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De novo questions
De novo Her2 + ladies, 1. How long were you on Herceptin and perjeta before ( if) you had progression? 2. If no progression, how long have you been Ned or stable? 3. Who all has gone off treatment? I know there’s a HUGE Denovo thread, but I get lost in there. Thank you sisters. I am grateful for the support.
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Leaky eyes anyone ?
still have eyes leaky . Feel sick all the time because of this . Help
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Intramedullary metastatic disease?
Hi, I need some support. I was just diagnosed in October and I thought I had all the mets - brain/bones/liver/lungs. Then I was diagnosed with leptomeningeal disease one month ago. (Did whole brain radiation and am now on Xeloda/Tuksya for that.) And now, I just got MRI results that say this: "New 3 mm nodule of…
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Working full time to keep health insurance
I am having trouble continuing to work full time and wonder if anyone else is dealing with the same issue. How do you deal with needing to continue to work, being basically stuck in a job because you have to keep the health insurance? Have you found a way to quit working without being financially destroyed? Disability…
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Aquaintance celebrates 25 years since advanced cancer diagnosis!
Hi everyone. I just have to shout it out because it gives me such hope. She is such a gracious, generous and caring person.
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Podcast: Verzenio Improves Overall Survival in HR+ HER2- Adv BC
Verzenio Improves Overall Survival in Hormone Receptor-Positive, HER2-Negative, Advanced Stage Breast Cancer Sep 28, 2022 Dr. Matthew Goetz explains the latest results from the MONARCH 3 study on Verzenio. At the European Society for Medical Oncology Congress 2022, Dr. Matthew Goetz presented interim overall survival…
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Podcast: Trodelvy Offers Benefits for HR+ Breast Cancer
Trodelvy Offers Benefits for Hormone Receptor-Positive Breast Cancer Sep 22, 2022 Dr. Hope Rugo discusses the latest results from the TROPiCS-02 trial showing Trodelvy improves overall survival compared to chemotherapy in metastatic, hormone receptor-positive, HER2-negative breast cancer. At the European Society for…
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leptomeningeal carcinomatosis
Hello, I found out last night at 10pm that I have leptomeningeal carcinomatosis. I have been in the hospital since Friday (it's Tuesday). I may go home today or tomorrow or who knows. I have to start WBR today. And I will be switching chemos from Gemzar to Abraxane and Carboplatin. My MO said that if the WBR doesn't work,…
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New liver progression - looking for advice/suggestions
Hi all -- I am looking for some current advice / suggestions regarding options because I have some new progression. (Note: tried searching the different threads but new format continues to make that difficult, and lots of posts are pretty old.) I'm HR+ / HER2- (+1) based on initial MBC liver biopsy 3 years ago. I've been…
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Do metastatic patients never fully get rid of the cancer?
Hi all, I am a metastatic breast cancer patient, after 12 years remission from ER+, PR+, HER2+ my cancer came back as ER-, PR-, HER2+. It is a mass in my chest, in the lymph nodes of my right armpit and a tumour on my pancreas. However both my breasts are clear. I've been receiving Paclitaxel, Pertuzumab and Trastuzumab on…
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Zoladex injection- increased bruising anyone?
I’ve been on zoladex shots for a number of years. Last month, I had a rather large and painful bruise afterwards. I chalked it up to the new MA but still reported it to my MO. Today when I went back, he tried twice to get me to come back with him and I wouldn’t. I held out for the other MA who has given me countless…
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Mets to bone only
Hi, I am stage 4 and have mets to bone only. I aspirated on an almond and was hospitalized for 5 days. I went in to have my regular labs and to have my med list reconciled since the hospital had made some changes. I asked for a raised toilet seat and a walker. The palliative care nurse then says "are you thinking about…
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Questions regarding status change and mutations
I’m so new to this and my mind is still in overdrive. Everyday I come up with a new concern and worry. Recently, it is how common is it for Her2 positive to switch to her2 negative? Also, how do we know when we should get tested for things like oik3 mutations? I don’t even know what these things mean 🤦♀️ Did I mention I’m…
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ILC (Lobular) “Unusual” Mets Sites
I have compiled a list of BCO threads, journal articles, and other resources that I hope may help those with "weird ILC mets" to find information. BCO members, please add any resources you have found about weird ILC mets. ILC sometimes spreads to "the gastrointestinal tract, genitourinary tract, peritoneum,…
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Pregnant while metastatic?
