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Hormone receptor status changed
My biopsy showed I was ER+ (90%), PR+ (30%) and HER2+ (3). I just had a lumpectomy and now my markers show I am ER low+ (5%), PR- (0%) and HER2+ (3). How is that possible and what does it mean if I'm ER low positive, PR -? Does that mean I won't have targeted hormone therapy? Is it better or worse than the triple positive…
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Did women who had an easy menopause and periods, have an easy time with IA?
I'm supposed to start Letrozole. I just got over chemo and RT and just waiting to get back on my feet before starting this poison. Trying to talk myself into it. I can't seem to get straight answers that satisfy me. Get tired of the Standard of Care or One Size Fits All. Why isn't a hormone test done at the beginning and…
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Estrogen prohibitor meds
Has anyone tried Anestrosole and Exemestane and have horrific leg pain. I've given up. It wakes me up and it hurts all day. They say you must take one of these for 5 years. There is no way I can do this without taking a strong pain/antiinflamatory. Discouraged Liz
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Quitting Tamoxifen
Hi ladies. I'd love to know: -How was going off Tamoxifen in general? Any side effects from Stopping? -Has anyone quit after 5 years though Dr wanted you on for 10???? Tamoxifen has made me hold Immovable weight. I've been on for a little over 5 years and would love to ditch it - unless any of you have info of problems…
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Discontinuing Anastrozole
Hi All - In 2024 I had diagnosis of Stage 2A ductal carcinoma ER/HR+ HER2 -. BRCA 2 positive. 3cm tumor no metastasis to lymph nodes. I took an aggressive stance on surgeries, opting for a double mastectomy with nipple removal (January 2024) and then removed my ovaries and fallopian tubes in September 2024. I started AI…
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Risk of discontinuing tamoxifen
I have read several reports from others that noted that their medical oncologist gave them a percentage benefit from tamoxifen (or AI’s). When I asked my MO she would not provide me with this type of information. Can anyone tell me where this type of information would come from? I want to be prepared for my next…
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Osteoporosis and Tamoxifen
I am wondering if there is anyone out there who has been taking Tamoxifen and has been diagnosed with Osteoporosis. I am 48 and just had a DEXA scan, and it confirms Osteoporosis. :( My oncologist said that typically it shouldn't cause issues in pre-menopausal women, but there are some paradoxical instances where it does!…
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PCOS
Hi, I have polycystic ovarian syndrome (PCOS). I have not been officially diagnosed but I most likely have HR+ breast cancer. I also have a serious history of depression. Tamoxifen interacts with my medications. I understand that ovarian function needs to be suppressed in pre-menopausal women which is why aromatase…
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Arimidex
Side effects?? Need advice!
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Cancer Tratment for 5 years on Stradexa
Thank you for sharing this page. I find it most interesting and informative. I am 76 years old. I do have Charcot Marie Tooth Muscular Distrophy. Had Mastectomy. Very active and healthy in every other way. I am trying to maintain that. But the side effects, and the little devels are creeping in. The predicted and expected…
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Postmenopausal bleeding after stopping tamoxifen
I was diagnosed at age 47 and was on tamoxifen for just over 3 years, which I recently stopped. Was perimenopausal upon starting it and stayed that way for over a year. I'm 51 now and have not had a period for 25 months. Well, 3 days ago, I started what looks and is acting like a period. Was heavy for 2 days and is now…
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Tamoxifen withdrawal symptoms
I`m 38 years old and I have been on Tamoxifen for 5 years.Now has been a week without it and I`m not feeling too good.Does anyone know about withdrawal symptoms?
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After first shot of Lupron
Hi I am new to this forum. My oncologist recommended a course for Lupron shoot every 3 months for 5 years as I am premenopausal. Then add Tamoxifen for 5 years after my radiation, which is schedule to start next week. The Lupron shoot was done in the middle of my cycle so I had my period at the regular time. But instead of…
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Has anyone here declined aromatase inhibitors?
I am 70 and recently had a lumpectomy for stage 1 invasive ductal carcinoma, 7mm. No lymph nodes involved. My oncologist prescribed anastrozole but I refuse to take it. I've done my homework and it's a quality of life issue for me. I already have mild arthritis, osteoporosis and thinning hair. I don't need more of that and…
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Anastrazole
hello! I’m supposed to start anastrazole but I suffered a fall and broke my tailbone. I’m wondering if anastrazole will slow the healing time for the fracture? Has anyone experienced that or heard of that? Also, I just got hot flashes and night sweats and chemo induced foot neuropathy under some control and I’m honestly so…
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Breast cancer and possible lung issues?
