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(Seek Help) Long Term Luminal A BC transformed into TNBC (Surgery done and under chemo)
Hi everyone who sees this post. I am posting this for my mom's circumstance. She has been diagnosed with breast cancer since 2007, which was luminal A category. She had reoccurance in 2016 and has been living as a metastasis patient since then with hormone therapy. Recently she has been newly diagnosed with a TNBC cancer…
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Staying flat after nipple-sparing double mastectomy?
I'm curious if anyone has made this decision, and if they had subsequent surgeries to tighten up loose skin or fill in any concavity? I had my nipple-sparing DMX in Sept 2025, with the initial plan of reconstruction. However now that I am wrapping up chemotherapy, I am considering remaining flat. I'm not sure what to do…
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Does Cancerization of Lobules = Microinvasion?
I can’t figure this out. Googling hasn’t helped. Does anyone know if Cancerization of Lobules (COL) by high grade DCIS means that patient had a type of Microinvasion, or not? I don’t know if it’s significant: My biopsy pathology was done by the lab of first breast surgeon, whom I fired for good reason. (No point getting…
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Long term benefits vs awful short term sacrifices
Hello all Lumpectomy Oct 21, post op meeting with surgeon, she said"pathology looks good, got the tumor, nothing in the lymph nodes, treatment remains radiation A week later, met with the MO who blindsided me with my high oncotype score(31), and recommended chemo. The idea of going through LBC/risk of infection, hair loss,…
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Feeling isolated after comedocarcinoma
Anyone out there who had grade 3 DCIS, subtype comedo (aka comedocarcinoma) with expansile comedo necrosis? I was ER- and also had cancerization of lobules by high grade DCIS. I had a bilateral mastectomy 2 months ago, which my surgeon and Nurse Navigator fully supported. I think they were relieved that I understood how…
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Older Woman Age 78 Triple Positive Update
Sharing My Current Findings: Jan 2026 Age: 78, soon to be 79 next month, Breast Cancer Confirmed: Location: Lower outer quadrant of the LEFT breast Size: 3.5 × 2.9 × 3.2 cm Nature: FDG-avid, heterogeneously enhancing, lobulated soft-tissue mass SUVmax: 8.83 Local spread: Overlying skin: Not involved Underlying chest…
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💛Starting chemo in January 2026? You don’t have to do this alone.💛
This is your space to show up exactly as you are—and to be surrounded by people who get it. Whether you’re feeling scared, strong, overwhelmed, hopeful, or all of the above, we invite you to share: How you’re feeling as chemo approaches Your planned regimen (if you want to share) How you’re preparing—physically,…
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Tamoxifen side effects
Hi, I am a 69-year-old woman and and I was diagnosed with stage Ia invasive ductal carcinoma in April of this year. I had a wide surgical excision , 19 treatments of whole breast radiation, and now I have been taking Tamoxifen , 10 mg every other day for two months. I am in a Low Tam research study, that us why the dose us…
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Aromatase Hormone inhibitor “5 year pill” side effects?
Has anyone used these? what were your experiences as far as side effects? cardio-muscular-bone damage?
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Anyone with ATM gene variant that decided to have a mastectomy?
Hello everyone. I finished chemo today and now trying to decide between a lumpectomy with radiation or a bilateral mastectomy. I'm seriously thinking about a mastectomy. Would anyone in a similar situation as me be willing to share their feedback on what helped you decide to go for a bilateral mastectomy? How are you…
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Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease
Proton Therapy Better Than Traditional Radiation for Leptomeningeal Disease Jan 6, 2026 When treating breast cancer that’s spread to the cerebrospinal fluid, proton therapy controlled the cancer better than traditional X-ray radiation. Read more…
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Enhertu Dose Reduction Results
Hi! I've had 8 infusions of Enhertu at the full dose level and have experienced side effects of fatigue and general crappiness, not in keeping with my quality of life wishes. Because of this, I'm seriously considering going to a lower dose of 4.4 mg. I can't find any data on how effective the drug is at this lower level,…
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Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors
Giredestrant Reduces Recurrence Risk More Than Tamoxifen, Aromatase Inhibitors Dec 22, 2025 Results from the lidERA trial suggest that giredestrant could be a new standard of care for early-stage hormone receptor-positive breast cancer. Read more…
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Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer
Adding Tukysa to First Treatments Delays Growth of Metastatic HER2-Positive Breast Cancer Dec 22, 2025 Delaying cancer growth may keep people out of the chemo chair. Read more…
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Breaking Research News from Breastcancer.org
Breastcancer.org strives to bring you updates on the latest breast cancer research through its Research News program. Medical experts at Breastcancer.org provide easy-to-understand summaries of what the research means for YOU. Favorite this thread to get notifications on all the breaking news about current breast cancer…
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Podcast: Exercise As Cancer Treatment
Exercise As Cancer Treatment January 6, 2026 Dr. Kerry Courneya discusses the CHALLENGE trial, the first study to show exercise improved survival after cancer treatment. The CHALLENGE trial found that a three-year, structured exercise program after chemotherapy for stage III colon cancer reduced the risk of the cancer…
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Liver mets: resection, ablation, SBRT, Y-90, anything else?
