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Abemaciclib Verzenio for Stage IV
Luckylegs and friends on Abemaciclib - I am bumping the Verzenio discussion in the hopes that more people have started abemaciclib. We need to get a community going. I have not started abemaciclib but it is on my short list. Like many I am very interested in how people do on this treatment do, both as a monotherapy and in…
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PET-CT scans after node recurrence (and while on Verzenio)?
Hi everyone. Looking for some advice from all you wise, brave folks. I had IDC 18 years ago; ER+, PR+, HER2 neg/double mastectomy/chemo/tamox/negative sentinel nodes. A year ago was diagnosed with an aggressive axillary node recurrence; surgery to remove 8 nodes, 4 pos, 4 neg. Went on letrozole, had radiation, now 9 months…
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Just diagnosed with ILC mets
Hi, all I had ILC back in 2008. Had radical mastectomy on the right breast and prophylactic on the left. Chemo AC→T, radiation and 7 years of Arimidex. 16 years later I am back in the game. Still in discovery phase. Had FDG Pet Scan that shows liver uptake, had endoscopy that shows little spot in the stomach consistent…
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Important Stage IV Topics and Links for Stage IV Newbies
Here are some helpful resources if you've just been diagnosed with stage IV breast cancer, also known as metastatic or MBC. Join our free Virtual Support Groups for MBC! Do you have metastatic breast cancer (MBC; also called stage IV)? Register: Mondays at 2:00 PM EST, Tuesdays at 8:30 PM EST and Wednesdays at 4:00 PM EST…
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Finishing verzenio
I have just finished two years of abemaciclib, following on from surgery, chemo and radiotherapy. I was lucky that just as I finished radiotherapy, Verzinio was approved in the UK for stage 3 BC patients with high risk of recurrence. Given the pretty awful side effects as well as the timing, it means that there aren't many…
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Low invasive duct alcarcinoma
I had a lumpectomy in October and node clearance december, then radiotherapy for 5 days My cancer was grade 2 low invasive ductal carcinoma I need to go on abemaciclib tablet for 2 years and wondered if anyone is on this tablet thank you
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Verzenio and implant complications
Hello, I am excited to join this virtual community. I was diagnosed with breast cancer in October of 23, stage 2 with one lymph node involvement. I did a double mastectomy, chemotherapy, radiation and I'm now taking anastrazole, lupron injections and had been on Verzenio for 7 months. About 3-4 months after taking…
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Psychological reactions to aromatase inhibitors.
I'm sure this has been discussed on other pages but I want to start a thread specifically for this discussion. For the second time, I have had a severe neurological response to Aromatase inhibitors. The first time I was told there is nothing that would help so I quit taking the meds That was 6.5 years ago. I recently had a…
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Verzenio and hair loss.
I’m going to be starting verzenio in a few days and I read that 30% of people who take this medication experience hair loss. I asked the pharmacist about this and he made it sound like I could go completely bald again like I was from chemo. It sounded like he was reading from a script and I’m not sure if he really knew…
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Imlunestrant Plus Verzenio: New Treatment Option for Certain Hormonal Therapy-Resistant Breast Cance
Imlunestrant Plus Verzenio: New Treatment Option for Certain Hormonal Therapy-Resistant Breast Cancers? Dec 20, 2024 Combined with Verzenio, this new oral SERD may be a good option for advanced-stage breast cancer with an ESR1 mutation. Read more…
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Verzenio stage 2 or3
Has anyone taking Verzenio that is stage 2 or 3 done a dose reduction? Does anyone know if a dose reduction affects the effectiveness of it when taking as a preventative when you are stage 2 or 3? I talked to my physician and pharmacist about a possible dose reduction due to issues with D. The D is not terrible for me, but…
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CDK4/6 inhibitors
If you have taken Ibrance or Kisqali or another CDK 4/6 inhibitor, I would appreciate hearing about your experience. I recently had to stop Verzenio because of unmanageable side effects. Oncologist wants me to consider an alternative in that drug class.
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Verzenio for early stage cancer
Hi everyone. Has anyone taken Verzenio for stage 1 cancer and if so when did you start it? I have been on letrozole for 7 months now and my oncologist just today asked if I wanted to start Verzenio too due to my high Ki67 and 1 positive micromet in my sentinel node. I thought you had to start Verzenio at the same time as…
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Stage III and Verzenio
I may need to venture into the mets forum for SE coping strategies, but I’m wondering if there’s anyone else who’s been put on Verzenio (vs Ibrance or Kisquali) to prevent recurrence? My MSK oncs and Yale onc (I switched to Yale this past summer) all agreed that I should be put on a CDK 4/6 inhibitor. We waited until this…
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Not responding to Verzenio after some months: anyone switch to Kisquali? Help please
Hi all My tumor markers dropped for the first few months on Verzenio/Fulvestrant, and now are climbing again. Scans didn't show progress last month but I'm terrified. Did anyone have better response switching to Kisquali and if so, what was it and how were the side effects compared to Verzenio? Verzenio and I are getting…
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Verzenio
H was your experience taking Verzenio???