Hello. I just finished chemo, surgery and radiation for triple pos breast cancer that was also in a lymph node. I had a complete response to the chemo and was cleared in mid October, sentinel node negative. I recently had a ct scan of my back after a hard fall down some stairs resulting in a broken tailbone. The scan also…
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Fulvestrant and ribociclib with Turkey Tail Extract - can anyone help?
Hi to all, I am writing on behalf of my mother who is currently undergoing treatment for her metastatic breast cancer. The tumour travelled to her spine and to liver. She had to undergo extensive spinal surgery a few weeks ago which she is currently recovering from. She has now began her treatment with fulvestrant and has…
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Tamoxifen side effects
Am taking Tamoxifen for the last 3yrs now started experiencing Vaginal discharge, dryness and itching etc.
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Anastrazole
Hi! I have a question about how anastrazole works. I am taking lupron for ovarian suppression and anastrazole because I'm premenopausal. When my estradiol was checked before starting anastrazole, it was 11. When it was checked yesterday, after being on anastrazole for 3 months, it was 19. I'm confused as to why it would be…
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Letrozole and Tendonitis?
Hello all! I am coming up on 6 years of AIs with Letrozole being the most recent one. I had been on Arimidex but developed trigger thumb and fatigue over time so I switched to Letrozole. I have been okay for the most part but I now have tenosynovitis in my left wrist which won't go away and a new tendon issue on the top of…
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Herceptin alone or (Herceptin + Perjeta) together
Hi I am a 54-year-old female, and I was diagnosed with HER2-positive breast cancer last April. I completed 8 cycles of TCHP (Taxotere (docetaxel), Paraplatin (carboplatin), Herceptin (trastuzumab), and Perjeta (pertuzumab)] treatment and then underwent surgery to remove the cancer along with 5 lymph nodes. I am scheduled…
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Letrozole effectiveness long term
I just posted on another thread that, after 14 years since initial diagnosis, I now have a single suspicious supraclavicular lymph node diagnosed on annual ultrasound. I have been taking Letrozole daily since 2011 up until about a month or two ago. I just became lazy taking several meds. I am wondering if this new finding…
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Hormone therapy resistant
Hi! I was diagnosed with bc at 62, had a lumpectomy and radiation and am now 63. Currently I'm having a hard time moving forward with hormone therapy. My MO is prescribing Anastrozole for five years but I am worried about the many side effects, especially weak bones I had a bone density test six months ago and I have some…
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Hypertrophic cardiomyopathy and breast cancer
I am really scared that hormone therapy will make my heart condition worse. But if I don't take it the cancer might come back.
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Zoladex injection
Hello. I had a breast cancer surgery in last April in South Korea. Since then, I had been continuing medical treatments, including radiation and take a Tamoxifen everyday. Also, I had a Zoladex Injection every 3 months. I came back to the USA and I need to continue the Zoladex injection here. So, I tried to make an…
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Face breaking out on tamoxifen?
I've been on tamoxifen for a year now and I have all kinds of side effects from it. Weight gain 20 pounds, I'm always tired and I have no desire to do anything, hair loss/hair thinning to name some, oh yeah and those lovely hot flashes too. But also my face is breaking out with acne. I talked to my Onco and he said it is…
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osteoporosis diagnosis after on anatrozole for almost 5 years!
I foolishly googled it and now im pretty scared, it says women have a life span of 20 years after being diagnosed at the age of 50 and can break a bone just by sneezing. Can anyone share there experience with me. I haven't talked with my dr yet as I just received the info through patient gateway. All weekend all I can…
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Hormonal Therapy for Breast Cancer May Lower Dementia Risk in Older Women
Hormonal Therapy for Breast Cancer May Lower Dementia Risk in Older Women Sep 9, 2024 Protection varied by race and decreased with age. Read more…
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Aromatase inhibitors
Hi I am post lumpectomy, micro metastasis in 1 removed lymph node and now faced with the far more daunting ( to me) prospect of taking letrazole oestrogen inhibitor. Does anyone have anything positive to say about them? All I hear is the negative side effects. Others experience would be very welcome. I’m 61, normal weight,…
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New Hormone-Free Hot Flash Treatments
New Hormone-Free Hot Flash Treatments August 14, 2024 Hot flashes can dramatically affect some women’s quality of life. New research shows hormone-free options can offer relief. Read more…