I'm interested in who has had local treatment for liver mets and what was your experience and outcome. I've been talking about this with my onc, and he seems a little hesitant. I have my regular appt. for a 2-mth MRI of brain and followup with rad onc. I plan to ask him about the possibilities. I think that some of the…
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Toxicity
I was diagnosed 13 years ago I am now 75 Metastatic breast cancer Her 2 positive a lifer for treatment of Herceptin/Perjeta @ 3 weeks for life. 01/26 no treatment for 8 months I have toxicity of my heart LVEF went down to 41 going in for a cardio cat scan. I am frightened that my cancer will come out of remission not being…
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DMX and Medicare Coverage
I have left side IDC and am getting ready to schedule surgery. My right side has scanned clear. I’m considering a DMX and going flat, for symmetry and so I don’t have to worry about future screenings and risks on the right side. A nurse navigator just told me that Medicare won’t pay for the double! In the two months I have…
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Does anyone else feel wiped out for hours after radiation?
Hi everyone, I’m currently halfway through radiation treatment, and I’ve been noticing that I crash completely about 2–3 hours after each session. It feels like my energy just disappears, and I need to lie down for the rest of the day. I expected some fatigue, but I didn’t realize it would hit this hard, this early. Has…
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Here I go again
I was originally diagnosed back in 9/2023 on my left side, 13 MM stage 1, grade 1 DCIS/IDC. Had lumpectomy with 20 sessions of radiation. Tried Lupron, which gave me hell for almost a year. Cant deal with Tamoxifen. Finally did a lot of holistic stuff and trying to live life again. Thought I was doing good and getting some…
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What mixed feelings are you carrying right now?
As a new year begins, many of us are holding more than one feeling at a time. That’s normal — and it’s okay. You might feel hopeful and scared. Grateful for support and tired of needing it. Relieved to move forward and sad that things have changed. Optimistic about each new treatment and quietly terrified it won't work.…
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Kadcyla- what to expect
I was diagnosed Dec 2025 with HER2 triple positive. Stage 1b, grade 3, tumor 2.3mm, invasive ductal carcinoma. Finished 6 rounds chemo- HPTC every 21 days, tumor shrunk by 90%. Chemo was absolute hell for me. Had my first Herceptin 3 weeks after last chemo- tolerated will. I had lumpectomy 11 days ago- dr only removed the…
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Weight Loss Drugs and Mammogram Results??
Hey all, Hope this is the same group I originally joined in 2002 when I first was diagnosed with Stage 1 breast cancer. Had lumpectomy, chemo & rads and was an active member for quite a while, but got burned out after a few years. Now, I'm seeking advice. Is anyone on the new weight loss drugs? I've been taking Zepbound…
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Hormone Replacement Therapy?
Hi all — I’ve been reading a recent research- esp. from the US, including the book Estrogen Matters, which questions the idea that women with breast cancer should automatically avoid Hormone Replacement Therapy (HRT), and how it can help with longevity etc. I’m planning to speak with my doctor about it, but I’m curious…
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Well here I am again…
After 10 years, here I am again. I meet with my oncologist and surgeon soon. Still waiting on HER Fish results. Will be going for an MRI soon. I figure I’m facing mastectomy as I had lumpectomy/radiation the first go round. It’s in same breast.
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Any one with Bone only Mets with ER/PR discordance?
strongly hormone positive originally 10 years( 46 years age) back IDC grade 2, stage 3A 5 years tamoxifen , 5 years Letrozole with Zolenic acid Multiple bone mets 1 year after stopping letrozole Bone biopsy came triple negative . Very concerned :(
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Recurrence after Mastectomy, then positive margins
Hello, I am hoping to connect with people who might have a similar situation to mine, although I think (?) my situation might be on the rare side. Six years ago I was diagnosed with Stage 1B IDC. I am BRCA2. I did a double mastectomy with reconstruction (implants) and was told chemo/radiation not needed since my tumor was…
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New and Confused
45yo Newly diagnosed with ILC Stage 1A and LCIS. Us found 1 tumor at 6mm. MRI biopsy found a 2nd tumor at 7mm with Lcis. Will be getting double mastectomy with reconstruction. All the waiting in between has caused so much anxiety and stress. Genetic were negative and no family x of bc. ++, her- Do you feel a sense of…
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I am not grateful to my oncologist and care team
I am facing my last treatment for triple positive breast cancer next Thursday. I had heard that ending treatment can be difficult and I have been trying to prepare myself by building other support outside my care team. However, I find that the biggest problem is the reckoning with what has happened to me. There have been 5…
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- Research News 116
- Mastectomy 111
- Podcast 97
- Metastatic Breast Cancer (MBC or Stage IV) 95
- Invasive Ductal Carcinoma (IDC) 86
- Lumpectomy 78
- tamoxifen (Nolvadex; Apo-Tamox; Tamofen; Tamone; Soltamox) 69
- Anxiety 68
- Triple-Negative Breast Cancer 63
- Ductal Carcinoma In Situ (DCIS) 58
- Lumpectomy vs. mastectomy 57
- ER-positive 53
- Breast implants 49
- Femara (letrozole) 45
- Taxol (paclitaxel) 42
- AIs (Aromatase Inhibitors) 42
- AC: Adriamycin and Cytoxan 41
- Arimidex (anastrozole) 41
- Dense breasts 41
- AC+T (Taxol): Adriamycin and Cytoxan plus Taxol 40
- Abdominal Pain 36
- Recurrent Breast Cancer 36
- Kisqali (ribociclib) 36
- Hormone receptor-positive HER2-negative 36
- Verzenio (abemaciclib) 36