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Does Cancerization of Lobules = Microinvasion?
I can’t figure this out. Googling hasn’t helped. Does anyone know if Cancerization of Lobules (COL) by high grade DCIS means that patient had a type of Microinvasion, or not? I don’t know if it’s significant: My biopsy pathology was done by the lab of first breast surgeon, whom I fired for good reason. (No point getting…
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Long term benefits vs awful short term sacrifices
Hello all Lumpectomy Oct 21, post op meeting with surgeon, she said"pathology looks good, got the tumor, nothing in the lymph nodes, treatment remains radiation A week later, met with the MO who blindsided me with my high oncotype score(31), and recommended chemo. The idea of going through LBC/risk of infection, hair loss,…
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Feeling isolated after comedocarcinoma
Anyone out there who had grade 3 DCIS, subtype comedo (aka comedocarcinoma) with expansile comedo necrosis? I was ER- and also had cancerization of lobules by high grade DCIS. I had a bilateral mastectomy 2 months ago, which my surgeon and Nurse Navigator fully supported. I think they were relieved that I understood how…
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Zoom Meet-Up Bonded by Breast Cancer: Place to Keep Chatting
Hey Everyone, Here is a place to keep sharing between meetups. Warmly, The Mods
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Older Woman Age 78 Triple Positive Update
Sharing My Current Findings: Jan 2026 Age: 78, soon to be 79 next month, Breast Cancer Confirmed: Location: Lower outer quadrant of the LEFT breast Size: 3.5 × 2.9 × 3.2 cm Nature: FDG-avid, heterogeneously enhancing, lobulated soft-tissue mass SUVmax: 8.83 Local spread: Overlying skin: Not involved Underlying chest…
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Second primary breast cancer. Other breast...
Hi! I am quite a ways down the line from my Oct, 16, 2025 dx. of Second breast cancer in the other breast. But definitely wanted to make sure to get a discussion going ..As I saw few posts on Second primary breast cancer when I was diagnosed. Background: 1st Diagnosed at 49 years of age April 2014- Left Breast. stage 1…
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💛Starting chemo in January 2026? You don’t have to do this alone.💛
This is your space to show up exactly as you are—and to be surrounded by people who get it. Whether you’re feeling scared, strong, overwhelmed, hopeful, or all of the above, we invite you to share: How you’re feeling as chemo approaches Your planned regimen (if you want to share) How you’re preparing—physically,…
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Tamoxifen side effects
Hi, I am a 69-year-old woman and and I was diagnosed with stage Ia invasive ductal carcinoma in April of this year. I had a wide surgical excision , 19 treatments of whole breast radiation, and now I have been taking Tamoxifen , 10 mg every other day for two months. I am in a Low Tam research study, that us why the dose us…
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Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer
Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer Dec 22, 2025 Delaying cancer growth may keep people out of the chemo chair. Read more…
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Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors
Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors Dec 22, 2025 Results from the lidERA trial suggest that giredestrant could be a new standard of care for early-stage hormone receptor-positive breast cancer. Read more…
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Aromatase Hormone inhibitor “5 year pill” side effects?
Has anyone used these? what were your experiences as far as side effects? cardio-muscular-bone damage?
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Podcast: Exercise As Cancer Treatment
Exercise As Cancer Treatment January 6, 2026 Dr. Kerry Courneya discusses the CHALLENGE trial, the first study to show exercise improved survival after cancer treatment. The CHALLENGE trial found that a three-year, structured exercise program after chemotherapy for stage III colon cancer reduced the risk of the cancer…
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Anyone with ATM gene variant that decided to have a mastectomy?
Hello everyone. I finished chemo today and now trying to decide between a lumpectomy with radiation or a bilateral mastectomy. I'm seriously thinking about a mastectomy. Would anyone in a similar situation as me be willing to share their feedback on what helped you decide to go for a bilateral mastectomy? How are you…
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Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease
Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease Jan 6, 2026 When treating breast cancer that’s spread to the cerebrospinal fluid, proton therapy controlled the cancer better than traditional X-ray radiation. Read more…
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Enhertu Dose Reduction Results
Hi! I've had 8 infusions of Enhertu at the full dose level and have experienced side effects of fatigue and general crappiness, not in keeping with my quality of life wishes. Because of this, I'm seriously considering going to a lower dose of 4.4 mg. I can't find any data on how effective the drug is at this lower level,…
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Breaking Research News from Breastcancer.org
Breastcancer.org strives to bring you updates on the latest breast cancer research through its Research News program. Medical experts at Breastcancer.org provide easy-to-understand summaries of what the research means for YOU. Favorite this thread to get notifications on all the breaking news about current breast cancer…
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ELAINE 3 trial
just wanted to share with all those who have ESR1 mutation a comment from one participant. Looks like it’s working so there is hope for an approval. This is from a different site and a patient named Irit. Hi everyone, I promised an update on the clinical trial I participate in since March 2024, so here it is. The trial is…
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Liver mets: resection, ablation, SBRT, Y-90, anything else?
