grounds.
I guess the COC can't prescribe DON without proper medical supervision...so here we go....more waiting for Godot....unless we get treated by Siegfried that seems to me....kind of half-crazed....
https://www.ncbi.nlm.nih.gov/pubmed/30181331
We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine.
According to this study, DON was studied extensively in the '80s but abandoned because of SE. they are currently re-evaluating it using smaller doses.
Until the DON conundrum is resolved, the solution is to minimize the proteins, and increase, what else VEGETABLES, all the colorful one's...no pizza and tiramisu are not part of the program....
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BevJen,
That is a scary story. I wonder if quercetin would have the same issue. I looked up both for drug interactions and atorvastati n is listed as a moderate risk with ibrance.
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hi all,
I’ve been lurking since July (my stage iv diagnosis). Frisky, I saw your concerns about the gluatamine path so thought i’d Jump in. I’m doing Joe and COC protocol and Jane’s off label drugs/supplements. Jane’s Facebook group had a specific metro map for tnbc which is what I have and the glutamine paths are blocked. I created a google sheets of jane’s book and the metro map, and an attempt of organizing all the info. It’s a work in progress so be gentle. But it might be helpful. https://docs.google.com/spreadsheets/d/1eAQ7JvpZ7lShVRUc_MfGT28TruZmts0p1Th7ACy8LME
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Frisky, I posted the link before you edited your previous post, from what I see, you were already aware of the dangers of suppressing glutamine ... my post was redundant...
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Oh gesh guys, all this negative talk and scientic things that are not sinking into my chemo brain, ruined my great day. Why? I pooped. Twice!!!
I got constipated while on taxol and it's an on going struggle. I've
been taking double dose of Senna and stool softeners.. While they are helping, my stools are still way too hard. But today it was easy peasy. And normal consistently.
So, does anyone know of something more effective than Senna and stool softeners? Not talking colon cleanses like enemas and salt flushs. Just healthy normal bowl movements.
Drives me crazy thinking of all those dead cancer cells in my colon.
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is all good Sonia...after your post we have a name for the drug under consideration.
Shiteachmama, thank you for making your detailed homework available to us...I have reviewed it carefully....and OMG...you've managed to create a structure out of the convoluted narrative in Jane's book...I will download it and use it in conjunction with the metromap.
Please stay in touch and let us know when and if the information is updated. We are all very grateful for all the great work you're doing...Snooky...you might want to increase fiber and liquids consumption, it should help move things along...
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Encouragement from Joe's page. T his is fantastic!
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Hi everyone. This is my first post. Joe asked me to join this group to share my experience with everyone and although I swore I would never join fb, how could I say no to Joe? I am seeing positive FenBen results! On March 27 I had my uterus, ovaries, fallopian tubes, and two sentinel pelvic/aortic lymph nodes removed. Dx was uterine Carcinosarcoma stageIVB. A mixture of Carcinoma and sarcoma, two cancers in one. Only 5% of uterine cancers are this rare type but account for 15% of the deaths. Extremely aggressive. Already extremely advanced. The post surgery PET showed "extensive regional and distant metastatic disease within the pelvis, abdomen, and chest. Multiple intensely FDG avid lymph nodes, two examples given were SUV 14.6 and 8.75.
It was also in at least seven bones. I immediately started cannabis oil, THC and CBD 60mg a day and I started vitamins and supplements from a naturopath. I started chemo Paclitaxel and carboplatin on May 2. Mets too extensive for rads. Then, 😃, on July 7 my fenben arrived 😊. I started taking Joe's protocol, 222mg dose, every day, I wouldn't stop, couldn't stop, I was so psyched to get started and had waited weeks to get the meds as I live outside the US and needed someone to bring it as Amazon will not ship supplements or meds internationally. At 13 days the stinky diarrhea came so I took a break of four days. I then had my fifth chemo infusion and the side effects this time were so hard to recover from I decided to quit chemo and throw it all in to Joe's protocol. I repeated fenben again for two weeks and then took a break, then 9 days and break then 6 days and break. I am now taking the regular 3/4 dose. I had a PET on September 19. I had taken 48 doses of fenbendazole over the span of 11 weeks. PET Impression reads: 1-"Excellent treatment response with complete resolution of neck, mediastinal, retroperitoneal, and mesenteric lymphadenopathy as well as resolution of multiple small pulmonary nodules when compared to prior study 3/29/19. 2- Only mild residual FDG activity is identified corresponding to some bone metastasis which have undergone some interval sclerosis indicative of an appropriate treatment response." Thank you Joe. You DO know how much this means to me and to all of us here.0 -
Snooky for constipation
- pear juice, organic dried prunes and chamomille tea - get a good brand and let it brew for 5 minutes - drink twice a day - it will help with all mucosal disturbances from taxol
- first line treatmentis Movicol - osmotic agent - basically it draws water into a dry stool - 1-2 sachet a day max twice a day - start with 1 - chocolate or lemon better taste
It is basically the same principle as Frisky' fiber and water, but during and after taxol I needed this
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Schteachmama, WOW what a great spread sheet. You rock!
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For constipation: take 1-4 pills of magnesium citrate (400mg ea) at bed time.
Psyllium is also good (inert non digestable fiber that makes the stool bulkier).
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thank you Snooky for sharing with us that uplifting story...it looks as if anything goes as far as the amount of FZ is concerned. So happy for that woman! In couple days I will be switching from the doxycycline to the FZ and will increase the dose this time...see if it makes any difference.....
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Sonia how are you feeling after the rads? Are you adjusting to the therapy? I hope your skin is holding up well, I remember they prescribed a cream when i underwent radiations that had calendula in it, it was very soothing...
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