Hello. This is probably not a common topic but I wasn't sure where else to vent/ask. Has anyone gotten pregnant while on MBC treatment? I recently took a home preg test not expecting anything, but it's showing an extremely faint positive so I'm panicking & going to see my ob-gyn to check it out. I've only met one lady with…
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Xeloda and drinking some cocktails during a vacation
My MBC friends on Zoom have convinced me to travel while I am feeling great! We will be enjoying a cruise during which I will be on my second week of Xeloda. I want to have a few cocktails during the vacation the week I am on Xeloda and the following week I am off Xeloda. I don't usually have side effects from Xeloda…
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Mets to lymph node in portahepatic area
Hello…In 2013 I was diagnosed with breast cancer ILC stage 2B with 3 lymph nodes involved. I did ATC 8 rounds and 5 years of AI. No radiation Yesterday I received the biopsy news that a lymph node in the portahepatic area (near the liver) is malignant. I had no symptoms but this was found from a CT scan back in April from…
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Everolimus before capecitabine?
It seems Verzenios (abemaciclib) and fulvestrant has stopped working for me and my consultant has offered Capecitabine as the next treatment option. I haven't had chemotherapy before so this scares me a bit especially when I read the side effects! I haven't had everolimus and exemestane so was wondering if anyone has tried…
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FML - ready to throw in the towel
I feel burned out by the bi-weekly infusions, fatigue and stress from this fucking disease. I get anxiety and cry at every needle prod. Being on medically induced menopause changed my personality. I am so depressed that I can no longer be reliable to go to my appointments on time. I am losing the desire to work out. Last…
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Mentally tired
I totally get this f’ing diagnosis comes with all sorts of side effects. I can deal with the physical ones (what’s another pill or two? 🙄), but how do you deal with the mental aspect of it? The stress of stage iv is no joke. Looking to see if anyone finds relief from something I haven’t tried yet. The last couple of weeks…
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Oligiometastatic Definition
I am having difficulty finding the actual definition of Oligiometastatic. Can lymph nodes be involved? I was stage 4 Her2 positive with 2 spots in my liver and some chest node involvement. My understanding is it meets the criteria if it is 1-5 organs so, any further clarification would be much appreciated. Thank you to my…
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Bilateral Cataracts & P. Vitreal Separation
hi: Do you think mysituation Med related or metastatic cancer progression? I have stage 4 Mets x5 years on I/F therapy & Bilateral "RAPIDLY ADVANCING" Cataracts & posterior Vitreal separation (<1 mo. Apart) Rapidly advanced cataracts from grade 2-9 in ~ 6 mos. while taking Ibrance/Femara (I/F) combo for past 5 years with…
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Need Encouragement
This is my first time posting on here but wanted some encouragement. ❤️ I was diagnosed in Jan. 2022 with stage 4 her2 positive to liver. I recently have completed my chemo THP and my scans are all clear other than 2 small spots still decreasing in my liver.( which my dr. believes is scar tissue) My breast mass was quite…
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Weekly Taxol for Stage 4
I was wondering if there were any other Stage 4s doing weekly taxol. I know there is a group in the chemo forum, but most of them are doing for the 12 week cycle as part of primary treatment. According to my onc, I'll be doing weekly taxol until something changes, if you know what I mean . . . . Jennifer Edited 5/11/14: I…
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Am I the only one with super high tumor markers?
Hello. At the start of treatment in 2021, my tumor markers were in the 300 range. After each treatment failed. ( Ibrance then Piqray) my markers rose even higher. I just started Verzenio due to progression on Piqray. My Ca15-3 is 4900 and my Ca 27-19 is at 3576. I’d be more specific about treatments, but I am just too…
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Hysterectomy revealed additional mets in ovaries
Long time lurker here - can't tell you guys how much I appreciate following along on this journey. Bone mets were found in 2021, so I was on Verzino until I could no longer tolerate it, and then Ibrance since January 2022. I went in last week for a hysterectomy in order to stop taking the awful shots in my stomach to…
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15 years since diagnosis (de novo, oligometastatic)!
Sharing some news here. I responded to treatment with a complete remission and have been NED since 2008 although there is a spot they are monitoring on my left lung as first seen on my last scan (October 2021). I am still off the cancer meds and the spot hasn't grown so I'll continue to call myself NED. Of course, stable…
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12 years mbc
on July 19, I celebrated making it to 12 years. I was diagnosed with 2 liver mets, er-, her2+. I have been Ned for over 11 years and off all meds for over 7 years. When I was first diagnosed in 2010, I remembered reading that 2-3 % of stage 4 patients are “ cured” - ie- they get to Ned and remain there the rest of their…
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AIs being used by bodybuilders...
I was scanning the net reading about side effects on Aromisin and came across a whole lot of info on AIs being used by bodybuilders especially just prior to comepetition. It robs their body of estrogen so they can build mass. I found it ironic that for the last two years I have been working out so hard 4 times a week and…
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Lupron shot vs. oophorectomy
Hi all, I've been getting a Lupron shot every four weeks to suppress ovarian function so that I can be on Ibrance and Letrozole. Isn't medically induced menopause so much fun?? My MO said that it was my choice whether I wanted to continue to get this shot every four weeks forever, or to have my ovaries removed. I'm not…