I'm interested in who has had local treatment for liver mets and what was your experience and outcome. I've been talking about this with my onc, and he seems a little hesitant. I have my regular appt. for a 2-mth MRI of brain and followup with rad onc. I plan to ask him about the possibilities. I think that some of the…
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Toxicity
I was diagnosed 13 years ago I am now 75 Metastatic breast cancer Her 2 positive a lifer for treatment of Herceptin/Perjeta @ 3 weeks for life. 01/26 no treatment for 8 months I have toxicity of my heart LVEF went down to 41 going in for a cardio cat scan. I am frightened that my cancer will come out of remission not being…
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DMX and Medicare Coverage
I have left side IDC and am getting ready to schedule surgery. My right side has scanned clear. I’m considering a DMX and going flat, for symmetry and so I don’t have to worry about future screenings and risks on the right side. A nurse navigator just told me that Medicare won’t pay for the double! In the two months I have…
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Does anyone else feel wiped out for hours after radiation?
Hi everyone, I’m currently halfway through radiation treatment, and I’ve been noticing that I crash completely about 2–3 hours after each session. It feels like my energy just disappears, and I need to lie down for the rest of the day. I expected some fatigue, but I didn’t realize it would hit this hard, this early. Has…
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Just diagnosed with IDC ER+ PR+ HER2+
I just was diagnosed with Invasive Ductal Carcinoma ER+ PR+ HER2+ on Dec 23rd, 2023 but still do not have an oncologist. I do not know what is normal for being diagnosed with cancer as I have never had cancer in my life before. I do not know the Stage or Grade of the tumour yet. I am in Canada. When looking up anything…
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Here I go again
I was originally diagnosed back in 9/2023 on my left side, 13 MM stage 1, grade 1 DCIS/IDC. Had lumpectomy with 20 sessions of radiation. Tried Lupron, which gave me hell for almost a year. Cant deal with Tamoxifen. Finally did a lot of holistic stuff and trying to live life again. Thought I was doing good and getting some…
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Breaking Research News from sources other than Breastcancer.org
I watch for research news on breast cancer, treatments, etc., and frequently see interesting articles. There is a topic on BCO called "Breaking Research News from Breastcancer.org." One of the moderators suggested that another topic might be appropriate for posting links and synopses of reports on research found elsewhere.…
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What mixed feelings are you carrying right now?
As a new year begins, many of us are holding more than one feeling at a time. That’s normal — and it’s okay. You might feel hopeful and scared. Grateful for support and tired of needing it. Relieved to move forward and sad that things have changed. Optimistic about each new treatment and quietly terrified it won't work.…
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Kadcyla- what to expect
I was diagnosed Dec 2025 with HER2 triple positive. Stage 1b, grade 3, tumor 2.3mm, invasive ductal carcinoma. Finished 6 rounds chemo- HPTC every 21 days, tumor shrunk by 90%. Chemo was absolute hell for me. Had my first Herceptin 3 weeks after last chemo- tolerated will. I had lumpectomy 11 days ago- dr only removed the…
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4 Letter Word Game
Hi Ladies, It is time to add a four letter word game. I received an email of a forwarded scrabble game. The game started with a four letter word and kept changing by one letter. I like playing here much better. Get your 4 letter words ready. First word: Word
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Weight Loss Drugs and Mammogram Results??
Hey all, Hope this is the same group I originally joined in 2002 when I first was diagnosed with Stage 1 breast cancer. Had lumpectomy, chemo & rads and was an active member for quite a while, but got burned out after a few years. Now, I'm seeking advice. Is anyone on the new weight loss drugs? I've been taking Zepbound…
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New Year 2026: A Gentler Kind of Intention. What's yours?
You don't need to set big, lofty resolutions in the New Year that can set you up to fail, causing disappointment. Some of the most powerful and attainable intentions we hear from this community sound more like this: “I’m learning to protect my energy.” “I’m saying what I need out loud, even when it’s uncomfortable.” “I’m…
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Back after years - lymphedema surgical resources?
Hi everyone. I was diagnosed with lymphedema I think in early 2011, so it’s been a while. I used to be on this board a lot back then. I’ve stayed active and used compression and not had much trouble with flares of swelling. My swelling never goes away completely, but it’s still soft and it’s honestly quite subtle to the…