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Help regarding kisqali medication
I have an aunt suffering from breast cancer, which discovered recently , the doctor prescribed her a medicine called kisqali, the problem is the price of this medicine is very high, about 3000 dollars here in Morocco , and the financial situation of the family is very difficult, my question is Are there associations that…
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When you don't fit the studies and your doctors disagree
Hi all. I'm recently diagnosed (March) with regional recurrence in right axillary nodes, 17 years after double mastectomy/chemo/tamoxifen for IDC right side (with negative sentinel node biopsy). Surgery in April removed 4 positive nodes and 4 negative nodes. Cancer is again ER+, PR+, HER2 negative (but this time HER2 low).…
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Anyone been taking Verzenio?
Hi, I found out today that I will start on an AI drug along with Verzenio after I finish my radiation in about 6 weeks. I am reading about Verzenio and it is pretty daunting reading about all the possible side effects. Anyone taking it now that could share their experience? Also, how did you get it paid for since it is…
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Beginning Targeted Therapy? Start here.
Please start a new post/discussion for a targeted therapy that you'd like to discuss, if you don't see it here already, so others can join in with their experiences. Note: If you are Stage IV (metastatic), there are many threads addressing these medications for Stage IV patients in the Stage IV forum you may find helpful.…
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Abemaciclib Verzenio for All Stages
I've noticed there is a Verzenio discussion in the Stage IV only section, and another in the Stage III forum. I'm starting this thread because I think there could be a benefit from sharing between all the stages - especially when, and if, Verzenio becomes a more common standard of treatment. I started Verzenio 14 months…
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Dizziness on verzenio or fulvestrant
Hi all, anyone get dizzy or faint while on either? I got up to pee last night and got super dizzy heading back to bed. Found myself on the floor of the bathroom after fainting 😲I’ve never passed out in my life so it was pretty scary. I was only out for a second or two, the dizziness went away quickly and I didn’t hurt…
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Long-Term Benefits of Verzenio for Early-Stage Breast Cancer Confirmed
Long-Term Benefits of Verzenio for Early-Stage Breast Cancer Confirmed Oct 30, 2023 Five years of follow-up show Verzenio continues to reduce early-stage breast cancer recurrence risk long after people stop taking it. Read more…
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How long on a CDK 4/6 inhibitor (Ibrance/verzenio/Kisqali)?
I’m sure this info is buried deep in the various stage iv threads, but I’m hoping people will post their experiences and success stories here. I think the median from the initial studies was about 2 years, but obviously there is more real world experience as time passes. Thank you!
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Treatment After CDK4/6 Inhibitors
Treatment After CDK4/6 Inhibitors Dec 5, 2023 Medical oncologist Stephanie Graff explains the treatment options available after a CDK4/6 inhibitor stops working. CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer. The CDK4/6 inhibitors are: Ibrance…
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New here, found out 4 days ago MBC
Hi all, I've written long posts on other discussion threads, but I'll keep it short here. I feel like I'll get more responses at this board till I know more about my dx and what other threads I need to check. I was dx 4 days ago with lung/abdomen and probably ureter mets. PET scan revealed. I'm not ready to hear stats…
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Stage II and on Verzenio?
I am Stage IIB, and Verzenio was approved by my insurance today. I was curious how many other "early stage" folks were taking it; my MO suggested she only has three patients on Verzenio, total. Anyone?
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Experience with Verzenio???
Hello, I am new here, I was recently diagnosed with Stage 4 breast cancer. all at once, no previous diagnosis, it was missed in previous mammograms. IN some ways i am so lucky because i didn't have to go through the mastectomy (it would have limited my ability to do my job for months, i would have lost my job for sure) or…
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NEW TO STAGE IV……WHAT ABOUT THESE TREATMENT DRUGS?
BONE METS AFTER 13 YEARS NED SUDDENLY IN TREATMENT AGAIN So in January 2023 My Oncologist sent me for scans following a high CANCER ANTIGEN 27.29 blood test, which I’ve gotten every 6 months with followups with him. Since 2009 until recently my CA 27.29 blood test was always Low ranging from 22 to 26, 27. It’s been like…
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Weight gain on treatment
I am currently on letrozole, zoladex, and verzinio with stage 4 bone mets with a hip replacement, kyphoplasty and spinal injury. It is hard to be active because of pain but I try to work out 3 days a week...I have gained 20 lbs in 6 months and am only eating 1500 calories a day. Looking for advice- I am 5"2 and never been…