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Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease
Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease Jan 6, 2026 When treating breast cancer that’s spread to the cerebrospinal fluid, proton therapy controlled the cancer better than traditional X-ray radiation. Read more…
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Enhertu Dose Reduction Results
Hi! I've had 8 infusions of Enhertu at the full dose level and have experienced side effects of fatigue and general crappiness, not in keeping with my quality of life wishes. Because of this, I'm seriously considering going to a lower dose of 4.4 mg. I can't find any data on how effective the drug is at this lower level,…
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Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors
Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors Dec 22, 2025 Results from the lidERA trial suggest that giredestrant could be a new standard of care for early-stage hormone receptor-positive breast cancer. Read more…
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Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer
Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer Dec 22, 2025 Delaying cancer growth may keep people out of the chemo chair. Read more…
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Breaking Research News from Breastcancer.org
Breastcancer.org strives to bring you updates on the latest breast cancer research through its Research News program. Medical experts at Breastcancer.org provide easy-to-understand summaries of what the research means for YOU. Favorite this thread to get notifications on all the breaking news about current breast cancer…
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Podcast: Exercise As Cancer Treatment
Exercise As Cancer Treatment January 6, 2026 Dr. Kerry Courneya discusses the CHALLENGE trial, the first study to show exercise improved survival after cancer treatment. The CHALLENGE trial found that a three-year, structured exercise program after chemotherapy for stage III colon cancer reduced the risk of the cancer…
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ELAINE 3 trial
just wanted to share with all those who have ESR1 mutation a comment from one participant. Looks like it’s working so there is hope for an approval. This is from a different site and a patient named Irit. Hi everyone, I promised an update on the clinical trial I participate in since March 2024, so here it is. The trial is…
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Liver mets: resection, ablation, SBRT, Y-90, anything else?
I'm interested in who has had local treatment for liver mets and what was your experience and outcome. I've been talking about this with my onc, and he seems a little hesitant. I have my regular appt. for a 2-mth MRI of brain and followup with rad onc. I plan to ask him about the possibilities. I think that some of the…
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Toxicity
I was diagnosed 13 years ago I am now 75 Metastatic breast cancer Her 2 positive a lifer for treatment of Herceptin/Perjeta @ 3 weeks for life. 01/26 no treatment for 8 months I have toxicity of my heart LVEF went down to 41 going in for a cardio cat scan. I am frightened that my cancer will come out of remission not being…
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DMX and Medicare Coverage
I have left side IDC and am getting ready to schedule surgery. My right side has scanned clear. I’m considering a DMX and going flat, for symmetry and so I don’t have to worry about future screenings and risks on the right side. A nurse navigator just told me that Medicare won’t pay for the double! In the two months I have…
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Does anyone else feel wiped out for hours after radiation?
Hi everyone, I’m currently halfway through radiation treatment, and I’ve been noticing that I crash completely about 2–3 hours after each session. It feels like my energy just disappears, and I need to lie down for the rest of the day. I expected some fatigue, but I didn’t realize it would hit this hard, this early. Has…
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Just diagnosed with IDC ER+ PR+ HER2+
I just was diagnosed with Invasive Ductal Carcinoma ER+ PR+ HER2+ on Dec 23rd, 2023 but still do not have an oncologist. I do not know what is normal for being diagnosed with cancer as I have never had cancer in my life before. I do not know the Stage or Grade of the tumour yet. I am in Canada. When looking up anything…
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Here I go again
I was originally diagnosed back in 9/2023 on my left side, 13 MM stage 1, grade 1 DCIS/IDC. Had lumpectomy with 20 sessions of radiation. Tried Lupron, which gave me hell for almost a year. Cant deal with Tamoxifen. Finally did a lot of holistic stuff and trying to live life again. Thought I was doing good and getting some…
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Breaking Research News from sources other than Breastcancer.org
I watch for research news on breast cancer, treatments, etc., and frequently see interesting articles. There is a topic on BCO called "Breaking Research News from Breastcancer.org." One of the moderators suggested that another topic might be appropriate for posting links and synopses of reports on research found elsewhere.…
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What mixed feelings are you carrying right now?
As a new year begins, many of us are holding more than one feeling at a time. That’s normal — and it’s okay. You might feel hopeful and scared. Grateful for support and tired of needing it. Relieved to move forward and sad that things have changed. Optimistic about each new treatment and quietly terrified it won't work.…
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Kadcyla- what to expect
I was diagnosed Dec 2025 with HER2 triple positive. Stage 1b, grade 3, tumor 2.3mm, invasive ductal carcinoma. Finished 6 rounds chemo- HPTC every 21 days, tumor shrunk by 90%. Chemo was absolute hell for me. Had my first Herceptin 3 weeks after last chemo- tolerated will. I had lumpectomy 11 days ago- dr only removed the…
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Weight Loss Drugs and Mammogram Results??
Hey all, Hope this is the same group I originally joined in 2002 when I first was diagnosed with Stage 1 breast cancer. Had lumpectomy, chemo & rads and was an active member for quite a while, but got burned out after a few years. Now, I'm seeking advice. Is anyone on the new weight loss drugs? I've been taking Zepbound…
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Back after years - lymphedema surgical resources?
Hi everyone. I was diagnosed with lymphedema I think in early 2011, so it’s been a while. I used to be on this board a lot back then. I’ve stayed active and used compression and not had much trouble with flares of swelling. My swelling never goes away completely, but it’s still soft and it’s honestly quite subtle to the…
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Thin Slices of Joy
I finished active treatment less than a month ago, and wow, you just don't bounce right back up. Before all this started I have had sciatica for a couple of years, and it worsened during treatment. In trying to recover from both, I've been feeling frustrated. Now, I'm tired of the pain, fatigue, and frustration. Oh, and…
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Hormone Replacement Therapy?
Hi all — I’ve been reading a recent research- esp. from the US, including the book Estrogen Matters, which questions the idea that women with breast cancer should automatically avoid Hormone Replacement Therapy (HRT), and how it can help with longevity etc. I’m planning to speak with my doctor about it, but I’m curious…
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Well here I am again…
After 10 years, here I am again. I meet with my oncologist and surgeon soon. Still waiting on HER Fish results. Will be going for an MRI soon. I figure I’m facing mastectomy as I had lumpectomy/radiation the first go round. It’s in same breast.
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The Next Person Game
In this game you make a statement about the next person. The next person answers true or false to that statement. They then make a statement for the next person, and so on. Example: If the person before me stated - The next person owns a dog. I would answer - True - and add my statement - The next person has curly hair.…
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Any one with Bone only Mets with ER/PR discordance?
strongly hormone positive originally 10 years( 46 years age) back IDC grade 2, stage 3A 5 years tamoxifen , 5 years Letrozole with Zolenic acid Multiple bone mets 1 year after stopping letrozole Bone biopsy came triple negative . Very concerned :(
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Recurrence after Mastectomy, then positive margins
Hello, I am hoping to connect with people who might have a similar situation to mine, although I think (?) my situation might be on the rare side. Six years ago I was diagnosed with Stage 1B IDC. I am BRCA2. I did a double mastectomy with reconstruction (implants) and was told chemo/radiation not needed since my tumor was…
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New and Confused
45yo Newly diagnosed with ILC Stage 1A and LCIS. Us found 1 tumor at 6mm. MRI biopsy found a 2nd tumor at 7mm with Lcis. Will be getting double mastectomy with reconstruction. All the waiting in between has caused so much anxiety and stress. Genetic were negative and no family x of bc. ++, her- Do you feel a sense of…
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I am not grateful to my oncologist and care team
I am facing my last treatment for triple positive breast cancer next Thursday. I had heard that ending treatment can be difficult and I have been trying to prepare myself by building other support outside my care team. However, I find that the biggest problem is the reckoning with what has happened to me. There have been 5…
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New Year 2026: A Gentler Kind of Intention. What's yours?
You don't need to set big, lofty resolutions in the New Year that can set you up to fail, causing disappointment. Some of the most powerful and attainable intentions we hear from this community sound more like this: “I’m learning to protect my energy.” “I’m saying what I need out loud, even when it’s uncomfortable.” “I’m…
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Double Mastectomy without reconstruction
Hi, I was diagnosed in July 2025 with TNBC. Stage 2a. I have gone through my 12 cycles of taxol/ carbo/ keytruda. My AC/ keytruda was stopped it landed me in hospital during Thanksgiving. I am scheduled to have a double mastectomy without reconstruction on 12/30/2025, I am a little nervous and trying not to be depressed.…
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HRT with ADH
I was diagnosed with ADH 11 years ago. Recently I have been going through perimenopause and have been having hot flashes along with other symptoms. Has anyone been put on HRT and had issues with it causing any issues with your breast health?
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tamoxifen side effects--25 years post menopausal
hi there! diagnosed in august with idc, lumpectomy and mammaoplasty (bilateral breast reduction), finished 5 fraction whole breast radiaiton on Dec 5, just started tamoxifen yesterday, 20 mg . didn't really expect side effects this soon, but… felt just generally weird both yesterday and today; sneezed a lot this morning…